Omr-IgG-am (intravenous normal human immunoglobulin) / J&J - LARVOL DELTA

Is Intravenous Immunoglobulin Effective in Reducing the Risk of Mortality and Morbidity in Neuroinvasive West Nile Virus Infection? A Critically Appraised Topic. (PubMed, Neurologist) - "The appraised trial showed that Omr-IgG-am and Polygam are as safe as NS. Data on efficacy from this trial were limited by a small sample size. Phase III clinical trials on IVIG efficacy in NiWNV infection are needed."

Journal • Infectious Disease

Lack of Efficacy of High-Titered Immunoglobulin in Patients with West Nile Virus Central Nervous System Disease. (PubMed, Emerg Infect Dis) - "The death rate in the study population was 12.9%. No significant differences were found between groups receiving Omr-IgG-am compared with IVIG or saline for either the safety or efficacy endpoints."

Clinical • Journal

Intravenous immunoglobulins for rheumatic disorders and thromboembolic events-a case series and review of the literature. (PubMed, Immunol Res) - "...Nine patients who had suffered a thromboembolic event within a week after receiving an intravenous immunoglobulin infusion (Omr-IgG-am™, OMRIX) were identified among our joint cohort...No correlation was found between the number and frequency of the infusions to the thromboembolic events. Heightened awareness of possible thromboembolic events in rheumatic patients is encouraged for at least a week following IVIG administration."

Clinical • Journal