Hu002-MMAE / Shanghai Pharma - LARVOL DELTA

Potent Anti-Tumor Activity Demonstrated by Anti-AXL CAR T Cell Therapy and AXL-ADC in Lung Cancer and Breast Cancer Models (AACR 2024) - "We created a novel a novel AXL-ADC (Hu002-MMAE) based on humanized AXL-targeted antibody (Hu002)... Anti-AXL CAR T and AXL-ADC cells showed strong and selective killing activity, improved TME in primary tumor and mitigate lung metastasis, which makes it a potential strategy for cancers."

ADC • CAR T-Cell Therapy • IO biomarker • Late-breaking abstract • Preclinical • Brain Cancer • Breast Cancer • CNS Tumor • Glioma • Lung Cancer • Non Small Cell Lung Cancer • Oncology • Solid Tumor • AXL