gentamicin sulfate / Generic mfg. - LARVOL DELTA

Coinfection meningitis caused by Lysinibacillus sphaericus and Brevundimonas diminuta in a pediatric patient with cerebral atrophy: a case report. (PubMed, J Med Case Rep) - "This case highlights that even immunocompetent hosts with indwelling neurological devices are susceptible to opportunistic infections by environmental pathogens. Molecular diagnostic techniques are crucial for confirming rare pathogens, and intrathecal administration can serve as a vital adjunctive strategy when systemic therapy is ineffective."

Journal • CNS Disorders • Infectious Disease • Pediatrics

Study of extended-spectrum beta-lactamases and AmpC beta-lactamases producing Klebsiella from clinical samples in tertiary care hospital of Punjab. (PubMed, World J Virol) - "Klebsiella species are significant nosocomial and opportunistic pathogens characterized by high multidrug resistance, often through the production of extended-spectrum and AmpC beta-lactamases. Surveillance, confirmatory testing, and infection control guide antibiotic use and prevent spread."

Journal • Infectious Disease • Pneumonia

BIGG: Intra-nodal Injection of Gentamicin for the Treatment of Suppurated Cat Scratch Disease's Lymphadenitis (clinicaltrials.gov) - P3 | N=75 | Completed | Sponsor: University Hospital, Toulouse | Recruiting ➔ Completed | Trial completion date: Dec 2025 ➔ Aug 2025 | Trial primary completion date: Dec 2025 ➔ Aug 2025

Trial completion • Trial completion date • Trial primary completion date

ANTIMICROBIAL SENSITIVITY PATTERNS OF URINARY TRACT INFECTION AMONG SUDANESE CHILDREN WITH CONGENITAL ANOMALIES OF KIDNEY AND URINARY TRACT (CAKUT) (ISN-WCN 2026) - "Which was sensitive to ciprofloxacin and amikacin but resistant to ceftazidime and gentamicin. UTIs are highly prevalent in CAKUT patients, particularly those with bladder and urethral anomalies. Antibiotic sensitivity varies, highlighting the importance of appropriate antimicrobial selection."

Clinical • Infectious Disease • Nephrology

CASE REPORT : PERITONEAL DIALYSIS-ASSOCIATED PERITONITIS DUE TO S. AUREUS VS P. AERUGINOSA IN DIFFERENT PATIENTS (ISN-WCN 2026) - "We gave 14 days of ip ceftriaxone and gentamycin, followed by oral ciprofloxacin for 7 days to patient one...On patient two, after 5 days of being given ip ceftazidime and gentamycin, he showed refractory response. When comparing MSSA with P. aeruginosa peritonitis in CAPD patients, Pseudomonas is associated with a significantly worse prognosis. It leads to higher rates of treatment failure, catheter removal, and transfer to HD."

Case report • Clinical • Infectious Disease

SUCCESSFUL SALVAGE OF A PERITONEAL DIALYSIS CATHETER IN A CASE OF NONTUBERCULOUS MYCOBACTERIAL INFECTION (ISN-WCN 2026) - "Despite topical gentamicin, the discharge worsened. On Day -8, ultrasound showed a peri-catheter hypoechoic area consistent with TI, a swab for culture was obtained, and oral cefaclor was started...Empiric therapy with linezolid, amikacin, and clarithromycin was started on Day 1...Current guidance highlights NTM among atypical causes of refractory ESI, encourages individualized salvage strategies including exit-site relocationConclusion In PD patients with refractory ESI/TI, clinicians should obtain early AFB cultures and species identification to guide management. Early exit-site revision/debridement with an oral dual regimen of clarithromycin and sitafloxacin can salvage the catheter and maintain PD when cardiac dysfunction and obesity limit alternatives, demonstrating a practicalt success where evidence remains limited."

Clinical • Nontuberculous mycobacteria • Cardiovascular • Genetic Disorders • Heart Failure • Hematological Disorders • Infectious Disease • Nontuberculous Mycobacterial Disease • Obesity • Respiratory Diseases • Thrombocytopenia

A CASE OF PERITONEAL DIALYSIS ASSOCIATED PERITONITIS CAUSED BY STREPTOCOCCUS SALIVARIUS TWO MONTHS AFTER INGUINAL HERNIA REPAIR (ISN-WCN 2026) - "Treatment with gentamicin ointment and oral cefalexin 500 mg resulted in resolution of the granulation tissue four weeks post-surgery...Treatment was initiated with intraperitoneal administration of cefazolin 1 g + ceftazidime 1.5 g. Fever resolved on the second day of illness, and ascites fluid turbidity decreased.Conclusion The causative organism in this case, Streptococcus salivarius, is a normal flora bacterium in the oral cavity...Additionally, conversation during the connection procedure and failure to wear a mask were observed, raising the possibility of exogenous infection via touch contamination. Therefore, guidance on aseptic technique was reiterated."

Clinical • Dental Disorders • Gastroenterology • Infectious Disease • Nephrology • Periodontitis • Renal Disease

MANAGEMENT CHALLENGES IN MEDULLARY SPONGE KIDNEY COMPLICATED BY RHEUMATOID ARTHRITIS AND RECURRENT URINARY TRACT INFECTIONS: A CASE REPORT (ISN-WCN 2026) - "Management becomes challenging when immunosuppression, antimicrobial resistance, and drug allergies limit therapeutic options.Methods A woman in her 60s with rheumatoid arthritis, controlled on sulfasalazine 1,000 mg/day and subcutaneous tocilizumab 162 mg every 2 weeks, was diagnosed with MSK in her 40s after pyelonephritis and diffuse medullary calcifications on non-contrast CT...Urine cultures repeatedly yielded multidrug-resistant Escherichia coli resistant to ampicillin, levofloxacin, and trimethoprim–sulfamethoxazole...Joint symptoms remained under control following the single tocilizumab dose.Conclusion In cases of MSK complicated by immunosuppression, recurrent UTIs may require tailored, stepwise regimens and careful antimicrobial stewardship when resistance and allergies constrain options. A strategic selection and sequencing of agents, including cephalexin (dosage adjusted for body weight), gentamicin, and fosfomycin calcium 9 g/day, was instrumental in..."

Case report • Clinical • Immunology • Infectious Disease • Inflammatory Arthritis • Musculoskeletal Pain • Nephrology • Rheumatoid Arthritis • Rheumatology

ANTIMICROBIAL SENSITIVITY PATTERNS OF URINARY TRACT INFECTION AMONG SUDANSES CHILDREN WITH CONGENITAL ANOMALIES OF KIDNEY AND URINARY TRACT (CAKUT) (ISN-WCN 2026) - "Positive urine cultures were found in 70% of patients, with Pseudomonas aeruginosa as the most common organism (37.1%),which was sensitive to ciprofloxacin and amikacin but resistant to ceftazidime and gentamicin. UTIs are highly prevalent in CAKUT patients, particularly those with bladder and urethral anomalies. Antibiotic sensitivity varies, highlighting the importance of appropriate antimicrobial selection."

Clinical • Infectious Disease • Nephrology

INFECTIVE ENDOCARDITIS IN HEMODIALYSIS PATIENTS: A REPORT OF TWO CASES ASSOCIATED WITH HEMODIALYSIS ACCESS (ISN-WCN 2026) - "Microbiology: Culture of the catheter tip revealed Methicillin-resistant Staphylococcus epidermidis (MRSE), which was resistant to vancomycin...Management: DLC removal and administration of intravenous ampicillin-sulbactam and gentamicin.Case II: A 57-year-old man with renal failure undergoing HD was admitted with worsening shortness of breath and decreased consciousness (GCS E3V4M2) and a body temperature of 38.7°C...The first case involved a 30-year-old woman and the second a 57-year-old man. Both cases met the Modified Duke Criteria."

Clinical • Cardiovascular • Infectious Disease • Inflammation • Renal Disease

COMPARISON OF FOUR DIFFERENT GENTAMICIN DOSING GUIDELINES FOR PEDIATRIC PATIENTS: VIRTUAL POPULATION INSIGHTS (ISN-WCN 2026) - "Drug exposure varies markedly across age groups, reflecting post-natal renal maturation; a factor not fully accounted for in current national dosing guidelines. Harmonizing dosing guidelines to consider renal maturation could reduce nephrotoxicity and optimize therapeutic outcomes in pediatric care.I have potential conflict of interest to disclose.Felix J. Meigel and Doris H. Fuertinger are employees of Fresenius Medical Care Deutschland GmbH.I did not use generative AI and AI-assisted technologies in the writing process."

Clinical • Infectious Disease • Pediatrics

Analysis of Pharmacist Interventions to Reduce Medication-Related Problems in a Neonatal Clinical Care Unit. (PubMed, Pharmacy (Basel)) - "343/873, 39.3% of interventions documented were from the Neonatal Intensive Care Unit, involving medications such as gentamicin (n = 46/343, 13.4%), benzylpenicillin (n = 37/343, 10.8%), caffeine (n = 34/343, 9.9%), parenteral nutrition (n = 23/343, 6.7%), and morphine (n = 16/343, 4.7%) and meropenem (n = 16/343, 4.7%)). (4) Regular analysis of pharmacist interventions provides valuable insights into local MRP trends and highlights opportunities for quality improvement and education."

Journal • Critical care

Molecular insights into antimicrobial resistance and virulence in hospital-associated of vancomycin-resistant Enterococcus faecium isolates in a tertiary hospital in Bangkok Thailand. (PubMed, PLoS One) - "All isolates exhibited resistance to penicillin, ampicillin, vancomycin, levofloxacin, ciprofloxacin, and rifampin. Resistance to erythromycin, high-level streptomycin, teicoplanin, and tetracycline occurred in 98.1%, 53.8%, 51.9%, and 17.3% of isolates, respectively. Chloramphenicol, linezolid, and high-level gentamicin remained effective against all isolates...Genome analysis reveals antibiotic resistance genes, virulence factors, and mobile genetic elements that may drive antimicrobial resistance, increase diversity, and support adaptation in hospital settings. Ongoing infection control and active surveillance are essential."

Journal • Infectious Disease

Endovascular aneurysm repair combined with local and systemic antibacterial treatment for infected aorto-iliac artery aneurysms caused by Brucella. (PubMed, BMC Infect Dis) - No abstract available

Journal • Cardiovascular

Detection of Finegoldia magna in Cyst Secretions from a Non-Lutating Female Breast: A Case Report. (PubMed, Infect Drug Resist) - "In vitro drug susceptibility testing showed that the strain was susceptible to penicillin, ampicillin, ceftriaxone, and imipenem, but resistant to clindamycin. The empyema cavity was irrigated with gentamicin saline, and local dressing changes were performed, leading to good wound healing and discharge. This case suggests that clinicians should pay attention to the possibility of anaerobic bacterial infections after breast surgery, especially when routine bacterial cultures are negative, necessitating timely anaerobic culture. Combined with mass spectrometry identification and drug susceptibility test results, this approach guides precise treatment."

Journal • Infectious Disease

Capsular polysaccharides of Acinetobacter baumannii modulate antimicrobial resistance and innate immune response. (PubMed, Sci Rep) - "CPS-deficient mutant (∆galU) displayed increased susceptibility to gentamicin, tetracycline, colistin, and sodium dodecyl sulfate (SDS). Moreover, purified CPS induced pro-inflammatory cytokine expression in sterile infection and promoted neutrophil chemotaxis. Altogether, this study demonstrates that CPS not only mask A. baumannii virulence surface structures, but also actively modulate host immune response and antimicrobial resistance."

Journal • Infectious Disease • Inflammation • CASP3

The Impact of Pharmaceutical Care on Infection Control Measures Among Hemodialysis Patients. A Randomized Interventional Study. (PubMed, Int J Nephrol Renovasc Dis) - "The care bundle comprised culture-guided antibiotic locks (except gentamicin-heparin), in-hospital exit-site dressing with 3M Tegaderm by trained staff, and safety medication checks (e.g, blood-pressure monitoring before the use of erythropoiesis-stimulating agents) were used...The mean differences increased over time, reaching 0.26 (95% CI of diff.= 0.09 to 0.43) at visit 1, 0.41 (95% CI of diff.= 0.24 to 0.58) at visit 3, and 0.51 (95% CI of diff.= 0.34 to 0.68) at visit 4. Clinical pharmacist intervention via implementing infection control within the context of a pharmaceutical-care process can improve infection rates among hemodialysis patients."

Clinical • Journal • Cardiovascular • Infectious Disease • Renal Disease

A five-step infection control bundle for the permanent containment of a ceftriaxone-susceptible but gentamicin- and piperacillin/tazobactam-non-susceptible hypervirulent ST39 Klebsiella pneumoniae outbreak in a neonatal intensive care unit (NICU) (ESCMID Global 2026) - No abstract available

Critical care • Infectious Disease • Pneumonia

Empiric vancomycin and gentamicin for peritoneal dialysis peritonitis: are we still on target? (ESCMID Global 2026) - No abstract available

Transient benefit of intravesical gentamicin instillation for recurrent urinary tract infections in a complex urological cohort (ESCMID Global 2026) - No abstract available

Infectious Disease • Nephrology

"No breakpoints? no problem!" evaluating gentamicin perioperative prophylaxis for Pseudomonas aeruginosa asymptomatic bacteriuria before urological surgery (ESCMID Global 2026) - No abstract available

Surgery

Microdialysis Assessment of Gentamicin for Second-Line Antimicrobial Prophylaxis in Abdominal Surgery (ESCMID Global 2026) - No abstract available

Clinical • Surgery

Listeria Monocytogenes: A Case Series and Clinical Insights from a Tertiary Care Hospital. (PubMed, J Pharm Bioallied Sci) - "The organisms were all gentamicin and ampicillin-sensitive. The series reiterates the importance of maintaining listeriosis as a significant concern in febrile patients with predisposing conditions. Early diagnosis and early treatment with appropriate antibiotics have positive outcomes."

Journal • Chronic Kidney Disease • CNS Disorders • Diabetes • Infectious Disease • Metabolic Disorders • Nephrology • Oncology • Renal Disease

Microbial contamination of ART culture media with Enterococcus faecalis: case report of a live birth following blastocyst transfer. (PubMed, Reprod Biomed Online) - "Treatment with prophylactic amoxicillin resulted in a healthy live birth from a blastocyst contaminated with E. faecalis, questioning the systematic discarding of embryos from contaminated culture medium."

Journal

Ménière's Disease: Treatment Options, Dietary Restrictions, and Lifestyle Modifications. (PubMed, J Pharm Bioallied Sci) - "This review aims to review treatments and studies for Ménière's disease (MD) and the impact of dietary restrictions and lifestyle changes on MD symptoms."

Journal • Review • Otorhinolaryngology • Vertigo