Large Surface Area Microparticle Cisplatin (LSAM-Cisplatin) / NanOlogy - LARVOL DELTA

TIGER-1: Targeted LSAM-Cisplatin Infusion in Gliomas, Evaluation of Response (clinicaltrials.gov) - P1/2 | N=20 | Not yet recruiting | Sponsor: NanOlogy, LLC

New P1/2 trial • Brain Cancer • Diffuse Intrinsic Pontine Glioma • Diffuse Midline Glioma • Glioma • Oncology • Solid Tumor

NanOlogy Unveils Drug Development Program for Rare Pediatric Brainstem Tumor (PRNewswire) - "Upon completion of these studies, the company plans to submit an IND application for LSAM-Cisplatin to treat malignant neoplasms of the brain including DIPG. Subject to FDA allowance to proceed, NanOlogy aims to initiate a clinical trial in late 2026 to evaluate the safety and response of stereotactic IT administration of LSAM-Cisplatin in children diagnosed with DIPG."

IND • New trial • Diffuse Intrinsic Pontine Glioma