NG25
/ Dana-Farber Cancer Institute, Harvard Medical School
- LARVOL DELTA
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April 19, 2026
TAK1 inhibition restores p53 expression and suppresses inflammation and hyperplasia in juvenile idiopathic arthritis synovial fibroblasts.
(PubMed, Rheumatology (Oxford))
- "TAK1 inhibition restores p53 functions in JIASFs and downregulates synovial inflammation, which warrants further studies that target TAK1 to treat JIA."
Journal • Idiopathic Arthritis • Immunology • Inflammation • Rheumatology • CDH1 • CDKN1A • CXCL5 • CXCL8 • IFNG • IL1B • IL6 • MMP3 • PCNA • TGFB1 • TNFA • VCAM1
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