DS-3078 / Daiichi Sankyo - LARVOL DELTA

Small molecule CDS-3078 induces G/M phase arrest and mitochondria-mediated apoptosis in HeLa cells. (PubMed, Exp Ther Med) - "Therefore, CDS-3078 administration induced apoptosis via p53-mediated cell cycle arrest, causing mitochondrial dysfunction and resulting in apoptotic cell death in cervical cancer cells. Collectively, the present results suggested that CDS-3078 may be a potential anticancer agent."

IO Biomarker • Journal • Cervical Cancer • Metabolic Disorders • Oncology • Solid Tumor • BCL2