darexaban maleate (YM150) / Astellas - LARVOL DELTA

The Effects of Pectin Structure on Emulsifying, Rheological, and In Vitro Digestion Properties of Emulsion. (PubMed, Foods) - "In this experiment, the structures of six kinds of commercial pectin, including LM 101 AS (101), LM 104 AS (104), 121 SLOW SET (121), YM 150 H (150), LM 13 CG (13CG), and β-PECTIN (β-P) were determined, and the effects of pectin structure on emulsion emulsification, rheology and in vitro digestibility were studied...The smaller the DM, the more negative charge the emulsion carried, and the higher the release rate of free fatty acids. The results provided a basis for the rational selection and structural design of the pectin emulsifier."

Journal • Preclinical

A study evaluating safety and tolerability of YM150 compared to warfarin in subjects with atrial fibrillation (OPAL-2) (clinicaltrials.gov) -

Astellas;P2, N=1,280

Cardiovascular