Undisclosed rheumatoid arthritis therapeutic
/ Istesso
- LARVOL DELTA
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March 27, 2021
[VIRTUAL] Clinical Risk Factors for Osteoporotic Fractures in Men With Non-Metastatic Prostate Cancer on Androgen Deprivation Therapy With or Without Anti-Osteoporosis Treatment
(ENDO 2021)
- "Anti-OsteoRx included bisphosphonates, denosumab, and parathyroid hormone analogs. OsteoFx risk assessment utilizing CRF, FRAX, DXA with timely intervention may prevent OsteoFx in these high-risk patients. Unless otherwise noted, all poster abstracts presented at ENDO 2021 are embargoed until 11 AM Eastern on Saturday, March 20. For oral presentations, the abstracts are embargoed until the session begins."
Clinical • Diabetes • Genito-urinary Cancer • Metabolic Disorders • Musculoskeletal Diseases • Oncology • Osteoporosis • Prostate Cancer • Rheumatology • Solid Tumor
March 27, 2021
[VIRTUAL] Fracture Rates in Men With Non-Metastatic Prostate Cancer on Androgen Deprivation Therapy With or Without Anti-Osteoporosis Treatment
(ENDO 2021)
- "Anti-OsteoRx included bisphosphonates, denosumab, and parathyroid hormone analogs. Fracture rate subgroups: • ADT only - Anti-OsteoRx 37/ 374 fractured (9.89%) • ADT only + Anti-OsteoRx 10/52 fractured (19.23%) • ADT + SupplRx + Anti-OsteoRx 2/19 fractured (10.53%) • ADT + SupplRx + Anti-OsteoRx 13/170 fractured (7.65%) Comparing fracture rates between subgroups: • Comparing ADT only +/- Anti-OsteoRx, statistical significance was observed with higher fracture rate in patients taking Anti-OsteoRx (19.23% vs. 9.89%, p < 0.044) • Comparing ADT + SupplRx +/- Anti-OsteoRx, no significant difference in fracture rates due to small number of fractures Comparing combined subgroups: • ADT +/- SupplRx + Anti-OsteoRx 12/71 (16.9%) fractured • ADT +/- SupplRx - Anti-OsteoRx 50/544 (9.19%) fractured • Statistically significant between groups fracture rates was observed (p= 0.042) in patients treated with Anti-OsteoRX Patients receiving Anti-OsteoRx, regardless of their prostate..."
Genito-urinary Cancer • Musculoskeletal Diseases • Oncology • Osteoporosis • Prostate Cancer • Rheumatology • Solid Tumor
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