TAS-108 / Otsuka, Nobelpharma, SRI International - LARVOL DELTA

SR-16234, a Unique Selective Estrogen Receptor Modulator, Suppressed Proliferation and Pain-Related Factor Expression by Inhibition of the Nuclear Factor-kappa B Pathway in Endometriotic Stromal Cells. (PubMed, Am J Reprod Immunol) - "SR appears to be a potential therapeutic agent for endometriosis by suppressing inflammatory and pain-related factor expressions by inhibiting the nuclear factor-kappa B pathway."

Journal • Stroma • Endometriosis • Gynecology • Inflammation • Oncology • Pain • Women's Health • CXCL8 • ER • IL6 • NFKBIA • TNFA • TRPV1

New insights into the efficacy of SR-16234, a selective estrogen receptor modulator, on the growth of murine endometriosis-like lesions. (PubMed, Am J Reprod Immunol) - "SR has a regressive effect on the development of murine endometriosis-like lesions."

Journal • Preclinical