DRL-17822
/ Dr. Reddy’s
- LARVOL DELTA
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June 12, 2019
Effect of Food on the Pharmacokinetics of 2 Formulations of DRL-17822, a Novel Selective Cholesteryl Ester Transfer Protein (CETP) Inhibitor, in Healthy Males.
(PubMed, Clin Pharmacol Drug Dev)
- "Consuming breakfast increased the effect of DRL-17822 on high-density lipoprotein. Taken together, our results indicate that by improving its formulation, DRL-17822 has a favorable exposure profile and therefore a more predictable food effect profile."
Clinical • Journal • PK/PD data
April 07, 2020
The effect of food and formulation on the population pharmacokinetics of CETP inhibitor DRL-17822 in healthy male volunteers.
(PubMed, Br J Clin Pharmacol)
- "The final model adequately characterised the pharmacokinetic data of DRL-17822 in healthy males including the complex interaction of food and drug formulation. The ASD formulation has a lower food effect on bio-availability compared with the nanocrystal formulation."
Clinical • Journal • PK/PD data
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