HP161 / Stainwei Biotech - LARVOL DELTA

Assessing the potential impacts of California Senate Bill 27 (SB27) on the antimicrobial susceptibility of Escherichia coli from raw meat. (PubMed, Environ Health Perspect) - "The lack of publicly available data regarding actual antimicrobial use in California and non-California broiler chicken production limits our ability to make stronger conclusions about our observations. https://doi.org/10.1289/EHP16115."

Journal

Exposure to organophosphate ester flame retardants and plasticizers during pregnancy and autism-related outcomes in the ECHO Cohort. (PubMed, Environ Health Perspect) - "Prenatal exposure to OPEs, specifically BCPP and BBOEP, may be associated with higher risk of autism diagnosis and related traits in childhood. https://doi.org/10.1289/EHP16177."

Journal • Autism Spectrum Disorder • Genetic Disorders

Expanded Tox21 biological assay panel for the prediction of drug-induced liver injury and cardiotoxicity. (PubMed, Environ Health Perspect) - "This improvement underscores the importance of a diverse and comprehensive in vitro assay portfolio in advancing safety assessment. https://doi.org/10.1289/EHP16190."

Journal • Cardiovascular • Hepatology • Liver Failure

Construction of novel multi-epitope-based diagnostic biomarker HP16118P and its application in the differential diagnosis of Mycobacterium tuberculosis latent infection. (PubMed, Mol Biomed) - "It was found that the Quadratic discriminant analysis model exhibited the best diagnostic performance for discriminating between LTBI and ATB, with a sensitivity of 1.00, specificity of 0.86, and accuracy of 0.93. In summary, HP16118P has demonstrated strong antigenicity and immunogenicity, with the induction of GM-CSF, IL-23, IL-5, and MCP-3, suggesting their potential for the differential diagnosis of LTBI and ATB."

Biomarker • Journal • Infectious Disease • Pulmonary Disease • Respiratory Diseases • Tuberculosis • CSF2 • IFNG • IL23A • IL5

Relationship between Climate Variables and Dengue Incidence in Argentina. (PubMed, Environ Health Perspect) - "The higher incidence of dengue virus and its expansion to different regions of Argentina seem to be associated with temperature increases in the country during the past two decades. The active surveillance of both the vector and associated arboviruses, together with continued meteorological data collection, will facilitate the assessment and prediction of future epidemics that use trends in the accelerated changes in climate. Such surveillance should go hand in hand with efforts to improve the understanding of the mechanisms driving the geographic expansion of dengue and other arboviruses beyond the current limits. https://doi.org/10.1289/EHP11616."

Journal • Dengue Fever

Residential Greenness and Cardiovascular Disease Incidence, Readmission, and Mortality. (PubMed, Environ Health Perspect) - "Living in urban areas with more green spaces was associated with improved cardiovascular health in people free of AMI and HF but not among individuals who have already developed these conditions. https://doi.org/10.1289/EHP6161."

Journal • Cardiovascular • Congestive Heart Failure • Heart Failure • Myocardial Infarction

Environmental Health Practice Challenges and Research Needs for U.S. Health Departments. (PubMed, Environ Health Perspect) - "EH professionals are strategically positioned to diagnose, intervene, and prevent public health threats. Focus group engagement resulted in 29 priority problem statements partitioned among 6 EH topic areas: a) drinking water quality, b) wastewater management, c) healthy homes, d) food safety, e) vectors and public health pests, and f) emerging issues. This commentary article identifies priority challenges and related research needs to catalyze effective delivery of essential environmental public health services for common EH program areas in health departments. An unprecedented initiative to revitalize EH practice with timely and strategic recommendations for student and professional training, nontraditional partnerships, and basic and translational research activities is recommended. https://doi.org/10.1289/EHP5161."

Journal

"Surveillance for Cervical Precancer in the Era of the HPV Vaccine: From 2008 through 2014 the proportion of CIN2 attributable to HPV1618 declined. https://t.co/ftCZ8V0Lzo" (@womens_womens)