PCV24 / Merck (MSD) - LARVOL DELTA

Immunogenicity of PCV24, an expanded pneumococcal conjugate vaccine, in adult monkeys and protection in mice. (PubMed, Vaccine) - "Of the serotypes common to PCV13 and V114 (PCV15), PCV24 had a similar immunogenic response with the exceptions of 23F which had higher IgG GMCs for PCV13 and V114, and 7F which had higher GMCs for PCV13. Overall, this study shows that PCV24 provided similar immunogenicity as the lower valent vaccines in adult monkeys with no apparent serotype interference. In addition, PCV24 also provided protection against pneumococcal infection in a mouse challenge model."

Journal • Preclinical • CNS Disorders • Infectious Disease • Pneumococcal Infections • Pneumonia • Respiratory Diseases • Septic Shock