Lanconone (E-OA-07) / ENovate Biolife - LARVOL DELTA

Effects of dietary supplements on patients with osteoarthritis: a systematic review and network meta-analysis. (PubMed, J Integr Med) - "Passion fruit peel extract was the best supplement for improving WOMAC pain and function scores in patients with osteoarthritis, followed by Lanconone and collagen. However, further large-scale, well designed RCTs are required to substantiate these promising findings. Please cite this article as: Chen CS, Wen L, Yang F, Deng YC, Ji JH, Chen RJ, Chen Z, Chen G, Gu JY. Effects of dietary supplements on patients with osteoarthritis: A systematic review and network meta-analysis. J Integr Med. 2025; Epub ahead of print."

Journal • Retrospective data • Review • Immunology • Osteoarthritis • Pain • Rheumatology

Efficacy of dietary supplements for treating knee osteoarthritis: a systematic review and network meta-analysis. (PubMed, Front Nutr) - "In comparison to the placebo, NEM (for stiffness), Aflapin (for pain), and E-OA-07 (for knee function and WOMAC total score) were discerned as the most effective interventions for the treatment of KOA. https://www.crd.york.ac.uk/prospero/."

Journal • Retrospective data • Review • Immunology • Osteoarthritis • Pain • Rheumatology

Effect of LANCONONE in Weight-bearing Joint Pain (clinicaltrials.gov) - P=N/A; N=72; Active, not recruiting; Sponsor: Vedic Lifesciences Pvt. Ltd.; Recruiting ➔ Active, not recruiting

Clinical • Enrollment closed • Immunology • Musculoskeletal Diseases • Orthopedics • Osteoarthritis • Pain • Rheumatology

Effect Of E-OA-07 On Improving Joint Health And Mobility In Individuals With Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study. (PubMed, J Pain Res) - "At the end of the study period, there was a clinically relevant change of 45.55%, 45.91% and 38.19% for pain, stiffness and physical function, respectively. Moving forward, studies could be planned for understanding the cartilage regenerative properties of E-OA-07."

Clinical • Journal

Effect of LANCONONE in Weight-bearing Joint Pain (clinicaltrials.gov) - P=N/A; N=72; Completed; Sponsor: Vedic Lifesciences Pvt. Ltd.; Active, not recruiting ➔ Completed

Clinical • Trial completion