fluoxymesterone / Generic mfg. - LARVOL DELTA

Comprehensive metabolic profiling of fluoxymesterone in vivo by GC-Orbitrap HRMS: a integrated strategy for novel biomarkers discovery in doping analysis. (PubMed, Anal Bioanal Chem) - "Notably, the newly identified metabolite F-M7 (9α-fluoro-17α-methyl-3ξ,11β,17β-triol-5ξ-androstane) was detectable as a glucuronide conjugate for up to 5 days post-administration, highlighting its potential as a reliable biomarker. These findings expand the understanding of fluoxymesterone metabolism in vivo and propose promising analytical targets for enhancing the sensitivity and reliability of anti-doping strategies."

Journal • Preclinical

A novel non-biological dual identification system based on SBE-β-CD@CdTe for the simultaneous detection of multiple steroids in environmental water. (PubMed, Anal Chim Acta) - "The sensor was then applied to simultaneously monitor dexamethasone, fluoxymesterone, and chlormadinon in environmental water samples, and the results were satisfactory with detection limits of 4.1 nmol L-1, 3.4 nmol L-1, and 7.7 nmol L-1, respectively. Thus, this sensing system enables the rapidly identifying multiple SHs in the aquatic environment and has great potential applications in environmental studies, illicit addition and drug analysis. In addition, this study provides a new idea and theoretical basis for the construction of on-line monitoring method for strong physiologically active components."

Journal

Evaluation of the androgen receptor in patients with ERα-positive early breast cancer treated with adjuvant tamoxifen ± fluoxymesterone. (PubMed, Breast Cancer Res) - "Our findings suggest that an AR-agonist may be of value in AR-enriched, ER-enriched breast cancers and should be studied in future trials because of the availability of new, more tolerable AR-agonists."

Clinical • Journal • Breast Cancer • Estrogen Receptor Positive Breast Cancer • Hormone Receptor Breast Cancer • Hormone Receptor Positive Breast Cancer • Oncology • Solid Tumor • AR • ER

50 Years Ago in The Journal of Pediatrics: Growth in Patients with Gonadal Dysgenesis Receiving Fluoxymesterone. (PubMed, J Pediatr) - No abstract available

Clinical • Journal • Pediatrics