CRD-102
/ Avacta
- LARVOL DELTA
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May 20, 2017
Lenalidomide induction and maintenance therapy for transplant eligible myeloma patients: Results of the Myeloma XI study.
(ASCO 2017)
- P3; "...For TE patients the induction question compared Len or Thal plus cyclophosphamide and dexamethasone (CRD vs CTD) continued for a minimum of 4 cycles and to max...2042 TE patients underwent the induction randomization (CRD 1021, CTD 1021)... CRD was associated with deeper responses than CTD, and with a PFS and OS benefit. The best outcomes were associated with Len induction plus Len maintenance. Our findings support continuing Len therapy through induction until disease progression."
Clinical • Biosimilar • Multiple Myeloma
January 30, 2018
CRD-102 for Right Heart Failure in Patients With Left Ventricular Assist Devices
(clinicaltrials.gov)
- P1/2; N=10; Recruiting; Sponsor: Cardiora Pty. Ltd.; Not yet recruiting ➔ Recruiting; Initiation date: Aug 2017 ➔ Feb 2018
Enrollment open • Trial initiation date • Biosimilar • Cardiovascular • Heart Failure
July 14, 2017
CRD-102 for Right Heart Failure in Patients With Left Ventricular Assist Devices
(clinicaltrials.gov)
- P1/2; N=10; Not yet recruiting; Sponsor: Cardiora Pty. Ltd.
New P1/2 trial • Biosimilar • Cardiovascular • Heart Failure
August 03, 2018
Extended Release Oral Milrinone, CRD-102, for Advanced Heart Failure.
(PubMed, Am J Cardiol)
- "In conclusion, the present study demonstrates evidence of beneficial actions of extended release milrinone in advanced HF. Longer-term randomized clinical trial data are required."
Journal
June 25, 2019
CRD-102 for Right Heart Failure in Patients With Left Ventricular Assist Devices
(clinicaltrials.gov)
- P1/2; N=6; Completed; Sponsor: Cardiora Pty. Ltd.; Recruiting ➔ Completed; N=10 ➔ 6; Trial primary completion date: Apr 2019 ➔ Oct 2018
Clinical • Enrollment change • Trial completion • Trial primary completion date
February 06, 2019
CRD-102 for Right Heart Failure in Patients With Left Ventricular Assist Devices
(clinicaltrials.gov)
- P1/2; N=10; Recruiting; Sponsor: Cardiora Pty. Ltd.; Trial completion date: Aug 2018 ➔ May 2019; Trial primary completion date: Aug 2018 ➔ Apr 2019
Clinical • Trial completion date • Trial primary completion date
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