estradiol transdermal gel (BHR-200) / Besins Healthcare - LARVOL DELTA

Is Serial Follow Up including Serum Metal Ion Analysis and Hip X-Rays after Birmingham Hip Resurfacing Always Necessary? – A Retrospective Cohort Study (AAOS 2024) - " A total of 288 patients operated with a unilateral BHR 2001-2014 with at least one follow up including hip x-ray and serum metal ion analysis until 2022 were included in the study... Patients after BHR without risk factors at first follow up do not seem to need continuous follow up with hip x-rays serum metal ion analysis. On the other hand, patients with serum metal concentration >5 μg/l and decreasing SSA should be monitored."

Retrospective data • Growth Hormone Deficiency (Adult)

MASTERS: Maintaining Suppression of Testosterone With Transdermal Estradiol Gel (clinicaltrials.gov) - P2; N=120; Recruiting; Sponsor: BHR Pharma, LLC; Trial primary completion date: Jan 2016 ➔ Jan 2017

Clinical • Trial primary completion date

MASTERS: Maintaining Suppression of Testosterone With Transdermal Estradiol Gel (clinicaltrials.gov) - P2; N=120; Not yet recruiting; Sponsor: BHR Pharma, LLC

Clinical • New P2 trial

MASTERS: Maintaining Suppression of Testosterone With Transdermal Estradiol Gel (clinicaltrials.gov) - P2; N=34; Terminated; Sponsor: BHR Pharma, LLC; N=120 ➔ 34; Recruiting ➔ Terminated; Inability to recruit patients

Clinical • Enrollment change • Trial termination

MASTERS: Maintaining Suppression of Testosterone With Transdermal Estradiol Gel (clinicaltrials.gov) - P2; N=120; Not yet recruiting; Sponsor: BHR Pharma, LLC; Initiation date: Mar 2015 ➔ Jun 2015

Clinical • Trial initiation date

MASTERS: Maintaining Suppression of Testosterone With Transdermal Estradiol Gel (clinicaltrials.gov) - P2; N=34; Terminated; Sponsor: BHR Pharma, LLC; Trial completion date: Dec 2018 ➔ Jan 2018

Clinical • Trial completion date

MASTERS: Maintaining Suppression of Testosterone With Transdermal Estradiol Gel (clinicaltrials.gov) - P2; N=120; Recruiting; Sponsor: BHR Pharma, LLC; Trial primary completion date: Jan 2017 ➔ Jun 2017

Clinical • Trial primary completion date

MASTERS: Maintaining Suppression of Testosterone With Transdermal Estradiol Gel (clinicaltrials.gov) - P2; N=120; Recruiting; Sponsor: BHR Pharma, LLC; Not yet recruiting ➔ Recruiting

Clinical • Enrollment open