MSB-0221 / MatriSys Bio - LARVOL DELTA

Unveiling the molecular basis of arsenic resistance in Dietzia maris isolated from arsenic-contaminated soil. (PubMed, BMC Biotechnol) - "Collectively, these observations proved D. maris strain sha9 is a metabolically adaptable and genetically equipped arsenite-oxidizing bacterium with robust capability for arsenic bioremediation from contaminated sites."

Journal • CAT

Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2) (clinicaltrials.gov) - P1 | N=86 | Recruiting | Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) | Phase classification: P1/2 ➔ P1 | Trial completion date: Nov 2026 ➔ Feb 2027

Phase classification • Trial completion date • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Skin Environmental and Microbial Crosstalk in AD Pathogenesis (ISAD-RAJKA 2025) - "Clinical research on targeted interventions using single bacterial strains is also advancing, including studies on ShA9, FB-401 (a consortium of three R. mucosa strains), and Nitrosomonas eutropha B244 (an ammonia-oxidizing bacterium). However, the mechanisms affect the microbiota are still under active investigation. Drawing on our research findings, we will provide a brief overview integrating the above aspects."

Atopic Dermatitis • Dermatitis • Dermatology • Immunology • Inflammation • Pruritus

Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2) (clinicaltrials.gov) - P1/2 | N=86 | Recruiting | Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) | Not yet recruiting ➔ Recruiting | Phase classification: P2 ➔ P1/2 | Trial completion date: Jul 2026 ➔ Nov 2026 | Trial primary completion date: Jun 2026 ➔ Oct 2026

Enrollment open • Phase classification • Trial completion date • Trial primary completion date • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2) (clinicaltrials.gov) - P2 | N=86 | Not yet recruiting | Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) | Trial completion date: Apr 2026 ➔ Jul 2026 | Trial primary completion date: Mar 2026 ➔ Jun 2026

Trial completion date • Trial primary completion date • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2) (clinicaltrials.gov) - P2 | N=86 | Not yet recruiting | Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) | Initiation date: Sep 2024 ➔ Dec 2024

Trial initiation date • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2) (clinicaltrials.gov) - P2 | N=86 | Not yet recruiting | Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

New P2 trial • Atopic Dermatitis • Dermatitis • Dermatology • Immunology