IDE574
/ Ideaya Biosci
- LARVOL DELTA
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December 10, 2025
IDEAYA Biosciences Announces IND Submission for IDE574, a Potential First-In-Class KAT6/7 Dual Inhibitor for Breast and Lung Cancers
(PRNewswire)
- "The company is targeting to begin a Phase 1 dose escalation trial of monotherapy IDE574 in the first quarter of 2026....IND-enabling studies support the potential clinical evaluation of IDE574 monotherapy in patients with hormone receptor-positive breast cancer, lung adenocarcinoma as well as additional opportunities associated with lineage addiction. IDEAYA is targeting to share data from its preclinical work with IDE574 at a medical conference in the first half of 2026."
IND • New P1 trial • Preclinical • Hormone Receptor Positive Breast Cancer • Lung Adenocarcinoma
November 04, 2025
In the fourth quarter IDEAYA submitted an IND for IDE034, a potential first-in-class B7H3/PTK7 bispecific TOP1i ADC, and is on track to file an IND for IDE574, a potential first-in-class KAT6/7 dual inhibitor, by the end of the year.
(PRNewswire)
IND • Solid Tumor
May 06, 2025
IDEAYA Biosciences, Inc. Reports First Quarter 2025 Financial Results and Provides Business Update
(PRNewswire)
- "IDE892: a potential best-in-class MTA-cooperative PRMT5 inhibitor to enable wholly-owned combination with IDE397. IND filing targeted for mid-year 2025....IDE034: a potential first-in-class B7H3/PTK7 TOP1i bispecific ADC with combination potential with IDE161. IND filing targeted for the second half of 2025. IDE574: a potential first-in-class KAT6/7 dual inhibitor development candidate with combination opportunities with multiple programs in the Company's pipeline. IND filing targeted for the second half of 2025."
IND • Oncology
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