MSB-0221 / MatriSys Bio - LARVOL DELTA

Skin Environmental and Microbial Crosstalk in AD Pathogenesis (ISAD-RAJKA 2025) - "Clinical research on targeted interventions using single bacterial strains is also advancing, including studies on ShA9, FB-401 (a consortium of three R. mucosa strains), and Nitrosomonas eutropha B244 (an ammonia-oxidizing bacterium). However, the mechanisms affect the microbiota are still under active investigation. Drawing on our research findings, we will provide a brief overview integrating the above aspects."

Atopic Dermatitis • Dermatitis • Dermatology • Immunology • Inflammation • Pruritus

Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2) (clinicaltrials.gov) - P1/2 | N=86 | Recruiting | Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) | Not yet recruiting ➔ Recruiting | Phase classification: P2 ➔ P1/2 | Trial completion date: Jul 2026 ➔ Nov 2026 | Trial primary completion date: Jun 2026 ➔ Oct 2026

Enrollment open • Phase classification • Trial completion date • Trial primary completion date • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2) (clinicaltrials.gov) - P2 | N=86 | Not yet recruiting | Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) | Trial completion date: Apr 2026 ➔ Jul 2026 | Trial primary completion date: Mar 2026 ➔ Jun 2026

Trial completion date • Trial primary completion date • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2) (clinicaltrials.gov) - P2 | N=86 | Not yet recruiting | Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) | Initiation date: Sep 2024 ➔ Dec 2024

Trial initiation date • Atopic Dermatitis • Dermatitis • Dermatology • Immunology

Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2) (clinicaltrials.gov) - P2 | N=86 | Not yet recruiting | Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

New P2 trial • Atopic Dermatitis • Dermatitis • Dermatology • Immunology