HBP-bound-doxorubicin (12B80)
/ Atlanthera
- LARVOL DELTA
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November 28, 2020
Phase I dose escalation study of 12b80 (hydroxybisphosphonate linked doxorubicin) in naturally occurring osteosarcoma.
(PubMed, Oncotarget)
- "In dogs, 12b80 is overall well tolerated and expends the MTD of doxorubicin up to four times the standard dose of 30 mg/m. These results demonstrate the potential therapeutic benefit of 12b80 in canine and human osteosarcoma."
Journal • P1 data • Gastroenterology • Gastrointestinal Disorder • Immunology • Oncology • Osteosarcoma • Sarcoma • Solid Tumor
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