J2H-1802 / J2HBiotech - LARVOL DELTA

Anti-Psoriatic Effects of J2H-1802, a Mycophenolate Mofetil and 5-Aminosalicylic Acid Hybrid, in an Imiquimod-Induced Psoriasis-like Mouse Model. (PubMed, Pharmaceutics) - "In addition, J2H-1802 significantly reduced serum tumor necrosis factor-α (TNF-α) levels and suppressed pro-inflammatory cytokine expression, including IL-1β, IL-6, IL-17, and TNF-α, in psoriatic skin. J2H-1802 alleviates both local and systemic inflammatory features of psoriasis, suggesting its potential as a therapeutic candidate for targeting IL-23/Th17-mediated inflammatory pathways."

Journal • Preclinical • Dermatology • Immunology • Oncology • Psoriasis • Systemic Inflammatory Response Syndrome • IL17A • IL1B • IL23A • IL6 • TNFA