AMG 378 / Amgen - LARVOL DELTA

Single and Multiple Ascending Dose Study of AMG 378 in Healthy Participants (clinicaltrials.gov) - P1 | N=48 | Terminated | Sponsor: Amgen | Recruiting ➔ Terminated | Trial primary completion date: Sep 2026 ➔ Jan 2026 | N=92 ➔ 48 | Trial completion date: Oct 2026 ➔ Jan 2026; Business Decision

Enrollment change • Trial completion date • Trial primary completion date • Trial termination

Single and Multiple Ascending Dose Study of AMG 378 in Healthy Participants (clinicaltrials.gov) - P1 | N=92 | Recruiting | Sponsor: Amgen | Trial completion date: Oct 2028 ➔ Oct 2026 | Trial primary completion date: Oct 2028 ➔ Sep 2026

Trial completion date • Trial primary completion date