amoxicillin / Generic mfg. - LARVOL DELTA

Integrative Profiling of Antimicrobial Resistance Risks in a Philippine Peri-Urban Community: Insights From Clinical Data, Wastewater Analysis and Community Engagement. (PubMed, Trop Med Int Health) - "The β-lactam antibiotics, particularly cephalosporins from the nearest tertiary hospital and amoxicillin, commonly used for self-medication and livestock treatment, were identified as widely available in the area...Addressing AMR effectively requires a community-centered, multidimensional One Health approach. Priorities include building local capacity, executing targeted public education campaigns, strengthening surveillance systems and enforcing local policy reforms within the local government unit."

Clinical data • Journal

Electrospun sandwich-structured Fe3O4-CeO2/CNTs-Fe3O4-loaded carbon nanofiber mat as a binder-free adsorption-enhanced electro-Fenton cathode for amoxicillin removal. (PubMed, J Environ Manage) - "Mechanistic analysis revealed that the improvement of removal performance originated from synergistic interactions between adsorption of low-level AMX and enhanced degradation of hydroxyl radical (∙OH) electro-generated via as-prepared cathode. This study provides new insights into a binder-free "self-cleaning" electro-Fenton cathode for the removal of antibiotics wastewater."

Journal

Does timing of systemic antibiotics influence periodontal treatment outcomes? A randomized clinical trial. (PubMed, J Periodontol) - "When treating severe gum disease, dentists often combine deep cleaning with antibiotics to help eliminate harmful bacteria. However, the best time to give these antibiotics-at the start or the end of the cleaning process-has never been tested. This study compared two approaches in 68 patients with advanced gum disease: one group received antibiotics during their cleaning sessions over 2 weeks, while the other received them immediately after cleaning finished. Both groups showed similar improvements in gum health after 1 year, with about over half achieving successful treatment outcomes. However, analyzing the bacterial communities revealed an interesting difference: patients who started antibiotics early experienced faster and more thorough changes in their mouth bacteria. Their harmful bacteria disappeared more quickly, and beneficial bacteria formed a stable, protective community sooner. In contrast, the late-antibiotic group showed slower bacterial changes, with..."

Clinical • Journal • Dental Disorders • Infectious Disease • Periodontitis

Exopolysaccharides of Streptococcus mutans Enhance Oral Colonisation and Drug Tolerance in Helicobacter pylori. (PubMed, Int Dent J) - "S. mutans biofilms mediate the adhesion, colonisation, and antibiotic tolerance of oral H. pylori via Gtf-driven EPS biosynthesis."

Journal • Infectious Disease

Continuous Maternal Care of Oral Diseases from Preconception to Lactation. (PubMed, J Dent) - "Perinatal oral disease management safeguards maternal-fetal health by following safety-core principles, adopting evidence-based safe diagnostics/therapies and prioritizing preconception screening & prenatal preventive oral care."

Journal • Review • Dental Disorders • Infectious Disease • Periodontitis

Delayed Cutibacterium acnes Infection of a Thoracic Aortic Graft Presenting as Empyema: A Case Report and Literature Review. (PubMed, J Infect Chemother) - "Seven weeks after the intravenous antibiotic therapy, the patient underwent mediastinal irrigation, explantation of the infected graft, replacement with a rifampicin-soaked prosthesis, and omental flap coverage...Following four additional weeks of intravenous antibiotic therapy, long-term oral amoxicillin suppression was initiated...This case highlights the importance of extended incubation, vigilant diagnostic evaluation, and combined surgical and antimicrobial management in delayed C. acnes vascular graft infections. We also reviewed relevant literature on C. acnes prosthetic vascular infections to contextualize this case."

Journal • Diabetes • Infectious Disease • Metabolic Disorders • Pain • Respiratory Diseases

Randomized controlled trial on the effects of different antibiotic regimens in preterm premature rupture of membranes after 34 weeks. (PubMed, Medicine (Baltimore)) - "The 2 different antibiotic regimens administered to pregnant women diagnosed with PPROM after the 34th week of gestation demonstrated similar clinical effects in terms of maternal and neonatal outcomes. Although the differences in NICU stay duration and the number of chorioamnionitis cases were not statistically significant, we believe that these findings could reach significance in studies with larger sample sizes."

Clinical • Journal • Critical care • Infectious Disease • Obstetrics • CRP

Acute Hemolytic Anemia Due to Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency Triggered by Helicobacter pylori Quadruple Therapy in a Jehovah's Witness: A Case Report. (PubMed, Cureus) - "Although some drugs like antimalarials (primaquine, tafenoquine), sulfonamides, and dapsone are well-known triggers of hemolysis, reports of this adverse effect are rare with standard bismuth-based quadruple therapy for Helicobacter pylori. In this report, we present a 65-year-old male who developed profound anemia (hemoglobin 5.8 g/dL, drop of 4.4 points from baseline) within hours of initiating metronidazole- and tetracycline-containing quadruple therapy...Regarding H. pylori treatment, the patient was initiated on triple therapy (clarithromycin, amoxicillin, proton pump inhibitor), without recurrence of hemolysis...Clinicians should maintain a high suspicion for G6PD deficiency in high-risk populations and exercise caution when prescribing oxidative regimens for H. pylori in these patients."

Journal • Anemia • Hematological Disorders • Infectious Disease • Metabolic Disorders

Efficacy and Safety of Keverprazan-Amoxicillin Dual Regimen in Initial Eradication of Helicobacter pylori Infection: A Multicenter, Randomized Controlled Trial. (PubMed, Helicobacter) - P4 | "Keverprazan 20 mg twice daily with high-dose amoxicillin demonstrates a noninferior efficacy to bismuth quadruple therapy for initial H. pylori eradication."

Journal • Infectious Disease

Probiotic Bacillus Clausii Protects against Amoxicillin-evoked Reproductive Dysfunction through Oxidative Stress Modulation. (PubMed, Probiotics Antimicrob Proteins) - "Testicular tissue samples were analyzed for mechanistic target of rapamycin (mTOR) gene expression and histological changes. However, supplementation with B. clausii mitigates these harmful effects, likely due to its antioxidant properties. The probiotic reduced oxidative stress markers, improved testosterone levels, and alleviated testicular lesions, thereby upregulating the mTOR expression level, which suggests its potential protective role against antibiotic-induced toxicity."

Journal • CAT • mTOR

Acute Exacerbation of Chronic Periapical Pathology in a Dentist: An Autobiographical Case Report. (PubMed, Cureus) - "Self-medication began with paracetamol, escalating to ibuprofen, aceclofenac, and etoricoxib, when pain worsened. Amoxicillin and metronidazole were also taken for infection control...Timely endodontic intervention remains the cornerstone of treatment for acute periapical abscesses. Analgesic prescribing should be individualized and symptom-based rather than fixed-duration, with rotation considered selectively."

Journal • Anesthesia • Infectious Disease • Mood Disorders • Pain

Drug-Drug Interaction Between DW4421 and Amoxicillin/Clarithromycin (clinicaltrials.gov) - P1 | N=36 | Not yet recruiting | Sponsor: Daewon Pharmaceutical Co., Ltd.

New P1 trial

Antibiofilm activity of three-dimensional bacterial nanocellulose scaffolds containing antimicrobial agents. (PubMed, Braz Dent J) - "SEM and CLSM analysis revealed, in the initial periods, a lower number of microorganisms in the experimental groups compared to the control group. BNC scaffolds containing 1% amoxicillin and 1% clindamycin demonstrated greater antimicrobial activity against a multispecies biofilm within the initial periods of incubation."

Journal

Syphilitic Uveitis-Associated Chiasmal Optic Neuritis Presenting As Bitemporal Hemianopia-Like Visual Field Defects. (PubMed, Cureus) - "Oral amoxicillin therapy resulted in complete resolution of the inflammation and recovery of vision. This case highlights that bitemporal hemianopia in patients with syphilitic uveitis may reflect concurrent chiasmal involvement rather than uveitic pathology alone, underscoring the importance of early diagnosis and appropriate treatment are crucial for achieving favorable visual outcomes."

Journal • Genetic Disorders • Infectious Disease • Inflammation • Ocular Inflammation • Ophthalmology • Optic Neuritis • Retinal Disorders • Uveitis

In vitro analysis of biofilm formation and synergistic antibiotic-phage therapy for amoxicillin-resistant Escherichia coli (ESCMID Global 2026) - No abstract available

Preclinical

Prevalence of dual resistance of Helicobacter pylori to clarithromycin and amoxicillin and emergence of novel genetic mutations among clinical isolates from adult patients with gastritis in Tehran, Iran, 2023–2024 (ESCMID Global 2026) - No abstract available

Clinical • Gastrointestinal Disorder • Infectious Disease

A hit with a scar: amoxicillin alters the infant gut microbiome long-term but without fungal expansion (ESCMID Global 2026) - No abstract available

Gastrointestinal Disorder

Unpredictable amoxicillin exposure under high-dose therapy: evidence supporting individualised-guided TDM (ESCMID Global 2026) - No abstract available

Clinical

Amoxicillin dosages in adult patients with streptococcal endocarditis: a PK/PD reappraisal (ESCMID Global 2026) - No abstract available

Clinical • PK/PD data • Cardiovascular

Treatment of early Lyme borreliosis with amoxicillin for ten vs 14 days: a randomised open-label clinical trial (ESCMID Global 2026) - No abstract available

Clinical • Inflammatory Arthritis • Lyme Disease

Lack of synergy between amoxicillin and cefazolin against Enterococcus faecalis: reassessment of a proposed empirical regimen for infective endocarditis (ESCMID Global 2026) - No abstract available

Cardiovascular

Klebsiella pneumoniae hypervirulent clonal complex 66 among amoxicillin-susceptible strains (ESCMID Global 2026) - No abstract available

Infectious Disease • Pneumonia

Triple drug co-delivery within nanosystems for synergistic anti-infective, anti-inflammatory, antinociceptive and neuroregenerative therapeutic effects: a focus on pharmacological and nanotechnological aspects. (PubMed, Eur J Pharmacol) - "Triple drug co-encapsulation has been achieved for non-steroidal anti-inflammatory drugs such as indomethacin, analgesic and antipyretic drugs such as paracetamol, immunosuppressant drugs such as methotrexate, antiretroviral drugs such as efavirenz, lopinavir, ritonavir, and tenofovir, antibacterial drugs such as amoxicillin and clarithromycin, antiulcer drugs such as omeprazole and famotidine, ion channel antagonists such as lomerizine hydrochloride, oxidized adenosine triphosphate, and zonampanel monohydrate, photosensitive molecules such as indocyanine green, genetic material such as MMP-9 siRNA, enzymes such as catalase, and/or plant-derived bioactive compounds such as curcumin, resveratrol, sinomenine, and thymoquinone. These molecules' triple co-encapsulation into nanometric formulations has led to controlled and sustained drug release, extended circulation time, enhanced bioavailability, and reduced systemic toxicity, with an overall improvement in drug..."

Journal • Review • Dermatology • Human Immunodeficiency Virus • Immunology • Infectious Disease • Inflammation • Inflammatory Arthritis • Mood Disorders • Pain • Psoriasis • Psoriatic Arthritis • Rheumatoid Arthritis • Rheumatology • CAT • MMP9

Drug-associated tongue discoloration: a comprehensive assessment of USFDA adverse event reporting system using disproportionality analysis. (PubMed, BDJ Open) - "This comprehensive signal detection revealed several high-priority drug-tongue condition associations using large-scale pharmacovigilance data. Findings carry implications for guiding clinical practice through enhancing adverse effect monitoring for high-risk medications. Priority signals merit validation through further research to optimize benefit-risk assessment and reduce preventable tongue disorders."

Adverse events • Journal

Quantitative risk assessment of antimicrobial resistance exposure among farmers through indirect water reuse for irrigation. (PubMed, J Water Health) - "Lake water used for irrigation was contaminated with sulfamethoxazole/trimethoprim (ST)- and tetracycline (TC)-resistant E. coli, linked to fecal pollution from livestock-related facilities, and amoxicillin (AMX)-resistant E. coli, which was widespread across the lake basin. DALY-based estimates showed that AMR increased the annual disease burden by up to 4.2% compared with a non-AMR scenario, and potentially up to +100% under a high-AMR condition. These findings demonstrate that DALYs effectively quantify AMR-related health burdens associated with irrigation water containing directly or indirectly reused wastewater and support decision-making for AMR risk mitigation."

Journal • Dermatology • Infectious Disease