immunoglobulin therapy / Wuhan Union Hospital - LARVOL DELTA

The Status of Pediatric Patients With Hematological Malignancy During COVID-19 Pandemic in Wuhan City, China. (PubMed, J Pediatr Hematol Oncol) - "All the patients had routine blood and biochemical examination, as well as chest computed tomography scans, and the nucleic acid, immunoglobulin G-immunoglobulin M combined antibodies tests for SARS-CoV-2...Therefore, the incidence of SARS-CoV-2 infection in hematological malignancy children was low during the COVID-19 pandemic in China. COVID-19 got early detected and the virus spread out in the ward was effectively blocked by increasing test frequency and using single-room isolation for 5 to 7 days after admission."

Clinical • Journal • Hematological Disorders • Hematological Malignancies • Infectious Disease • Leukemia • Novel Coronavirus Disease • Oncology • Pediatrics • Respiratory Diseases • CRP

Risk factors of mortality and contribution of treatment in patients infected with COVID-19: a retrospective propensity score matched study. (PubMed, Curr Med Res Opin) - "Treatments with glucocorticoids, immunoglobulin, thymosin, and ammonium glycyrrhizinate were significantly associated with a higher rate of COVID-19 death...The results of this study do not support immunomodulatory therapy in patients admitted to hospital with COVID-19. Further prospective studies are essential to clarify our findings, especially for non-critically ill patients."

Journal • Retrospective data • Immune Modulation • Infectious Disease • Inflammation • Novel Coronavirus Disease • Respiratory Diseases

Diarrhea is associated with prolonged symptoms and viral carriage in COVID-19. (PubMed, Clin Gastroenterol Hepatol) - "At a single center in Wuhan, China, 31% of patients with SARS-CoV-2 pneumonia had diarrhea. A significantly higher proportion of patients with diarrhea have virus RNA in stool than patients without diarrhea. Elimination of SARS-CoV-2 from stool takes longer than elimination from the nose and throat."

Journal • Infectious Disease • Novel Coronavirus Disease • Pneumonia • Respiratory Diseases

A cluster of health care workers with COVID-19 pneumonia caused by SARS-CoV-2. (PubMed, J Microbiol Immunol Infect) - "Human-to-human transmission of COVID-19 pneumonia has occurred among HCWs, and most of these infected HCWs with confirmed COVID-19 are mild cases. Our data suggest that in the epidemic area of COVID-19, stringent and urgent surveillance and infection-control measures should be implemented to protect doctors and nurses from COVID-19 infection."

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