Helios ocular insert (bimatoprost sustained release insert) / AbbVie - LARVOL DELTA

Pilot Study: Heart Rate and Heart Rate Variability Indices in Mules Evaluated by 24-Hour Electrocardiogram. (PubMed, Animals (Basel)) - "Vision 5 Holter Analysis Software was utilized for ECG review and analysis...Arrhythmias were consistent with the range of cardiac rhythms observed in horses and more frequent than reported in donkeys. Further investigation with a larger sample size of mules is warranted to determine if reference values for horses should continue to be used to assess mules and to investigate the prevalence of arrhythmias and their clinical relevance in the mule."

Journal • Cardiovascular

Risk factors associated with suicidal ideation among cancer patients: a systematic review and meta-analysis. (PubMed, Front Psychol) - "Software Review Manager 5 (vision 5.4) was used for Meta-analyses...Being unmarried, living alone, less educated, living in rural, financial problems, pain, vomiting, PTSD, psychiatric illness history, lower social functioning, childhood adversity experience, anxiety, depression, demoralization, panic disorder were risk factors for suicidal ideation among cancer patients. This review provided evidence-based information for identifying and reducing the risk of suicide in cancer survivors.Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/, CRD42023433639."

Retrospective data • Review • CNS Disorders • Depression • Mental Retardation • Mood Disorders • Oncology • Pain • Post-traumatic Stress Disorder • Psychiatry • Suicidal Ideation

Macular Hole in a patient with Pentosan Polysulfate Maculopathy. (PubMed, Retin Cases Brief Rep) - "PPS-related maculopathy can lead to severe retinal atrophy and a subsequent degenerative macular hole. A high index of suspicion is required for early detection and cessation of drug to prevent this irreversible vision loss."

Journal • Age-related Macular Degeneration • Interstitial Cystitis • Macular Degeneration • Retinal Disorders

Low Vision Coding and Billing 2023 - Lessons Learned (AOA 2023) - "To learn the principles and rules of ICD-10 and CPT-4 as they relates to Iow vision 5. To understand the importance of proper record documentation to support the CPT codes a clinician submits to an insurance company CEU Code: AOA276-LV; CW-0007-23"

Ophthalmology

COVID-19 mRNA Vaccine-Associated Uveitis Leading to Diagnosis of Sarcoidosis: Case Report and Review of Literature. (PubMed, J Investig Med High Impact Case Rep) - "A 34-year-old Japanese person with male gender identity who had been taking intramuscular injection of methyltestosterone depot for 11 years after bilateral mastectomy noticed blurred vision 5 days after the second vaccination for COVID-19 (Tozinameran; Pfizer-BioNTech) in the interval of 3 weeks following the first vaccination...The systemic symptoms were relieved by oral prednisolone 20 mg daily. Even though the causal relationship remains undetermined, this case is unique at the point that vaccine-associated uveitis led to the detection of pulmonary lesions and lymphadenopathy, resulting in clinical and pathological diagnosis of sarcoidosis. In literature review, 3 patients showed sarcoidosis-like diseases after COVID-19 vaccination: 2 patients were diagnosed clinically as Lofgren syndrome with acute onset of erythema nodosum and ankle swelling, with or without mediastinal and hilar lymphadenopathy, whereas 1 patient with mediastinal lymphadenopathy but no uveitis was..."

Journal • Review • Dermatology • Immunology • Infectious Disease • Novel Coronavirus Disease • Ocular Inflammation • Ophthalmology • Sarcoidosis • Uveitis • IL2

[VIRTUAL] Healthcare transition outcomes among young adults with pediatric-onset chronic pain (IASP 2021) - "Drotar-Crawford Postdoctoral Fellowship Research Grant, American Psychological Association, Division 54 (Society of Pediatric Psychology) Background and Aims: One in four adolescents experience chronic pain, and, of these, an estimated half will experience pain persisting into adulthood... For adolescents with chronic pain, our findings indicate a poor prognosis of chronic pain persisting into young adulthood accompanied by significant elevations in disability and mental health concerns. Although participants demonstrate the need for continued chronic pain health services, many may experience gaps in care, highlighting the critical need to develop transition guidelines and services in this population."

Clinical • CNS Disorders • Depression • Mood Disorders • Pain • Pediatrics • Psychiatry • Suicidal Ideation

miR-590-5p targets RMND5A and promotes migration in pancreatic adenocarcinoma cell lines. (PubMed, Oncol Lett) - "Required for meiotic nuclear division 5 homolog A (RMND5A) functions as an E3 ubiquitin ligase...In addition, overexpression of miR-590-5p attenuated the promoting effects of RMND5A on the migration of AsPC-1 and PANC-1 cells. The results of the present study may further elucidate the mechanisms underlying PAAD progression and provide novel targets for the treatment of PAAD."

Journal • Preclinical • Gastrointestinal Cancer • Hepatology • Oncology • Pancreatic Adenocarcinoma • Pancreatic Cancer • Solid Tumor • Targeted Protein Degradation • RMND5A

"Colleagues and Friends, we have opened our search for the 2022 ECP Editorial Fellow. Please RT. @APADiv28 @apadivision50 @division_55 @APA_Journals" (@WilliamStoops)

First case of periprosthetic joint infection due to Clostridioides difficile in China. (PubMed, BMC Infect Dis) - "A rapid and accurate sample collection is significant for culture results, making an outstanding contribution to the successful treatment."

Clinical • Journal • Infectious Disease • Orthopedics • Pain

[VIRTUAL] Effect of Age on Reduced Child-Reported Eye-Related Quality of Life and Functional Vision in Strabismus (ARVO 2021) - " A significantly greater proportion of 12- to 17-year-olds vs 5- to 11-year-olds had reduced scores on each of the four Child PedEyeQ domains: Social 89% vs 19%, (mean difference 71%, 95% CI 56% to 85%; P<0.001), Frustration/Worry 75% vs 21% (mean difference 54%, 95% CI 35% to 72%; P<0.001), Functional Vision 57% vs 34% (mean difference 23%, 95% CI 1% to 44%; P=0.044) and Bothered by Eyes/Vision 57% vs 31% (mean difference 26%, 95% CI 4% to 47%; P=0.02)... A greater proportion of adolescents report reduced (below the 5th percentile threshold) functional vision and reduced ER-QOL domain scores compared with 5- to 11-year-olds, especially on the Social and Frustration/Worry domains. This effect of child age likely reflects, at least in part, a more realistic self-concept in adolescents. Interpretation of individual scores in younger clinical populations is also made challenging by the considerable variability in 5- to 11-year-old normal controls, such that thresholds..."

Clinical • HEOR • Ophthalmology • Strabismus

"We want to hear from you—looking for make a resource for trainees and ECRs! @APA_Journals @APADiv28 @apadivision50 @division_55" (@WilliamStoops)

"@APADiv28 @apadivision50 @division_55" (@WilliamStoops)

"Terrific idea, @SamuelAcuff, @keanan_joyner and @apadivision50! I was delighted to sign up!" (@WilliamStoops)

Patterns of ellipsoid zone change associated with visual outcome for diabetic macular oedema. (PubMed, Clin Exp Optom) - "Higher EZ scores (p = 0.016), but not baseline EZ disruption (p = 0.56), were less likely to have improvement of final vision 5 letters or more. Macular perfusion status played an independent role in EZ dynamics. Duration of EZ disruption could be more predictive than baseline status for improvement of vision over 12 months."

Journal • Developmental Disorders • Diabetic Macular Edema • Macular Edema • Ophthalmology • Retinal Disorders

"Sorry for the delay, but here's the ToC for our first issue of 2021! @APA_Journals @APADiv28 @apadivision50 @division_55 https://t.co/DHzHmyndst" (@WilliamStoops)

"Great question. @AAAP1985 @apadivision50 would be interested in their takes as well. @ASAMorg too." (@ADAWnews)

Ozone Induced Encephalopathy: a novel iatrogenic entity. (PubMed, Eur J Neurol) - "OIE should be considered in patients presenting with neurological symptoms in close relation to OT. OIE is likely a novel iatrogenic entity with a complex pathogenesis; it is probably under-reported because mimicking other neurological conditions."

Journal • Review • CNS Disorders • Migraine • Musculoskeletal Pain • Ophthalmology • Otorhinolaryngology • Pain • Vertigo • MRI

"Unless you could argue an exception to the division 5 labelling. But then again, I would definitely placebo control any such study so maybe it's not so bad." (@DrToddLee)

Clinical

"And yet, prescribing psychologists, who would be ideal Psychedelic Practitioners, are routinely and rigorously rejected by psychiatry. Deep knowledge of therapy and pharmacology is a valuable combo that must be supported. @division_55 @APADiv28" (@drrickbarnett)

Psychiatry

Multi-kingdom characterization of the core equine fecal microbiota based on multiple equine (sub)species. (PubMed, Anim Microbiome) - "Whilst differences were observed between equine types, a core fecal microbiota existed across all the equines. This core was composed primarily of a few predominant bacterial taxa, the majority of which are novel and lack cultured representation. The lack of microbial cultures representing the predominant taxa needs to be addressed, as their availability is essential to gain fundamental knowledge of the microbial functions that underpin the equine hindgut ecosystem."

Journal

Using the RETeval Device in Healthy Children to Establish Normative Electroretinogram Values. (PubMed, J Pediatr Ophthalmol Strabismus) - "The handheld RETeval system is a useful tool for obtaining full-field ERGs in children without anesthesia. Moderate positive correlations were observed between age and oscillatory potential and scotopic dim flash amplitude. A strong correlation was found between age and cone a-wave implicit time. The current study provides a baseline of normative full-field ERG values in children. [J Pediatr Ophthalmol Strabismus. 2021;58(1):17-22.]."

Clinical • Journal • Anesthesia • Ophthalmology • Pediatrics • Retinal Disorders • Strabismus

Peter F. Merenda (1922-2019). (PubMed, Am Psychol) - "Peter's contributions were honored by awards from his community; state (RIPA); region (NEPA); APA Karl Heiser Presidential Award for Distinguished Scientific Contributions (Division 5); James McKeon Cattell Fellow Award; and awards from Portugal, the Republic of China, and Italy. Peter Francis Merenda was a remarkable individual who lived an extraordinary life, impacting people far and wide. In his 97-plus years, Peter accomplished much and gave back much to others- his family, friends, colleagues, students, community, country, and internationally."

Journal

Knowledge and attitudes regarding Covid-19 among Syrian refugee women in Jordan. (PubMed, Int J Clin Pract) - "There are gaps in the knowledge and attitude of Syrian refugee mothers in the Governorate of Irbid in relation to the Covid-19 pandemic. There is a need for further health education measures."

Clinical • Journal • Infectious Disease • Novel Coronavirus Disease

"advocacy for psychology and psychologists—one of the most important things @apa does in my opinion! @APADiv28 @apadivision50 @APAScience @apadiv25 @division_55" (@WilliamStoops)

[VIRTUAL] Preclinical prenatal alcohol exposure and placental insufficiency result in altered cerebellar peduncle microstructure (WSMRF 2021) - "Regions of Interest were analyzed with Bruker’s Paravision 5.1 and diffusion eigenvectors measured...Specifically, the superior cerebellar peduncle, which consists primarily of efferent pathways, is more vulnerable to injury following these prenatal insults compared to other areas of the cerebellum. Additional studies are needed to further characterize this injury and the impact this may have on function related to these critical brain regions."

Preclinical • MRI