BM-011 / BIMINI Biotech - LARVOL DELTA

WASP activation by BM011 triggers mitochondrial collapse and aldolase-dependent glycolytic vulnerability in lymphoma (AACR 2026) - "BM011-driven activation of WASP induces cytoskeletal stress, mitochondrial import failure, and a proteotoxic response, with upper-glycolysis and aldolase acting as a metabolic safety valve. These reveal druggable metabolic-cytoskeletal vulnerabilities in lymphoma."

Hematological Malignancies • Lymphoma • Mantle Cell Lymphoma • Oncology • ENO1 • PFKFB3 • PFKFB4 • PFKL • PFKM • PGK1