mesenchymal stem cell therapy / Xinxiang Medical University - LARVOL DELTA

The critical role of Id2 gene in mesenchymal stem cell therapy for colitis through regulating immune response and microbiota. (PubMed, Int Immunopharmacol) - "Transcriptome sequencing analysis revealed altered gene expression involved in immune regulation and signaling pathways (Wnt and Notch), including downregulation of CD1D, CD83, SAMHD1, PRRX1, AXIN2, JAG1, and DLL1, alongside upregulation of SPHK1. Our findings underscore the pivotal role of Id2 in the therapeutic efficacy of MSC treatments for UC."

Journal • Gastroenterology • Gastrointestinal Disorder • Immunology • Inflammatory Bowel Disease • Ulcerative Colitis • CD83 • ID2 • JAG1 • PRRX1 • SPHK1