amoxicillin / Generic mfg. - LARVOL DELTA

Prevalence, Antimicrobial Susceptibility, and Hygienic Practices of Escherichia coli O157:H7 in Raw Meat, Bahir Dar City, Ethiopia. (PubMed, Vet Med Sci) - "The detection of E. coli O157:H7 in nearly one-third of the samples and the occurrence of virulence genes in half of the isolates indicate the potential risk of foodborne infection in the study area. Therefore, food safety awareness and training for meat handlers should be encouraged to reduce the spread of this pathogen in Bahir Dar City."

Journal • Hematological Disorders • Infectious Disease

Urbanization impacts the environmental microbial community and its antibiotic phenotypic resistance potential by reshaping the diversity and network complexity. (PubMed, Environ Res) - "This phenotypic resistance potential, structured around nodes of cefalexin, amoxicillin, and fosfomycin, exhibited increased topological robustness, a doubling of inter-domain connectivity (bacterial-fungal), and an increase in positive correlation. To conclude, this study reveals that urbanization induces a trade-off between the overall cohesion of microbial ecosystems and the topological robustness of specialized AMR-networks. It highlights the interest of integrating high-resolution network analysis into One Health surveillance of AMR, to accurately predict and intercept the AMR spread in anthropized landscapes, even if this AMR-network constructed using culture-based methods have limitations."

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Drug-Induced Enterocolitis Syndrome in Children: A Report of Two Cases. (PubMed, Cureus) - "We present two pediatric cases of DIES triggered by amoxicillin...Laboratory findings, including leukocytosis, neutrophilia, and thrombocytosis, may support the diagnosis, but clinical recognition remains crucial, requiring high suspicion and increased awareness among clinicians. These cases highlight the diagnostic challenges in differentiating DIES from IgE-mediated drug hypersensitivity, the importance of conducting DPT in a controlled setting, and the need for further research on its pathophysiology, biomarkers, and prognosis."

Journal • Asthma • Conjunctivitis • Dermatology • Gastrointestinal Disorder • Hematological Disorders • Immunology • Ocular Infections • Ocular Inflammation • Ophthalmology • Pain • Pediatrics • Pulmonary Disease • Respiratory Diseases • Thrombocytosis • Urticaria

Trends and regional variation in antibiotic prescribing by dentists in Finland, 2012-2025: A register-based study. (PubMed, Eur J Oral Sci) - "Phenoxymethylpenicillin was the most frequently prescribed antibiotic, and its prescribing decreased by 28% in 2012-2019...Prescribing of amoxicillin increased by 41%, whereas prescribing of clindamycin decreased by 74% and that of doxycycline by 79%. There were up to 3- to 4-fold differences between counties in antibiotic prescription rates by dentists. Overall, there was a modest decline in the overall antibiotic prescribing rate by Finnish dentists, but regional variation in antibiotic prescribing was substantial."

Journal

A Diagnostic Challenge Involving Enterococcus faecalis Bacteremia: A Case Report. (PubMed, Cureus) - "Blood cultures at 48 hours grew Gram-positive cocci in pairs and chains and Enterococcus faecalis, prompting treatment with ceftriaxone and ampicillin and an extensive search for an infectious source...Repeat blood cultures cleared, and the patient was transitioned to oral amoxicillin on discharge with outpatient follow-up. This case highlights the importance of considering gastrointestinal sources, including colorectal neoplasia, in patients with E. faecalis bacteremia of unclear origin. It also supports the role of multidisciplinary evaluation, including infectious disease, cardiology, and gastroenterology, in guiding workup and management."

Journal • Atrial Fibrillation • Cardiovascular • Colonic Polyps • Colorectal Cancer • Endocrine Disorders • Gastroenterology • Hypertension • Infectious Disease • Mood Disorders • Musculoskeletal Pain • Oncology • Pain • Pneumonia • Psychiatry • Respiratory Diseases • Solid Tumor

Comparative Efficacy of Amoxicillin, Metronidazole, and Chlorhexidine in Preventing Alveolar Osteitis (clinicaltrials.gov) - P=N/A | N=240 | Not yet recruiting | Sponsor: Khyber Medical University Peshawar

New trial

Comment on "Efficacy and Safety of Tegoprazan-Amoxicillin Dual Therapy for Helicobacter pylori Eradication: A Systematic Review and Meta-Analysis With Trial Sequential Analysis of Randomized Controlled Trials". (PubMed, J Gastroenterol Hepatol) - No abstract available

Journal • Retrospective data • Infectious Disease

Species Diversity, Antimicrobial Susceptibility, and Provisional Epidemiological Cut-Off Values of Vibrio spp. Isolated From Pacific White Shrimp (Litopenaeus vannamei) Farms in Southern Thailand. (PubMed, J Fish Dis) - "Overall, the isolates were susceptible to oxytetracycline, doxycycline, ciprofloxacin, enrofloxacin, and florfenicol, with MIC50 ranging from ≤ 0.25 to 2 μg/mL...were resistant to amoxicillin, ceftriaxone, and sulfadimethoxine, with MIC50 values of at least 128 μg/mL...isolates, 83.10% were classified as wild type. Our findings highlight the need for strict regulation of antibiotic use in shrimp aquaculture to minimize the emergence and spread of antibiotic-resistant bacteria."

Journal

Amoxicillin and penicillin allergy direct oral challenge in a campus health clinic. (PubMed, J Am Coll Health) - " College health clinics are highly accessible, cost-effective, and regularly collect drug allergy information during routine care. With nearly a third of young adults in the U.S. attending higher education, the college health clinic is an ideal setting for amoxicillin DOC."

Journal • Allergy • Immunology

SPR-based screening identifies luteolin from Artemisia scoparia as a potential PBP2a inhibitor with β-lactam-potentiating activity against MRSA. (PubMed, Phytomedicine) - "Luteolin is a potential PBP2a-targeting compound with β-lactam-potentiating activity against MRSA. Its effects may involve PBP2a interaction and broader metabolic and regulatory perturbations, although direct inhibition of PBP2a enzymatic activity remains unconfirmed."

Journal • Infectious Disease

Occurrence and Antimicrobial Resistance Profiles of Escherichia coli along the Sheep Meat Production Chain: A One Health Approach. (PubMed, Int J Vet Sci Med) - "Antimicrobial susceptibility testing revealed that farm-derived E. coli isolates exhibited the highest resistance to amoxicillin (57.7%) but remained highly susceptible (≥ 95) to chloramphenicol and sulfamethoxazole/trimethoprim. In contrast, isolates from processing environments showed the highest resistance to tetracycline (60.5%) and highest susceptibility to chloramphenicol (76.3%)...The detection of multidrug-resistant E. coli across animal, human, and environmental interfaces highlights the interconnected nature of antimicrobial resistance and underscores the importance of the One Health approach in surveillance and control efforts. Strengthening hygiene and sanitation practices, together with promoting prudent antimicrobial use are essential to reducing the risk of foodborne infections and the dissemination of antimicrobial resistance within the sheep food production system."

Journal • Infectious Disease

Like father, like daughter: amoxicillin-induced aseptic meningitis in a female patient and her father: a case report. (PubMed, J Med Case Rep) - "Amoxicillin-induced aseptic meningitis is a rare adverse reaction that should be considered in patients presenting with severe headache in the absence of an identifiable pathogen. A thorough patient history combined with comprehensive diagnostic evaluation is essential to establish the diagnosis and to avoid unnecessary or excessive treatment. Additionally, potential genetic predispositions, as suggested in other forms of drug-induced aseptic meningitis, may play a role and should be considered in selected cases."

Journal • CNS Disorders • Infectious Disease • Otorhinolaryngology • Pain • Pulmonary Disease • Respiratory Diseases

Rethinking systemic adjuncts in periodontitis: a single centre acquisition cost comparison of antimicrobial and non-antimicrobial therapies. (PubMed, Br Dent J) - "Azithromycin accounted for 93.5% of periodontal prescriptions, whereas guideline-recommended amoxicillin plus metronidazole (A+M) represented 1.6%. Non-antimicrobial adjuncts demonstrated substantially greater reductions depending on treatment duration, with metformin 500 mg achieving up to 91.46% reduction.Conclusions Non-antimicrobial systemic adjuncts demonstrate considerable direct cost advantages over traditional antimicrobial regimens. These findings highlight potential economic and antimicrobial stewardship benefits and support the need for formal cost-effectiveness analyses to inform future prescribing guidance."

HEOR • Journal • Reimbursement • US reimbursement • Dental Disorders • Periodontitis

Comparative effectiveness of genotype-guided and empirical bismuth-containing quadruple therapy for Helicobacter pylori eradication: a retrospective study. (PubMed, Front Pharmacol) - "All regimens comprised bismuth potassium citrate 2.6 g, a proton pump inhibitor (PPI, esomeprazole 20 mg or ilaprazole 5 mg) or a potassium-competitive acid blocker (P-CAB, keverprazan 20 mg or tegoprazan 50 mg), and antibiotics selected from amoxicillin, clarithromycin, levofloxacin, furazolidone, tetracycline, metronidazole, or doxycycline. Dual clarithromycin and levofloxacin resistance and alcohol consumption remained key determinants of treatment failure even with genotype-guided therapy. However, the precision of estimates for single-drug resistance subgroups was limited by small sample sizes and should be interpreted cautiously."

HEOR • Journal • Retrospective data • Addiction (Opioid and Alcohol) • Infectious Disease

Magnetically active MnFe2O4@hydrochar composite as a high-performance adsorbent for amoxicillin removal from water. (PubMed, Nanoscale Adv) - "The equilibrium adsorption data were best described by the Langmuir isotherm model with a maximum adsorption capacity (q max) of 4.99 mg g-1 (R = 0.9846). Furthermore, the MnFe2O4@hydrochar nanocomposite was reused for five regeneration cycles and was easily recovered using an external magnet, which demonstrated that it is a stable, reusable, and environmentally sustainable adsorbent for the removal of antibiotics from contaminated wastewater."

Journal

Repurposing of non-steroidal anti-inflammatory drugs as adjunct therapies against biofilm-forming Staphylococcus aureus isolated from camel milk. (PubMed, Trop Anim Health Prod) - "Furthermore, In-Vitro combination therapy trials showed synergistic effect of amoxicillin and trimethoprim+sulphamethoxazole with flunixin meglumine and cefixime with meloxicam. This study will provide baseline data on biofilm-forming S. aureus persistence in the camel population, along with devising an effective therapy against biofilm-forming S. aureus infections."

Journal • Infectious Disease

Comparison of different antibiotics on outcomes in hospitalized patients with COPD exacerbations (ERS 2026) - "The most common antibiotics were ceftriaxone (35.8%), doxycycline (19.5%), azithromycin (15.6%), levofloxacin (8.8%), and amoxicillin (7.4%). While overall outcomes were similar across the most common antibiotic regimens, doxycycline was associated with a significant reduction in 30-day mortality compared to azithromycin in patients treated with orally available antibiotics for AECOPD."

Clinical • Chronic Obstructive Pulmonary Disease • Immunology • Infectious Disease • Pneumonia • Respiratory Diseases

Prevalence and antibiotic resistance pattern of Staphylococcus spp. isolated from acne, and disrupting their antimicrobial resistance: unveiling the potential of Ganoderma lucidum extract. (PubMed, J Genet Eng Biotechnol) - "Gentamicin and rifampin showed 100% susceptibility in both species...Docking and dynamic simulations revealed lucidenic acid D1 strongly and stably binding ermC, while ganoderlactone B and E showed dual binding to mecA and β-lactamase, suggesting inhibition of erythromycin and amoxicillin resistance. ADMET analysis confirmed favorable pharmacokinetics and low toxicity. The study highlights high prevalence of antibiotic-resistant staphylococci in acne and demonstrates the potential of G. lucidum as an effective natural antibacterial and resistance-modifying agent, offering a promising alternative to conventional antibiotics."

Journal • Acne Vulgaris

Antimicrobial resistance in Noma control: a costly neglect within existing neglect. (PubMed, Trop Med Health) - "AMR risks reversing gains in Noma control, and treatment centers may become AMR amplification sites without stewardship. Given limited microbiology data, we recommend adding AMR indicators to WHO and national Noma strategies, integrating anaerobic AMR surveillance at sentinel sites, generating Noma-specific antibiograms, and mandating antimicrobial stewardship in Noma programs. Mainstreaming AMR in Noma research and policy is essential to preserve therapeutic options."

Journal • Review

A Real-World Study on the Efficacy and Safety of Different Doses of Amoxicillin Combined with Potassium-Competitive Acid Blockers in Helicobacter Pylori Eradication (ChiCTR) - P=N/A | N=600 | Not yet recruiting | Sponsor: The First Affiliated Hospital of Nanchang University; The First Affiliated Hospital of Nanchang University

New trial • Real-world evidence • Infectious Disease

A multinational genomic framework for predicting β-lactam resistance in Haemophilus influenzae. (PubMed, J Antimicrob Chemother) - "A recurrence-filtered k-mer-based vocabulary provides a promising standardized genomic framework that complements phenotypic AST, particularly when phenotypic testing is unavailable, incomplete or heterogeneous."

Journal • Infectious Disease • Influenza • Respiratory Diseases

In silico resistance prediction of oral streptococci to recommended prophylactic antibiotics to prevent infective endocarditis upon dental procedures. (PubMed, J Antimicrob Chemother) - "Our in silico study showed that none of the oral Streptococcus assemblies from IE carried resistance genes to the primary regimen recommended for IE prophylaxis following invasive dental procedures. However, several assemblies were potentially resistant to alternative prophylactic regimens for patients allergic to penicillin or ampicillin."

Journal • Cardiovascular

Non-target screening and resistome profiling of hospital wastewater in India: Transformation of contaminants of emerging concern and antimicrobial resistance risks. (PubMed, Water Res) - "Amoxicillin, levofloxacin, and azithromycin (along with antibiotic TPs) exhibited AMR risk (RQAMR>1), with detection of WHO priority and ESKAPE pathogens- Acinetobacter baumannii, Klebsiella sp., Pseudomonas aeruginosa, and Enterobacter sp. With HWW discharged directly into municipal sewers, there could be overburdening of urban treatment networks with CECs and spread of AMR. This study provides one of the most comprehensive datasets on CECs, their TPs, ARBs and ARGs in Indian HWW and underscores the urgent need of upgradation of existing ETPs and integrated AMR surveillance."

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First Report and Integrated Characterization of Aeromonas veronii Associated with the Protected Fish Diptychus maculatus in Xinjiang, China. (PubMed, Animals (Basel)) - "The isolates were susceptible to enrofloxacin, cefotaxime, ceftriaxone, and florfenicol. Intermediate responses were observed for ciprofloxacin, ofloxacin, doxycycline, oxytetracycline, and trimethoprim-sulfamethoxazole, whereas resistance was detected against norfloxacin, neomycin, penicillin, amoxicillin, tetracycline, and erythromycin. In vitro biofilm assays demonstrated weak to moderate biofilm-forming capacity among isolates. These findings provide baseline data for wildlife microbial surveillance and conservation-oriented monitoring of protected fish populations, supporting future investigations into environmental monitoring, genomic characterization, and host-microbe interactions."

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Fourteen-Day Amoxicillin- or Tetracycline-Containing Bismuth Quadruple Therapy versus 14-Day Metronidazole-Based Triple Therapy as the Treatment for Clarithromycin-Resistant Helicobacter pylori Infection: A Multicenter Randomized Controlled Trial. (PubMed, Gut Liver) - "Further large-scale studies are needed to validate these results. Registered retrospectively with the Clinical Research Information Service (CRIS; KCT0012265)."

Clinical • Journal • Infectious Disease