azathioprine
/ Generic mfg.
- LARVOL DELTA
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March 26, 2026
Evaluation of TNF-alpha antagonists (infliximab) withdrawal in sarcoidosis
(clinicaltrialsregister.eu)
- P2/3 | N=90 | Active, not recruiting | Sponsor: Assistance Publique Hopitaux De Paris | Recruiting ➔ Active, not recruiting
Enrollment closed • Immunology • Sarcoidosis
March 20, 2026
CUTANEOUS MANIFESTATIONS IN RENAL TRANSPLANT RECIPENTS: A SINGLE CENTER, CROSS-SECTIONAL STUDY IN THAILAND
(ISN-WCN 2026)
- "Immunosuppressive regimens included calcineurin inhibitors, azathioprine, mycophenolate mofetil/mycophenolic acid, cyclosporine, and prednisolone. Prednisolone dosages ≥ 20 mg/day correlated with significantly higher prevalence of herpes zoster (30% vs. 8%, p < 0.05), dermatophytes (20% vs. 4.8%, p < 0.05), pityrosporum folliculitis (50% vs. 5.6%, p < 0.001), and acneiform eruptions (50% vs. 5.6%, p < 0.001).Conclusion Skin conditions are prevalent in RTRs, particularly after the first-year post-transplant. Associations between graft rejection, high-dose prednisolone, and herpes zoster warrant further study."
Clinical • Observational data • Herpes Simplex • Herpes Zoster • Infectious Disease • Transplant Rejection • Transplantation • Varicella Zoster
March 20, 2026
EVALUATION OF RENAL OUTCOMES IN IGA NEPHROPATHY PATIENTS IN THE NATIONAL KIDNEY AND TRANSPLANT INSTITUTE RECEIVING SGLT2 INHIBITOR TREATMENT VERSUS STANDARD OF CARE — A RETROSPECTIVE STUDY
(ISN-WCN 2026)
- "The standard treatment protocol for individuals with IgA nephropathy includes using supportive measures such as lifestyle intervention, medications inhibiting renin-angiotensin-aldosterone system (RAAS), fish oil, with or without any immunosuppressive agents like steroids, azathioprine, mycophenolate mofetil, cyclophosphamide, or rituximab. Standard treatment led to higher progression to renal replacement therapy. SGLT2 inhibitors combined with standard therapy and supportive care, provide enhanced kidney protection in IgA nephropathy."
Retrospective data • Glomerulonephritis • IgA Nephropathy • Inflammation • Lupus Nephritis • Renal Disease • Transplantation
March 20, 2026
FOUR DECADES OF SUCCESS: A CASE SERIES OF KIDNEY ALLOGRAFT SURVIVAL EXCEEDING 40 YEARS UNDER HISTORICAL IMMUNOSUPPRESSION REGIME
(ISN-WCN 2026)
- "The key factor associated with this unprecedented longevity appears to be the complete absence of documented rejection episodes in all patients. This series highlights that, in a carefully selected patient cohort with high adherence and low immunological risk, the historical combination of Azathioprine and Prednisone can achieve extraordinary long-term outcomes, despite the recipient's advanced age and the absence of modern maintenance drugs."
Clinical • Diabetes • Diabetic Nephropathy • Hypertension • Metabolic Disorders • Nephrology • Oral Cancer • Tongue Carcinoma • Transplant Rejection
March 20, 2026
COMPARATIVE ANALYSIS BETWEEN PEDIATRIC AND ADULT KIDNEY TRANSPLANT RECIPIENTS: A MULTICENTRIC RETROSPECTIVE STUDY
(ISN-WCN 2026)
- "As for maintenance therapy, all pediatric patients received steroids, and they were more frequently treated with azathioprine (12.5% vs 0.3%, p < 0.001) and cyclosporine (6.7% vs 0.6%, p < 0.001), whereas mTOR inhibitors were used exclusively in adults (25.2% vs 0%, p < 0.001). Mycophenolate mofetil was slightly more common in pediatric patients (86.5% vs 76.2%, p = 0.025)...Despite distinct immunological and clinical differences, graft survival, rejection rates, and disease recurrence were comparable between groups. Based on our results, future clinical trials should include pediatric cohorts to ensure equitable treatment across all age groups."
Retrospective data • Infectious Disease • Nephrology • Pediatrics • Transplantation
March 20, 2026
PHASE 1 STUDY EVALUATING HYDROGEL-FORMULATED UC-MSCS ADMINISTERED SUBCUTANEOUSLY IN ADDITION TO STANDARD OF CARE AS A TREATMENT FOR LUPUS NEPHRITIS
(ISN-WCN 2026)
- P1 | "Lupus treatment relies on the use of glucocorticoids and conventional immunosuppressants (e.g. methotrexate, azathioprine, or mycophenolate mofetil) and targeted therapies (e.g. belimumab, anifrolumab, or voclosporin) to control disease activity and prevent relapse...Secondary endpoints include changes from baseline in SLE activity scores, patient-reported QoL measurements and prednisone administrationResults As of Oct...Investigation of the safety and clinical utility of SC-administered hf-UC-MSCs as a treatment for lupus and LN is ongoing. Further conclusions to be based on data collected through Jan., 2026"
Late-breaking abstract • P1 data • Glomerulonephritis • Immunology • Inflammatory Arthritis • Lupus • Lupus Nephritis • Nephrology
March 20, 2026
EVALUATION OF LONG-TERM RENAL FUNCTION IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE: COMPARISON BETWEEN ULCERATIVE COLITIS AND CROHN'S DISEASE
(ISN-WCN 2026)
- "In contrast, the use of 5-aminosalicylic acid and azathioprine tended to attenuate the decline in eGFR.Conclusion Patients with UC experienced a significantly faster decline in renal function than patients with CD. Furthermore, since nutritional status and medications have long been associated with renal function in IBD patients, appropriate disease control, optimization of nutritional status, and careful management of comorbidities such as hypertension may play an important role in preserving renal function and improving long-term renal outcomes."
Clinical • Acute Kidney Injury • Cardiovascular • Crohn's disease • Gastroenterology • Gastrointestinal Disorder • Hypertension • Immunology • Inflammation • Inflammatory Bowel Disease • Nephrology • Renal Disease • Ulcerative Colitis
March 20, 2026
C1Q-POSITIVE DE NOVO IGA NEPHROPATHY FOLLOWING COVID-19 INFECTION, CONFIRMED BY GD-IGA1 STAINING AFTER KIDNEY TRANSPLANTATION
(ISN-WCN 2026)
- "She was maintained on steroids, tacrolimus, azathioprine and everolimus, and serum creatinine remained stable at 1.0-1.2 mg/dL. She contracted COVID-19 and was treated with molnupiravir three months before this visit...Consequently, treatment with enalapril and dapagliflozin was initiated, and steroid dosage was tapered.Results The patient exhibited no risk factors for secondary IgAN, and the diagnosis of IgAN was confirmed through Gd-IgA1 staining...Furthermore, the presence of C1q deposits, which are uncommon and considered indicators of poor renal prognosis in primary IgAN, was noted in this patient. Based on the clinical progression, C1q deposits in de novo IgAN may similarly be associated with adverse renal outcomes.This work was first presented at ASN Kidney Week 2025, and re-submission is permitted by ASN.Conclusion"
ANCA Vasculitis • Fibrosis • Glomerulonephritis • IgA Nephropathy • Immunology • Infectious Disease • Novel Coronavirus Disease • Renal Disease • Respiratory Diseases • Transplantation • Vasculitis
March 20, 2026
ISOLATED URINARY TRACT INVOLVEMENT IN IGG4-RELATED RETROPERITONEAL FIBROSIS: DIAGNOSTIC DELAY LEADING TO IRREVERSIBLE UNILATERAL RENAL ATROPHY
(ISN-WCN 2026)
- "Immunosuppressive therapy with prednisolone (10 mg/day) and mycophenolate mofetil (360 mg/day) produced partial improvement...Recurrent urinary infections with Pseudomonas aeruginosa were managed with antibiotics.A literature review of 60 reported IgG4-related RPF cases showed that corticosteroid therapy was used in 75% (45/60) of patients, while immunomodulatory agents (rituximab, mycophenolate, azathioprine) were less common...IgG4-RD should be considered in patients with RPF or unexplained ureteral obstruction to enable early diagnosis, decompression, and timely immunosuppression. Therefore, prompt recognition is crucial to prevent irreversible renal injury and preserve function."
Chronic Kidney Disease • Fibrosis • Immunology • Infectious Disease • Inflammation • Nephrology • Renal Disease • Urology
March 20, 2026
A CASE OF A MAINTENANCE DIALYSIS PATIENT WITH COMBINED PULMONARY-LIMITED AL AMYLOIDOSIS AND MALT LYMPHOMA REVEALED AT AUTOPSY
(ISN-WCN 2026)
- "She was treated with prednisolone, mizoribine, and azathioprine but developed end-stage renal disease requiring hemodialysis ten years later.Seven years before death, she exhibited elevated immunoglobulins and an IgA-κ M-protein, diagnosed as monoclonal gammopathy of undetermined significance (MGUS)...Melphalan and dexamethasone therapy were initiated for localized pulmonary amyloidosis, but respiratory failure gradually progressed, requiring home oxygen therapy.She later suffered a fatal intracerebral hemorrhage unrelated to coagulation disorders or hypoglycemia...MALT lymphoma occurs in approximately 4–8% of SS-related lymphomas and most frequently arises in the stomach, though endoscopic findings can be subtle and nonspecific.In this patient, MALT lymphoma was diagnosed only postmortem, indicating that earlier endoscopic surveillance might have enabled detection and management. The case highlights the need for continuous vigilance for lymphoproliferative complications..."
Clinical • Amyloidosis • Cerebral Hemorrhage • Conjunctivitis • Dental Disorders • Dry Eye Disease • Extranodal Marginal Zone Lymphoma • Hematological Malignancies • Hypoglycemia • Immunology • Indolent Lymphoma • Infectious Disease • Interstitial Lung Disease • Lymphoma • Marginal Zone Lymphoma • Monoclonal Gammopathy • Nephrology • Ocular Infections • Ocular Inflammation • Ophthalmology • Pneumonia • Pulmonary Disease • Renal Disease • Respiratory Diseases • Sjogren's Syndrome • Xerostomia
March 20, 2026
IMPACT OF DONOR APOL1 VARIANTS ON LONG-TERM GRAFT SURVIVAL IN BRAZILIAN LIVING KIDNEY TRANSPLANTATION: INTERIM ANALYSIS OF THE BRIDGES-APOL1 STUDY
(ISN-WCN 2026)
- "Induction therapy with thymoglobulin or basiliximab was used in 31.9% of recipients. Maintenance immunosuppression predominantly included a calcineurin inhibitor combined with azathioprine (69.8%), with no significant differences between groups...The prevalence of risk variants was consistent with previous studies involving relatives of dialysis patients. The presence of at least one APOL1 risk variant independently increased the long-term risk of graft loss by 63%, highlighting the potential clinical relevance of donor genetic screening in kidney transplantation."
Transplantation
March 20, 2026
UNFOLDING THE MYSTERY OF THROMBOTIC MICRO-ANGIOPATHY IN KIDNEY TRANSPLANTATION: ITS INCIDENCE, RISK FACTORS AND CLINICAL OUTCOMES THROUGH BIOPSY PRECISION
(ISN-WCN 2026)
- "At the time of diagnosis of TMA 58 patients (46%) had Deltacortil+ Azathioprine+ cyclosporine as immunosuppression of choice. Mean Serum Creatinine at the time of diagnosis of TMA is 1.94±0.93, while serum creatinine at 3 months post TMA found to be 2.21±1.67 and at 6 months 2.16±1.62 and after 1 year was 2.37±1.95. 55 patients (43.7%) had complete recovery, 38 (30.2%) showed no response, 15 (11.9%) developed ESRD with mortality in 6 (4.8%) as an outcome 1 year post transplantation.Conclusion Thrombotic Micro-angiopathy occurring after transplant adversely affects graft function and a significant minority lose their graft in one year."
Biopsy • Clinical • Clinical data • Antibody-mediated Rejection • Chronic Kidney Disease • Infectious Disease • Transplantation • KEAP1
March 20, 2026
A WOMAN 38-YEAR-OLD LUPUS NEPHRITIS WITH RO-60 AND SCL-70 POSITIVE DURING PREGNANCY
(ISN-WCN 2026)
- "The patient received therapy with aspirin 80 mg once a day, folic acid 400 mcg twice a day, ferrous sulfate twice a day, calc once a day, nifedipine 10 mg 3 times a day, azathioprine 50 mg twice a day, hydroxychloroquine 200 mg once a day, methylprednisolone 16 mg twice a day.Results Pregnant women with LN are at increased risk for complications like pre-eclampsia, intrauterine growth restriction, stillbirth, and preterm delivery. During pregnancy, LN patients are managed by a multidisciplinary team (rheumatology, gynecology, obstetrics, and neonatology). Routine assessment involving close clinical and laboratory monitoring every 4-6 weeks to detect early signs of disease activity."
Clinical • Amyloidosis • ANCA Vasculitis • Cardiovascular • Glomerulonephritis • Gynecology • Hypertension • Immunology • Inflammatory Arthritis • Lupus • Lupus Nephritis • Monoclonal Gammopathy • Nephrology • Obstetrics • Vasculitis
March 20, 2026
LEYDIG CELL HYPERPLASIA PRESENTING AS PRIMARY AMENORRHEA IN A KIDNEY TRANSPLANT PATIENT WITH FRASIER SYNDROME
(ISN-WCN 2026)
- "Post-transplant, she was maintained on cyclosporine and azathioprine until acute T-cell-mediated rejection in 2023 prompted rituximab and switch to tacrolimus, mycophenolate, and prednisone. Early genetic and pathologic evaluation in transplant recipients presenting with primary amenorrhea is essential to guide prophylactic gonadectomy, optimize hormone replacement, and prevent gonadal malignancy while preserving graft function. Multidisciplinary management—including nephrology, endocrinology, genetics, and psychosocial support—remains critical for long-term outcomes in this rare but clinically significant entity."
Clinical • Cognitive Disorders • Endocrine Disorders • Glomerulonephritis • Lupus Nephritis • Nephrology • Ovarian Cancer • Rare Diseases • Solid Tumor • Transplantation • Turners Syndrome • Wilms Tumor • Women's Health • WT1
March 20, 2026
DE NOVO IDIOPATHIC NODULAR GLOMERULOSCLEROSIS IN A KIDNEY TRANSPLANT PATIENT
(ISN-WCN 2026)
- "Early on, he began to present elevation of azotes without an apparent cause, for which a first renal biopsy was performed with an official report given by BANFF category 3: suspected (borderline) of cell rejection, in the same way a change of therapeutic scheme was carried out suspending mycophenolate and initiation of azathioprine, other infectious etiologies causing graft dysfunction were ruled out...To optimize antiproteinuric therapeutic management, ARA II was changed from losartan to irbesartan and iSGLT2 was initiated...Timely detection and appropriate management can contribute to improving the prognosis and quality of life of affected patients. More multicenter studies and case reports are needed to better understand the course, prognosis, and best therapeutic strategies for this rare entity."
Clinical • Amyloidosis • Cardiovascular • Chronic Kidney Disease • Cystic Fibrosis • Diabetic Nephropathy • Fibrosis • Focal Segmental Glomerulosclerosis • Genetic Disorders • Glomerulonephritis • Hypertension • IgA Nephropathy • Immunology • Infectious Disease • Lupus Nephritis • Metabolic Disorders • Obesity • Respiratory Diseases • Transplant Rejection • Transplantation
March 20, 2026
SYSTEMIC LUPUS ERYTHEMATOSUS AND ITS COMPLICATIONS: AN UNDERDIAGNOSED DISEASE IN CHAD
(ISN-WCN 2026)
- "All patients were on hydroxychloroquine and corticosteroid therapy. Induction treatment in lupus nephropathy consisted of the administration of azathioprine in 38.5% (n=5)...Its clinical expression is polymorphic and dominated by arthrocutaneous involvement. Renal complications are fatal for patients."
Cardiovascular • Immunology • Inflammatory Arthritis • Lupus • Musculoskeletal Pain • Pulmonary Arterial Hypertension • Pulmonary Embolism • Renal Disease • Respiratory Diseases • Septic Shock • Systemic Lupus Erythematosus
March 20, 2026
CLINICAL IMPACT OF IMMUNOSUPPRESSIVE COMBINATION THERAPY IN MPO-ANCA–ASSOCIATED RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS: A RETROSPECTIVE COMPARISON WITH STEROID MONOTHERAPY
(ISN-WCN 2026)
- "This study aimed to compare the clinical course, renal outcomes, and safety between the two treatment strategies in MPO-ANCA–associated RPGN.Methods We retrospectively analyzed patients diagnosed with AAV-related RPGN at our hospital between April 2012 and March 2025.Inclusion criteria:(1) Age ≥18 years; (2) positive for myeloperoxidase (MPO)-ANCA; (3) diagnosis of microscopic polyangiitis (MPA); and(4) ≥6 months of follow-up after initiation of therapy.Exclusion criteria:(1) proteinase-3 (PR3)-ANCA positivity,(2) anti-glomerular basement membrane (GBM) antibody positivity,(3) drug-induced vasculitis, and(4) patients who required maintenance dialysis from the time of diagnosis.A total of 70 patients were included: 44 in the steroid monotherapy group and 26 in the immunosuppressive combination group.Immunosuppressive agents included rituximab (RTX), azathioprine (AZA), and avacopan, and treatment choice was at the discretion of the attending physician.Clinical..."
Combination therapy • Monotherapy • Retrospective data • ANCA Vasculitis • Diabetes • Diabetic Nephropathy • Glomerulonephritis • Infectious Disease • Lupus Nephritis • Metabolic Disorders • Nephrology • Vasculitis • MPO
March 20, 2026
LATE RELAPSE OF ANCA ASSOCIATED VASCULITIS PRESENTING AS OBSTRUCTIVE NEPHROPATHY DUE TO RETROPERITONEAL FIBROSIS
(ISN-WCN 2026)
- "He had been treated with steroids, cyclophosphamide and plasmapheresis. He had achieved complete remission, and thereafter received maintenance immunosuppression with steroids and azathioprine for almost seven years...He was also administered Inj Rituximab 1g, repeated 6 monthly. 30 months later his renal functions are normal and PR-3 antibodies undetectable.Results Download: Download high-res image (358KB)Download: Download full-size imageDownload: Download high-res image (359KB)Download: Download full-size imageConclusion Low backache is a common problem in the population. In a known case of AAV it is important to have a high index of suspicion of retro-peritoneal fibrosis so that the diagnosis is not missed / delayed."
ANCA Vasculitis • Back Pain • Fibrosis • Glomerulonephritis • Hematological Malignancies • Hepatology • Immunology • Lupus Nephritis • Lymphoma • Musculoskeletal Diseases • Nephrology • Orthopedics • Renal Disease • Vasculitis
March 20, 2026
EXPERIENCE WITH AVACOPAN FOR THE TREATMENT OF ANTI-NEUTROPHIL CYTOPLASMIC ANTIBODY (ANCA)-ASSOCIATED VASCULITIS (AAV) IN THE NEPHROLOGY DEPARTMENT OF NISHI-KOBE MEDICAL CENTER.
(ISN-WCN 2026)
- "Concomitant immunosuppressive agents included cyclophosphamide in 6 patients, rituximab in 2, azathioprine in 5, and mizoribine in 6; 2 patients underwent plasma exchange.Clinical remission was achieved in 85% of patients at 26 weeks...Avacopan was restarted at a lower dose in all cases—one with concomitant ursodeoxycholic acid and another after alcohol abstinence. No infections requiring hospitalization were observed during the observation periodConclusion Avacopan appeared to be a safe and effective glucocorticoid-sparing therapeutic option for AAV. However, regular monitoring of liver function is warranted.I have potential conflict of interest to disclose.I have received lecture fees from KISSEI PHARMACEUTICAL CO.,LTD.I did not use generative AI and AI-assisted technologies in the writing process."
ANCA Vasculitis • Atherosclerosis • Cardiovascular • Infectious Disease • Nephrology • Rare Diseases • Vasculitis
March 20, 2026
EFFICACY AND SAFETY OF TELITACICEPT IN TREATMENT OF MINIMAL CHANGE DISEASE AND GENERALIZED MYASTHENIA GRAVIS
(ISN-WCN 2026)
- "It simultaneously blocks two key B-cell activating factors: BAFF (B-cell activating factor) and APRIL (A proliferation-inducing ligand).Methods A 68-year-old male with stage III generalized and treated with methylprednisolone and azathioprine 50 mg bid for 4 years. No severe infections or adverse events were observed.Download: Download high-res image (140KB)Download: Download full-size imageDownload: Download high-res image (132KB)Download: Download full-size imageDownload: Download high-res image (156KB)Download: Download full-size imageConclusion This case highlights the therapeutic potential of telitacicept in overlapping autoimmune conditions. By targeting BAFF and APRIL pathways, telitacicept may provide dual benefits in controlling renal autoimmunity and antibody-mediated neuromuscular dysfunction."
Clinical • CNS Disorders • Glomerulonephritis • Immunology • Infectious Disease • Myasthenia Gravis
March 20, 2026
NUDGING NEPHROLOGISTS IN CARDIOVASCULAR RISK ASSESSMENT AND MANAGEMENT IN LUPUS NEPHRITIS
(ISN-WCN 2026)
- "Prednisolone was prescribed at 89.5% of the visits at the median dose of 5 (1-70) mg per day, while mycophenolate mofetil or sodium, calcineurin inhibitor, azathioprine and cyclophosphamide were prescribed at 77.8%, 40.5%, 2.6% and 2.6% of the visits, respectively.Glycemic evaluation occurred at 43.9% and 64.8% of the pre- and post-intervention visits, respectively. Lipid evaluation occurred at 36.6% and 33.8% of the pre- and post-intervention visits, respectively. Glycemic evaluation was increased during post-intervention visits compared to pre-intervention visits [odds ratio (OR) 2.99 (95% CI: 1.29, 6.89), p=0.01] but lipid evaluation was unchanged [OR 0.72 (95% CI: 0.30, 1.74), p=0.46.Conclusion A physician-directed nudge significantly increased glycemic evaluation but not lipid evaluation in older patients with LN treated with immunosuppressants."
Cardiovascular • Glomerulonephritis • Immunology • Inflammatory Arthritis • Lupus • Lupus Nephritis • Metabolic Disorders • Nephrology
March 20, 2026
RECURRENT HYPOKALEMIA: THE HIDDEN FOOTPRINT OF AN AUTOIMMUNE DISTAL RENAL TUBULAR ACIDOSIS. CASE REPORT
(ISN-WCN 2026)
- "The patient received potassium and bicarbonate replacement followed by methylprednisolone pulses and maintenance therapy with azathioprine, hydroxychloroquine, and prednisone, achieving full recovery of muscle strength and stable serum potassium levels upon follow-up.Conclusion his case highlights the importance of pathophysiological reasoning and comprehensive renal assessment in patients with recurrent hypokalemia. Autoimmune distal renal tubular acidosis should be suspected in young women presenting with unexplained episodes of muscle weakness and metabolic acidosis."
Case report • Clinical • Immunology • Inflammatory Arthritis • Lupus • Metabolic Disorders • Nephrology • Sjogren's Syndrome • Systemic Lupus Erythematosus
March 20, 2026
TRUE, TRUE, & RELATED: SECONDARY IGA NEPHROPATHY WITH SARCOIDOSIS
(ISN-WCN 2026)
- No abstract available
Acute Kidney Injury • Cardiovascular • Chronic Kidney Disease • Diabetes • Diabetic Nephropathy • Endocrine Disorders • Fibrosis • Focal Segmental Glomerulosclerosis • Gastrointestinal Disorder • Glomerulonephritis • Hepatology • Hypertension • IgA Nephropathy • Immunology • Infectious Disease • Lupus Nephritis • Metabolic Disorders • Myositis • Renal Calculi • Renal Disease • Sarcoidosis • Type 2 Diabetes Mellitus • IL2
March 25, 2026
Steroid-Resistant Immune Thrombocytopenia With Severe Bleeding Successfully Managed Using Eltrombopag and Mycophenolate in a 67-Year-Old Male.
(PubMed, Cureus)
- "Despite high-dose intravenous methylprednisolone followed by oral corticosteroids, platelet count remained 8 × 10³ per microliter...Azathioprine was discontinued, and mycophenolate mofetil was started. Platelet count rose steadily, reaching 88 × 10³ per microliter at discharge and normalizing to more than 150 × 10³ per microliter within two weeks, with complete resolution of bleeding. This case highlights the diagnostic challenges of ITP in older adults and supports combining thrombopoietin receptor agonists (TPO-RAs) with targeted immunosuppressive therapy in steroid-refractory disease."
Journal • Hematological Disorders • Immune Thrombocytopenic Purpura • Thrombocytopenia • Thrombocytopenic Purpura
March 25, 2026
Treatment Discontinuation in Patients With Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease.
(PubMed, JAMA Neurol)
- "A total of 83 patients (median [IQR] age, 42.7 [28.9-53.3] years; 52 [63.7%] female) discontinued either oral immunosuppressants (azathioprine or mycophenolate mofetil) or rituximab in 60 (72.1%) and 23 (27.7%) individuals, respectively. The low risk of disease reactivation found in this study suggests that discontinuing treatment may be considered in selected adult patients with MOGAD. Future clinical trials are necessary to confirm these results and establish guidelines in this situation."
Journal • CNS Disorders • Solid Tumor
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