NT-506 / Neurotech Pharma - LARVOL DELTA

Cloning, expression and biochemical characterization of recombinant superoxide dismutase from Antarctic psychrophilic bacterium Pseudoalteromonas sp. ANT506. (PubMed) - "rPsSOD exhibited well capability to 2.5 M NaCl (62.4%). These results indicated that rPsSOD exhibited special catalytic properties."

Journal • Biosimilar

High-Intensity 10-s Work: 5-s Recovery Intermittent Training Improves Anaerobic and Aerobic Performances. (PubMed, Res Q Exerc Sport) - "RAMP peak PO and V̇O increased within both groups (INT 341 ± 63 to 370 ± 48 W, p = .002, Cd = 0.52; HICT 332 ± 45 to 353 ± 44 W, p = .006, Cd = .53; 3.73 ± 0.68 to 4.06 ± 0.63 L·min, p = .001, Cd = .50; 3.75 ± 0.62 to 4.09 ± 0.52 L·min, p = .002, Cd = .59). Conclusion(s): These results show that utilizing this novel short work: shorter rest (10 s: 5 s) interval training paradigm will elicit better performances in moderate duration performances compared to continuous training of the same duration, effort, and frequency."

Journal

Cost-effectiveness of Hepatitis A vaccination in a developed and developing country. (PubMed, Int J Health Care Qual Assur) - "This analysis showed universal vaccination to be cost-effective as compared to no vaccination, and portions of the study's approach had not previously been applied in tandem to investigate Hepatitis A interventions. The results may help foster higher compliance rates for Hepatitis A vaccination and even greater per-person economic benefits of universal vaccination, particularly in the USA. The purpose of this study is also to encourage elevated levels of surveillance on age of infection in developing regions and consistent reevaluation utilizing dynamic transmission models in both the USA and Brazil, as well as other rapidly developing regions, in order to prevent future epidemics and costs associated with the disease."

HEOR • Journal

Drug utilisation among Dutch adolescents: a pharmacy prescription records study. (PubMed, Arch Dis Child) - "These insights into adolescent drug use help us to better understand adolescent healthcare use."

Journal

The impact of community- versus clinic-based adherence clubs on loss from care and viral suppression for antiretroviral therapy patients: Findings from a pragmatic randomized controlled trial in South Africa. (PubMed, PLoS Med) - "These findings demonstrate that overall loss from an adherence club intervention was high in this setting and that, importantly, it was worse in community-based adherence clubs compared to those based at the clinic. We urge caution in assuming that the effectiveness of clinic-based interventions will carry over to community settings, without a better understanding of patient-level factors associated with successful retention in care."

Clinical • Journal