methylprednisolone sodium succinate
/ Generic mfg.
- LARVOL DELTA
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March 26, 2026
Unusual Co-Presentation of Two Skin Patterns in a Case of Granulomatosis with Polyangiitis: A Case Report and Literature Review.
(PubMed, Case Rep Dermatol)
- "The patient responded well to immunosuppressive therapy, including intravenous methylprednisolone, cyclophosphamide, and plasma exchange therapy. This case shows an unusual combination of bullous vasculitis and PNGD in a patient with GPA, highlighting the importance of recognizing uncommon skin lesions as possible clues to underlying systemic vasculitis."
Journal • Chronic Cough • Cough • Dermatitis • Dermatology • Glomerulonephritis • Immunology • Inflammation • Lupus Nephritis • Nephrology • Pulmonary Disease • Rare Diseases • Respiratory Diseases • Vasculitis
March 26, 2026
Longitudinal extensive anti-AMPA-GluR3-related transverse myelitis and favorable therapeutic response: A case report and review of literature.
(PubMed, World J Clin Pediatr)
- "The frequency of LETM associated with mGluR3abs is unknown; this report may contribute to expanding the understanding of it."
Journal • Back Pain • CNS Disorders • Inflammation • Musculoskeletal Pain • Pain
March 26, 2026
Anti-GluK2 antibody-associated autoimmune encephalomyelitis with delayed MRI abnormalities: case report.
(PubMed, Neuroscience)
- "The patient received intravenous methylprednisolone combined with immunoglobulin therapy...Elevated serum IgE may be involved in pathogenesis. Early diagnosis and immunotherapy appear critical for clinical improvement."
Journal • CNS Disorders • Epilepsy • Gastrointestinal Disorder • Immunology • Inflammatory Bowel Disease • Multiple Sclerosis • GRIK2
March 26, 2026
EXAFIP2: Glucocorticoids Versus Placebo for the Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis
(clinicaltrials.gov)
- P3 | N=110 | Recruiting | Sponsor: Fondation Hôpital Saint-Joseph | Not yet recruiting ➔ Recruiting
Enrollment open • Idiopathic Pulmonary Fibrosis • Immunology • Pulmonary Disease • Respiratory Diseases
March 20, 2026
FALSE POSITIVE ANTI-GBM ANTIBODIES IN A PATIENT WITH BOVINE BIOPROSTHESIS PRESENTING WITH PULMONARY HAEMORRHAGE: A CASE REPORT
(ISN-WCN 2026)
- "In view of persistent pulmonary haemorrhage and the risk of isolated pulmonary anti-GBM disease, empirical treatment with plasma exchange, intravenous methylprednisolone, and cyclophosphamide was commenced, while awaiting confirmatory testing. Clinicians should recognize that bovine bio-prostheses can induce cross-reactive antibodies, producing false-positive anti-GBM serology. Confirmatory testing and multidisciplinary correlation are essential."
Case report • Clinical • Glioblastoma • Glomerulonephritis • Immunology • Lupus Nephritis • Nephrology
March 20, 2026
THREE FACES OF RENAL COMPLEXITY: HORSESHOE KIDNEY, ANCA VASCULITIS AND FSGS
(ISN-WCN 2026)
- "The interstitium displayed a 35–40% lymphoplasmacytic infiltrate and >20% interstitial fibrosis/tubular atrophy.Immunofluorescence revealed a pauci-immune pattern.Final diagnosis: ANCA-associated pauci-immune crescentic glomerulonephritis with concomitant FSGS in a horseshoe kidney.Results Following biopsy confirmation, the patient received pulse methylprednisolone 500 mg IV daily for 3 days, followed by oral corticosteroids and rituximab 500 mg × 2 for induction. It underscores that congenital renal anomalies may predispose to or modify autoimmune glomerular disease via altered hemodynamics and ischemic stress.Percutaneous biopsy of HK, though technically demanding, is safe and essential for diagnostic accuracy. Long-term remission achieved with rituximab-based therapy after delayed recognition highlights the importance of early diagnosis and multidisciplinary management in complex renal pathology."
ANCA Vasculitis • Chronic Kidney Disease • Fibrosis • Focal Segmental Glomerulosclerosis • Glomerulonephritis • Interstitial Lung Disease • Lupus Nephritis • Pulmonary Disease • Vasculitis
March 20, 2026
SUBARACHNOID HEMORRHAGE AND CEREBRAL INFARCTION IN ANTI-GLOMERULAR BASEMENT MEMBRANE DISEASE: A CASE REPORT AND REVIEW OF THE LITERATURE
(ISN-WCN 2026)
- "Despite persistently elevated antibody titers refractory to corticosteroids and plasma exchange (PE), rituximab (RTX) induction achieved a stable and sustained decline in antibody levels.Methods A 53-year-old woman presented with fever, headache, and progressive renal dysfunction...She received intravenous methylprednisolone pulse followed by oral prednisolone and PE...The current standard treatment for anti-GBM disease includes PE, corticosteroids, and cyclophosphamide (CYC)...Clinicians should be alert to potential neurological involvement in anti-GBM disease. Furthermore, our case suggests that RTX may serve as a therapeutic option when conventional therapy fails to sufficiently reduce antibody titers."
Case report • Clinical • Review • Cardiovascular • Cerebral Hemorrhage • CNS Disorders • Epilepsy • Hypertension • Infectious Disease • Infertility • Nephrology • Renal Disease • Sexual Disorders • Subarachnoid Hemorrhage • CRP
March 20, 2026
MINIMAL CHANGE DISEASE AS A PARANEOPLASTIC MANIFESTATION OF BRCA1 MUTATION–POSITIVE FALLOPIAN TUBE CANCER: AN AUTOPSY CASE
(ISN-WCN 2026)
- "She received intravenous methylprednisolone (1 g/day for 3 days), followed by oral prednisolone (40 mg/day) and cyclosporine (100 mg/day).Results Despite combined corticosteroid and immunosuppressive therapy, nephrotic-range proteinuria persisted, and serum albumin levels remained markedly low. Genetic testing and risk-reducing salpingo-oophorectomy (RRSO) may help prevent such outcomes in BRCA1 mutation carriers. Early oncologic evaluation is essential when nephrotic syndrome fails to respond to standard immunosuppressive therapy."
Clinical • Breast Cancer • Congestive Heart Failure • Fallopian Tube Cancer • Glomerulonephritis • Gynecology • Heart Failure • Hematological Malignancies • Lymphoma • Oncology • Ovarian Cancer • Respiratory Diseases • BRCA1
March 20, 2026
PLASMA CELL RICH ACUTE REJECTION : A SILENT CULPRIT OF ACUTE ON CHRONIC GRAFT DYSFUNCTION.
(ISN-WCN 2026)
- "Treatment was started from 27.8.25 .Patient received intravenous methylprednisolone (500 mg/kg for 3 days) , anti-thymocyte globulin (1.5 mg/kg/day for 4 days) and 1 cycle of bortezomib (1.3 mg/m2 on days 1, 4, 8, and 11).Following the treatment her creatinine started coming down within 2 weeks to 1.4Conclusion Plasma cell rich acute rejection is classically taken as acute cell mediated rejection but very often there are features of acute antibody mediated rejection as well. To date, there is no gold standard for efficient treatment of PCAR. Reports suggest use of methyl prednisolone (500 mg/kg), 7 sessions of plasmapheresis, anti-thymocyte globulin (3–5 mg/kg/day for 10 days), rituximab (2 doses at 375 mg/m2), and bortezomib (1 cycle at 1.3 mg/m2), with 2-year graft survival rate after rejection of 90%."
Antibody-mediated Rejection • Infectious Disease • Inflammation • Nephrology • Transplant Rejection
March 20, 2026
COCAINE AND TUBULOINTERSTITIAL NEPHRITIS WITH ISOLATED ANA POSITIVITY: DRUG-INDUCED AUTOIMMUNITY OR LUPUS MIMICKER?
(ISN-WCN 2026)
- "Cocaine use, especially when adulterated with levamisole, has been linked to immunomodulatory agent known to trigger unusual autoimmune phenomena, even in the absence of classic lupus or ANCA-associated vasculitis criteria...The patient received three IV methylprednisolone pulses followed by a prednisone taper, without renal recovery...The absence of specific autoantibodies and immune deposits, combined with toxic exposure history, supports a drug-induced mechanism. Recognizing this diagnostic pattern is crucial to differentiate drug-induced injury from primary autoimmune disease and avoid misdiagnosis or overtreatment."
ANCA Vasculitis • Cardiovascular • Diabetes • Diabetic Nephropathy • Fibrosis • Glomerulonephritis • Heart Failure • Hematological Disorders • Hepatology • Human Immunodeficiency Virus • Immunology • Infectious Disease • Inflammatory Arthritis • Lupus • Metabolic Disorders • Nephrology • Ophthalmology • Peptic Ulcer • Type 2 Diabetes Mellitus • Vasculitis
March 20, 2026
BETWEEN TB AND TREATMENT: MODIFIED PONTICELLI RESCUE FOR RITUXIMAB RESISTANT PLA2R POSITIVE MEMBRANOUS NEPHROPATHY IN AN ADOLESCENT
(ISN-WCN 2026)
- "Modified Ponticelli initiated: alternating monthly cycles of (1) IV methylprednisolone 250mg×3 days then oral prednisolone 0.5mg/kg/day×27 days (months 1,3,5), and (2) oral cyclophosphamide 1.5mg/kg/day×30 days (months 2,4,6). Restoration of daily school attendance demonstrates meaningful quality-of-life impact. This case underscores conventional immunosuppression relevance when biologics fail and the importance of individualized treatment strategies which integrates efficacy, safety, accessibility, cost-effectiveness, and infectious disease screening in adolescent glomerular disease management."
Glomerulonephritis • Hematological Disorders • Infectious Disease • Renal Disease
March 20, 2026
SUCCESSFUL TREATMENT OF IMMUNOSUPPRESSIVE THERAPY AND LDL-APHERESIS FOR NEPHROTIC SYNDROME CAUSED BY FIBRONECTIN GLOMERULOPATHY DIAGNOSED BY IMMUNOSTAINING AND GENETIC ANALYSIS
(ISN-WCN 2026)
- "Treatment was initiated on the day of admission, starting with intravenous methylprednisolone (1000 mg/day for three days), followed by oral prednisolone...Cyclosporine was introduced as adjunctive therapy, and corticosteroids were gradually tapered...The patient has since maintained long-term remission.Results Although FNG is not considered to involve an immunologic mechanism, several reports have described cases without coexisting autoimmune disease that responded favorably to corticosteroids or combined immunosuppressive therapy, such as mycophenolate mofetil...In our case, the patient initially presented with refractory nephrotic syndrome and underwent LDL-A, which led to a mild improvement in serum albumin levels.Conclusion We report a rare case of FNG presenting with nephrotic syndrome that achieved remission through a combination of immunosuppressive therapy and LDL-A. Further accumulation of clinical evidence is needed to clarify the therapeutic efficacy and..."
Dyslipidemia • Glomerulonephritis • Immunology • Lupus Nephritis • Nephrology • Renal Disease • FN1
March 20, 2026
TRIPLE HIT NEPHROPATHY: A CASE OF ATYPICAL ANTI-GBM DISEASE WITH CONCURRENT MEMBRANEOUS NEPHROPATHY AND ANCA ASSOCIATED VASCULITIS
(ISN-WCN 2026)
- "Following recurrence of LCV, he was diagnosed with granulomatosis with polyangiitis and was started on prednisone and rituximab...He was treated with IV methylprednisolone, plasmapheresis and oral cyclophosphamide...Thus, ANCA could have been a priming factor in the evolution of overlapping immune-mediated glomerular injury.This case underscores the complex nature and plausible interaction of different auto-immune diseases. It also highlights the need for high clinical suspicion and thorough histopathologic evaluation in affected patients, as early identification of multifaceted immune injury may meaningfully influence outcomes.Conclusion Teaching PointsAtypical anti-GBM disease present with negative serology but classic linear IgG staining.ANCA vasculitis may precede or trigger anti-GBM autoimmunity through GBM antigen exposure.Concurrent membranous nephropathy with Anti-GBM disease suggests a biphasic glomerular injury exposing underlying GBM or podocyte antigens and..."
Clinical • ANCA Vasculitis • Glioblastoma • Glomerulonephritis • Lupus Nephritis • Nephrology • Rare Diseases • Renal Calculi • Renal Disease • Vasculitis • Vitiligo
March 20, 2026
PREDICTIVE FACTORS FOR GLUCOCORTICOID-FREE REMISSION IN LUPUS NEPHRITIS
(ISN-WCN 2026)
- "Compared with non-achievers, GC-free achievers more frequently received methylprednisolone intravenous pulses (HR 2.58, 95% CI 1.15–5.78, p = 0.0212) and hydroxychloroquine (HR 4.01, 95% CI 1.37–11.77, p = 0.0114), and were more likely to have tapered PSL to ≤ 7.5 mg/day at 12 months (HR 2.57, 95% CI 1.21–5.46, p = 0.0138).Conclusion Methylprednisolone intravenous pulses, concomitant hydroxychloroquine use, and tapering PSL to ≤ 7.5 mg/day within 12 months are associated with achieving GC-free remission in LN. These findings support the clinical feasibility of GC-free management in appropriately selected patients with LN."
Biomarker • Clinical • Glomerulonephritis • Immunology • Infectious Disease • Inflammatory Arthritis • Lupus • Lupus Nephritis • Nephrology
March 20, 2026
CXCL13 EXPRESSION IN THE LYMPH NODE AND KIDNEY OF A PATIENT WITH IDIOPATHIC MULTICENTRIC CASTLEMAN DISEASE WITH TAFRO SYNDROME
(ISN-WCN 2026)
- "Intravenous methylprednisolone (500 mg/day for 3 days) followed by oral prednisolone (60 mg/day, approximately 1 mg/kg/day) was started on hospital day 8...Proteinuria improved to 0.66 g/gCr two months after the initiation of tocilizumab.Conclusion Combination therapy with glucocorticoids and tocilizumab achieved clinical remission in iMCD-TAFRO with kidney involvement...(b) CXCL13 is positive in the glomerulus and tubules of the kidney. (c) CXCL13 is positive in the germinal centers of the lymph node."
Clinical • Glomerulonephritis • Hematological Disorders • Inflammation • Nephrology • Pulmonary Disease • Rare Diseases • Renal Disease • Thrombocytopenia • CXCL13
March 20, 2026
ATYPICAL IGA NEPHROPATHY UNMASKED BY IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME IN A HIV PATIENT
(ISN-WCN 2026)
- "However, IRIS leading to the unmasking of glomerular diseases is rarely reported.Methods A 42-year-old woman diagnosed with HIV presented with nausea and vomiting for 2 weeks, two months after starting highly active antiretroviral therapy (HAART) containing tenofovir disoproxil fumarate (TDF) 300 mg, lamivudine 300mg, and dolutegravir 50 mg...DIF studies showed mesangial IgA (3+), C3 (1+), and kappa (3+) staining and lambda (1+).Download: Download high-res image (868KB)Download: Download full-size imageResults She was treated with IV methylprednisolone 500 mg for 3 doses, followed by oral prednisolone at 0.5 mg/kg body weight. HAART was modified to an abacavir-based regimen...To conclude, this case emphasizes the need for clinicians to be aware of the diverse renal manifestations of IRIS in the setting of HIV. It also underscores the need for vigilance after initiating HAART."
Clinical • Glomerulonephritis • Human Immunodeficiency Virus • IgA Nephropathy • Immunology • Infectious Disease • Inflammatory Arthritis • Monoclonal Gammopathy • Renal Disease • CD4
March 20, 2026
UNBOXING A RARE LINK BETWEEN THE KIDNEYS AND THE LUNGS: REVERSAL OF INFECTION RELATED GLOMERULONEPHRITIS IN A PEDIATRIC PULMONARY TUBERCULOSIS PATIENT WITH CORTICOSTEROIDS
(ISN-WCN 2026)
- "He was then started on pulse iv steroid (methylprednisolone 500 mg iv once daily for 3 days) followed by oral wysolone 1 mg/kg/day...Even more rare is the presentation of dialysis requiring IRGN and these phenotype of patients' respond dramatically with steroids and treatment of the underlying cause, which in this case was anti tubercular therapy.Conclusion In conclusion, we present a rare case of immune mediated glomerulonephritis complicating pulmonary tuberculosis in an adolescent. Glomerulonephritis should be strongly considered in patients diagnosed with active tuberculosis who develop renal complications that appear unrelated to the primary focus of tuberculous infection since early initiation of immunosuppression in these patients can complete alter the renal course in these patients."
Clinical • Amyloidosis • Cardiovascular • Cough • Glomerulonephritis • Hypertension • IgA Nephropathy • Infectious Disease • Lupus Nephritis • Nephrology • Pediatrics • Respiratory Diseases • Tuberculosis
March 20, 2026
TOWARD IMMUNOSUPPRESSANT-FREE INDUCTION THERAPY FOR PROLIFERATIVE LUPUS NEPHRITIS: A TELITACICEPT-BASED CASE REPORT
(ISN-WCN 2026)
- "Introduction Conventional induction therapy for proliferative lupus nephritis (PLN) requires high-dose glucocorticoids combined with immunosuppressants (e.g., cyclophosphamide or mycophenolate), which carries substantial risks of infections, poor adherence, and gonadotoxicity – a critical concern for reproductive-age patients...Prior to admission, the patient received irbesartan (150 mg daily) for proteinuria management. During hospitalization, therapy was initiated with methylprednisolone (40 mg intravenously twice daily), hydroxychloroquine sulfate (200 mg orally twice daily), and telitacicept (160 mg subcutaneously weekly).Results Complete clinical remission, defined as resolution of edema and normalization of urinary protein excretion, was achieved within two months without reported adverse events.Conclusion This first reported case demonstrates the feasibility of immunosuppressant-free induction therapy with telitacicept in PLN. The rapid reduction in proteinuria..."
Case report • Clinical • Cough • Glomerulonephritis • Immunology • Infectious Disease • Inflammatory Arthritis • Lupus • Lupus Nephritis • Musculoskeletal Diseases • Musculoskeletal Pain • Nephrology • Orthopedics • Respiratory Diseases
March 20, 2026
A CASE OF POLYANGIITIS OVERLAP SYNDROME WITH MPO-ANCA–POSITIVE MICROSCOPIC POLYANGIITIS AND EOSINOPHILIC GRANULOMATOSIS WITH POLYANGIITIS
(ISN-WCN 2026)
- "She was treated with intravenous methylprednisolone 500 mg/day for 3 days, followed by oral prednisolone 30 mg/day (0.6 mg/kg)...Conclusion Previous reports of MPO-ANCA-positive POS generally describe modest ANCA titers and require combined immunosuppressive therapy for remission. In contrast, our patient achieved rapid remission with corticosteroid monotherapy despite extremely high MPO-ANCA levels. The absence of peripheral neuropathy and lack of serum interleukin-5 elevation, coupled with the presence of interstitial pneumonia, were atypical for EGPA."
Clinical • Diabetes • Eosinophilic Granulomatosis With Polyangiitis • Glomerulonephritis • Immunology • Infectious Disease • Inflammation • Interstitial Lung Disease • Langerhans Cell Histiocytosis • Lupus Nephritis • Metabolic Disorders • Musculoskeletal Pain • Nephrology • Peripheral Neuropathic Pain • Pneumonia • Pulmonary Disease • Rare Diseases • Renal Disease • Respiratory Diseases • Retinal Disorders • Type 2 Diabetes Mellitus • Vasculitis • IL5 • MPO
March 20, 2026
COST AND HEALTHCARE RESOURCE USE IN PATIENTS WITH IGA NEPHROPATHY: A SYSTEMATIC LITERATURE REVIEW
(ISN-WCN 2026)
- "A mean LoS of 11.4 days was reported in Japanese patients who underwent tonsillectomy followed by intravenous methylprednisolone.Cost data was reported in 13 studies...A Japanese study reported higher work time missed and work impairment in patients with proteinuria >=1 g/d (19.9% and 37.5%) vs. patients with proteinuria <1 g/day (3.5% and 15.3%). A cost comparison across the US and the UK is provided in table 1, which revealed that emergency and outpatient visit costs were significantly higher in the US compared to the UK.Download: Download high-res image (301KB)Download: Download full-size imageConclusion IgAN significantly increases healthcare costs and resource use, especially with disease progression and higher proteinuria.I have potential conflict of interest to disclose.All authors of this abstract are employees of Novartis Pharma AG.I did not use generative AI and AI-assisted technologies in the writing process."
Clinical • Review • Chronic Kidney Disease • Glomerulonephritis • IgA Nephropathy • Infectious Disease • Renal Disease
March 20, 2026
IMMUNOSUPPRESSIVE THERAPY IN IGA NEPHROPATHY ASSOCIATED WITH CHRONIC LIVER DISEASE
(ISN-WCN 2026)
- "Thirty-seven patients received immunosuppression (IV solumedrol, oral steroids, and mycophenolate mofetil), while 23 received conservative management. In the IMM group, one patient died of sepsis with hepatic encephalopathy, and another had recurrent SBP requiring early IMM termination.Conclusion Immunosuppression in CLD-associated IgAN significantly improves renal outcomes without accelerating liver dysfunction. While infections and decompensation risks require close monitoring, these findings challenge the conventional wisdom of avoiding immunosuppression and excluding these patients from clinical trials"
Cardiovascular • CNS Disorders • Glomerulonephritis • Hepatic Encephalopathy • Hepatology • Hypertension • IgA Nephropathy • Infectious Disease • Liver Failure • Renal Disease • Septic Shock
March 20, 2026
ACUTE KIDNEY INJURY REQUIRING HEMODIALYSIS AS THE FIRST CLINICAL MANIFESTATION OF PAROXYSMAL NOCTURNAL HEMOGLOBINURIA IN A 20-YEAR-OLD PATIENT, CASE REPORT.
(ISN-WCN 2026)
- "The patient underwent 4 hemodialysis sessions and received pulse therapy with methylprednisolone 1g IV for 3 days followed by prednisone with a gradual reduction until discontinuation in August 2025. Given the persistent hemolysis, the possibility of paroxysmal nocturnal hemoglobinuria was considered and flow cytometry for PNH was performed, which confirmed the diagnosis. The patient was referred to a hematologist and a complement blocker was started in August 2025.Conclusion The diagnosis of PNH as an AKI phenotype is challenging and this case reinforces that it is always important to identify the mechanism of acute kidney injury, as it allows for earlier and more assertive treatment."
Case report • Clinical • Acute Kidney Injury • Cardiovascular • Complement-mediated Rare Disorders • Dyslipidemia • Glomerulonephritis • Hematological Disorders • Hepatitis B • Hepatology • Human Immunodeficiency Virus • Immunology • Infectious Disease • Inflammation • Metabolic Disorders • Nephrology • Paroxysmal Nocturnal Hemoglobinuria • Rare Diseases • Renal Disease • Thrombocytopenia • Thrombosis • HP
March 20, 2026
A RARE CASE OF CONCURRENT ANTI-GLOMERULAR BASEMENT MEMBRANE NEPHRITIS AND MEMBRANOUS NEPHROPATHY WITH POSITIVE ANCA
(ISN-WCN 2026)
- "Intravenous methylprednisolone pulse therapy (500mg/body x 3 days) , followed by oral prednisolone (1 mg/kg/day), was administered...The coexistence of anti–GBM nephritis and MN with MPO-ANCA positivity is exceptionally uncommon, and the clinical relevance of this association warrant further investigation. This work was first presented at ASN Kidney Week 2025, and re-submission is permitted by ASN."
Clinical • ANCA Vasculitis • Anorexia • Glomerulonephritis • Hematological Disorders • Infectious Disease • Interstitial Lung Disease • Lupus Nephritis • Nephrology • Pneumonia • Renal Disease • Respiratory Diseases • Vasculitis • EXT1 • MPO • NELL1
March 20, 2026
RAPIDLY PROGRESSIVE IGA NEPHROPATHY IN A PATIENT WITH A HISTORY OF BREAST CANCER: A CASE REPORT AND LITERATURE REVIEW
(ISN-WCN 2026)
- "The patient was treated with intravenous methylprednisolone (500 mg/day for 3 days), followed by oral prednisone (1 mg/kg/day) and intravenous cyclophosphamide every 15 days for 3 months according to a rapidly progressive glomerulonephritis protocol (0.5 g/m2). Although the pathogenetic link remains uncertain, tumor-related immune dysregulation or chemotherapy-induced mechanisms could have contributed to the glomerular injury. Clinicians should maintain a high index of suspicion for glomerular disease in cancer patients with hematuria or acute renal dysfunction, even during remission."
Case report • Clinical • Review • Breast Cancer • Glomerulonephritis • Hepatitis B • Hepatitis C • Hepatology • Human Immunodeficiency Virus • Hypertension • IgA Nephropathy • Immunology • Infectious Disease • Lupus Nephritis • Oncology • Renal Disease • Solid Tumor
March 20, 2026
IMMUNOGLOBULIN A NEPHROPATHY WITH MINIMAL CHANGE DISEASE OVERLAP PRESENTING AS ACUTE KIDNEY INJURY REQUIRING HEMODIALYSIS
(ISN-WCN 2026)
- "Because nephrotic-range proteinuria remained, repeated courses of intravenous methylprednisolone were administered, and a calcineurin inhibitor was added...These findings suggest that risk assessment and management strategies established for AKI in MCD should also be applied to patients with MCD-IgAN.Conclusion MCD-IgAN can present with severe AKI requiring RRT. Careful acute-phase management with attention to AKI risk is important even in this generally favorable phenotype."
Acute Kidney Injury • Cardiovascular • Dyslipidemia • Glomerulonephritis • Hypertension • IgA Nephropathy • Nephrology • Renal Disease
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