RK-582 / Riken - LARVOL DELTA

LUMEN: A Lightweight UAV Multi-Enhanced Network for PSD-Based RF Fingerprinting on Edge Devices. (PubMed, Sensors (Basel)) - "The proposed pipeline covers UAV RF data collection, including UAV RF data collection, dataset construction, preprocessing, model design, comparative evaluation, and deployment on an RK3582-based edge platform...In the edge deployment test, the model maintained an average inference latency of 1.73 ms and a throughput of 578.95 FPS during a 30-min continuous run, while showing low CPU utilization, low memory usage, and stable thermal behavior. These results demonstrate that LUMEN achieves a practical balance between identification accuracy and runtime efficiency for real-time UAV identification on edge devices."

Journal

RK-582, a tankyrase inhibitor, attacks Wnt-driven colorectal cancer cells with short-type APC mutations and high β-catenin expression (AACR 2026) - "In summary, RK-582 targets the Wnt/β-catenin pathway, a key cancer pathway previously considered undruggable. An investigator-initiated first-in-human clinical trial of this drug is currently ongoing, and these findings are expected to contribute to the development of an innovative therapy for unresectable advanced and recurrent CRC."

First-in-human • IO biomarker • Colorectal Cancer • Oncology • Solid Tumor • APC • AXIN1 • BRAF • CTNNB1 • KRAS • PIK3CA