cefadroxil / Generic mfg. - LARVOL DELTA

Henoch-Schönlein purpura induced by sitagliptin: A case report. (PubMed, SAGE Open Med Case Rep) - "Sitagliptin was discontinued, and the patient was treated with celecoxib, colchicine, and cefadroxil for wound infection. However, urinalysis revealed new 0.3 g/L protein. Overall, this case highlights a new potential association of dipeptidyl peptidase-4 inhibitors with Henoch-Schönlein purpura, which may have systemic consequences."

Journal • Diabetes • Infectious Disease • Metabolic Disorders • Type 2 Diabetes Mellitus • Vasculitis

Primary Genital HSV-2 Infection in a Resource-Limited Setting: Diagnostic Challenges and Clinical Implications. (PubMed, Cureus) - "Treatment with oral acyclovir, cefadroxil, and mefenamic acid, supplemented by topical gentamicin and counselling on recurrence risk and safe sexual practices, led to complete lesion resolution within 14 days and no recurrence at six-week follow-up. These limitations hinder accurate case identification and contribute to the underrecognition of HSV-2 prevalence. Early clinical recognition, prompt antiviral initiation, and strengthened patient education remain essential for mitigating morbidity, preventing recurrence, and reducing transmission in low-resource environments."

Journal • Herpes Simplex • Human Immunodeficiency Virus • Infectious Disease • Pain

Bacillus mycoides bacteremia after dog bite trauma in a patient on chronic suppressive antibiotics. (PubMed, IDCases) - "The patient, who had a chronic Left Ventricular Assist Device (LVAD) in place and was on a chronic suppressive regimen of doxycycline and cefadroxil for a preexisting driveline infection, developed B. mycoides bacteremia despite ongoing antibiotic therapy. She was successfully treated with intravenous ampicillin-sulbactam plus vancomycin, followed by oral ciprofloxacin upon discharge. The patient's recovery was uncomplicated and the final susceptibility testing confirmed pan-susceptibility to all tested agents. This case highlights the potential pathogenicity of B. mycoides in humans and raises questions on the risk factors for infection and optimal management of B. mycoides infections in the setting of relatively limited clinical data."

Journal • Cardiovascular • Infectious Disease • Mood Disorders

Chitosan coated yeast microcapsules for efficient delivery of cefadroxil for the treatment of inflammatory bowel disease. (PubMed, Int J Biol Macromol) - "Cefadroxil-loaded YM coated with chitosan showed significant therapeutic activity in the IBD animal model and also achieved colon targeting. Therefore, this cefadroxil-loaded YM coated with chitosan could be used as a targeted oral drug delivery system for the treatment of IBD."

Journal • Gastroenterology • Gastrointestinal Disorder • Immunology • Inflammation • Inflammatory Bowel Disease

Pro-inflammatory secreted virulence factors of Staphylococcus capitis causing a rare occurrence of severe native hip joint infection. (PubMed, ASM Case Rep) - "The patient was treated with intravenous cefazolin (6 weeks), after which he was transitioned to oral cefadroxil. The organism secreted a neutrophil pro-inflammatory autolysin protease and an analog of the immunodominant antigen B of S. aureus, previously with no known biological function. Our data suggest that the inflammatory lesion in the patient's right hip was due to S. capitis subspecies capitis, and furthermore, it is likely that two secreted proteins (autolysin and an analog of immunodominant antigen B) contributed to the inflammation."

Journal • Immunology • Infectious Disease • Inflammation • Mood Disorders • Orthopedics • Osteoarthritis • Pain • Rheumatology • CRP

Sulopenem etzadroxil/probenecid (Orlynvah) for uncomplicated UTIs. (PubMed, Med Lett Drugs Ther) - No abstract available

Journal • Infectious Disease • Nephrology

Acute Hepatitis During Dalbavancin Infusion: A Rare Adverse Reaction With Implications for Repeat Dosing (ACG 2025) - "He subsequently completed therapy with cefazolin and linezolid and was placed on oral cefadroxil plus doxycycline suppression in view of retained hardware. In pooled data from 2,120 adults across phase 1–3 studies, 17 patients (0.8%) developed post-baseline ALT elevations >3× ULN; within this group, 5 (0.2%) had ALT >10× ULN and one phase 1 subject exhibited ALT >20× ULN—each reversible on follow-up (Table 2)...In this case likely mechanisms include immune-mediated hypersensitivity, similar to vancomycin-induced hepatotoxicity, although rate of cross-reactivity between dalbavancin and vancomycin appears to be very low to negligible...Laboratory Values Pre-infusion and Post-infusion of Dalbavancin Figure: Table 2. ALT Elevation Secondary to Dalbavancin Infusion Regiments"

Fatigue • Hepatology • Immunology • Infectious Disease • Inflammation

Medical Management of an Infusion Site Extravasation Injury After Peripheral Intravenous Infusion of Ado-Trastuzumab Emtansine in a 38-Year-Old Woman with Breast Cancer: A Case Report. (PubMed, Am J Case Rep) - "She was treated with a topical steroid (clobetasol), topical calcineurin inhibitor (tacrolimus), oral antibiotic (cefadroxil), high-dose vitamin D (ergocalciferol), and pain management (gabapentin) with almost complete resolution in 4 weeks. CONCLUSIONS This case report describes a T-DM1 skin extravasation treated with multimodal medical measures as opposed to a more conservative approach. We reaffirm that the use of port access when administering T-DM1 is critical to prevent extravasation, and we recommend multimodal management, including antibiotics and topical therapies, to prevent infection and expedite wound healing if extravasation occurs."

Journal • Breast Cancer • Dermatology • Hormone Receptor Breast Cancer • Infectious Disease • Oncology • Pain • Solid Tumor

Prevalence, Serotypes, and Antimicrobial Resistance of Salmonella Species in Ready-to-Eat Foods in Erbil, Iraq. (PubMed, Microorganisms) - "All isolates were susceptible to colistin, cefadroxil, and gentamicin, while showing high resistance to streptomycin (52%) and levofloxacin (48%). Contamination peaked during the warmer months, particularly in June (15.4%) and May (11.5%), when compared to the other sampling months. These findings highlight significant food safety concerns related to Salmonella contamination and AMR in RTE foods, emphasizing the urgent need for enhanced hygiene practices and regulatory oversight especially among street vendors."

Journal • Infectious Disease

Phenotypic and molecular phylogeny of Klebsiella pneumoniae isolated from respiratory-diseased pet cats in Iraq. (PubMed, J Adv Vet Anim Res) - "The screening for the antibiotic susceptibility reported a higher sensitivity to ceftiofur, ciprofloxacin, cefepime, amikacin, gentamicin, cefotaxime, and meropenem, as well as ceftazidime, ceftriaxone, and doxycycline, imipenem, as well as clotrimazole and tetracycline. In contrast, the more significant resistant K. pneumoniae isolates were detected to clarithromycin, clindamycin, amoxicillin, cefixime, chloramphenicol, erythromycin, cephalexin, cefadroxil, azithromycin, and nalidixic acid, whereas, significant semi-sensitivity was shown to tylosin...This study indicates the high prevalence of K. pneumoniae in respiratory-diseased cats with significant appearance of antibiotic resistance in study isolates. Sequencing data referred to the close related association of study isolates to human K. pneumoniae isolates, suggesting the increased prevalence of nosocomial infections in veterinary medicine."

Journal • Infectious Disease • Pneumonia • Respiratory Diseases

Prescription Trends by Orthopedic Surgery Provider: Review of the Medicare Part D Prescribers - by Provider and Drug, 2013-2021. (PubMed, Orthopedics) - "In line with national guidelines, claims for NSAIDs are increasing and claims for opioid pain medications and AOMs are decreasing. Claims for outpatient antibiotics are increasing, which is of significant concern, given renewed focus on antibiotic stewardship."

Journal • Medicare • Reimbursement • Review • US reimbursement • Orthopedics • Pain

Common skin and soft tissue infections-current recommendations (PubMed, Dermatologie (Heidelb)) - "They are sufficiently treated with, e.g., oral cefadroxil or intravenous cefazolin. The spectrum of causative bacteria is broader and must be considered for calculated antibiotic therapy. This review is intended to provide targeted and successful antibiotic therapy and to reduce adverse effects and development of resistant bacteria."

Journal • Review • Dermatology • Diabetes • Infectious Disease • Metabolic Disorders • Pain • Renal Disease • Thermal Injury

Cefadroxil-Induced Radiation Recall Dermatitis: A Case Report and Review of the Literature. (PubMed, Cureus) - "The antibiotic was stopped, and her affected breast was treated with clobetasol cream 0.05%, and the patient's RRD resolved. We review literature emphasizing cefadroxil antibiotic as a causative agent of RRD."

Journal • Dermatitis • Dermatology • Immunology • Orthopedics

Isolation, Identification, and Drug Sensitivity Test of Pseudomonas aeruginosa from Cynomolgus Monkey (Macaca fascicularis). (PubMed, Vet Sci) - "The results of drug sensitivity tests showed that strain PA/CM-101101 was sensitive to amikacin, azithromycin, cefoperazone, ceftazidime, ceftriaxone, ciprofloxacin, gentamicin, imipenem, levofloxacin, meropenem, norfloxacin, ofloxacin, and polymyxin B; however, it displayed resistance to ampicillin, cefadroxil, cefazolin, erythromycin, and vancomycin. It also provides a reference for molecular epidemiological studies. To our knowledge, this is the first time P. aeruginosa isolated from the diarrhea feces of cynomolgus monkey has been reported."

Journal • Preclinical

In-vitro assessment of probiotic potential of bacteria isolated from chicken gastrointestinal tract. (PubMed, Antonie Van Leeuwenhoek) - "All isolates were sensitive against all the antibiotics, with maximum zone of inhibition against velosef and cefadroxil in the E. durans strain PUPro5. Cholesterol degradation efficiency of isolates ranged between 195.2 and 204.6 mg/dl. Bacteria characterized in the present study exhibit probiotic potential and can be recommended for testing their effect on chickens' growth and meat quality through broiler diet supplementation."

Journal • Preclinical • Gastrointestinal Disorder

Cefadroxil-Mupirocin Integrated Electrospun Nanofiber Films for Burn Wound Therapy. (PubMed, Curr Drug Deliv) - "The study demonstrates that cefadroxil-mupirocin nanofiber films provide superior antibacterial activity and faster wound healing rates, highlighting their potential in advanced burn wound management."

Journal

An unusual case of Mycobacterium marinum cutaneous infection in an immunocompetent patient: a diagnostic challenge (CDA 2025) - "A course of cefadroxil and topical corticosteroids did not improve the condition...Rifampicin was resumed, and doxycycline replaced clarithromycin one week later. Treatment is ongoing Conclusion This case underscores the importance of considering M. marinum in chronic granulomatous skin lesions, even in patients without traditional risk factors. It emphasizes the importance of repeated biopsies for mycobacterial culture to ensure accurate diagnosis and prompt treatment."

Clinical • Dermatology • Infectious Disease • Inflammation • Nontuberculous Mycobacterial Disease

PRIMARY PYOMYOSITIS: EXPERIENCE OF 24 YEARS IN A THIRD LEVEL HOSPITAL OF SOUTHERN EUROPE (ESPID 2025) - "Cefadroxil was the most frequent oral antibiotic (37.5%) at discharge...Complications were rare, involving longer hospital admissions. MRI remains the gold standard, but ultrasound could be useful ."

Clinical • Infectious Disease • Septic Shock

DACAT: Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing (clinicaltrials.gov) - P2 | N=300 | Recruiting | Sponsor: Massachusetts General Hospital | Not yet recruiting ➔ Recruiting

Enrollment open • Allergy • Immunology

Colorimetric and fluorometric dual-mode sensing of cefadroxil based on peroxidase-like activity of iron and nitrogen co-doped carbon dots. (PubMed, Spectrochim Acta A Mol Biomol Spectrosc) - "For the fluorometric method, the response ratio increased with rising CFD's concentrations from 0.01 to 400 µM with LOD of 0.004 µM. The NCDs-Fe was applied to detect CFD in real samples, achieving recovery rates of 96.5 % to 104.0 % with RSD values below 4.12 %."

Journal

Extended oral antibiotics in primary and revision total joint arthroplasty: An update. (PubMed, J Clin Orthop Trauma) - "Several studies have demonstrated substantial reductions in PJI rates, particularly among high-risk populations receiving a 7-day course of antibiotics, mainly with use of cefadroxil...There is a need for high quality randomized controlled trials to help identify optimal patient selection criteria, antibiotic type, and duration to effectively balance the benefits of EOAP against potential risks. Although there is limited evidence of significant antibiotic associated complications with the use of EOAP, care should be utilized prior to widespread adoption with antibiotic stewardship in mind."

Journal • Infectious Disease • Orthopedics

Retrospective Review of the Infection Rate of Lower Extremities Treated With Mohs Micrographic Surgery With and Without Prophylactic Antibiotics. (PubMed, Dermatol Surg) - "There is no decrease in infection rate of below the knee MMS with preoperative prophylactic antibiotics."

Journal • Retrospective data • Dermatology • Infectious Disease • Oncology

Antibiotic Usage for Treatment of Acute Upper Respiratory Tract Infections in Children in Lithuania from 2018 to 2022. (PubMed, Antibiotics (Basel)) - "Of all penicillin-class antibiotics, the most popular choice was amoxycillin. The primary choice of cephalosporin was cefadroxil, and the primary choice of macrolide was clarithromycin...The most common diagnoses during these visits were acute tonsillitis and acute pharyngitis, and most antibiotic prescriptions were for children in the 0-5 age group. If Lithuania's National Recommendations on the Rational Use of Antibiotics were implemented during the analyzed period, the prescribing tendencies would not meet them."

Journal • Infectious Disease • Inflammation • Otorhinolaryngology • Pediatrics • Respiratory Diseases

Identification, synthesis, isolation, and characterization of formulation related degradation impurity of Cefadroxil Oral suspension. (PubMed, J Chromatogr B Analyt Technol Biomed Life Sci) - "The present work is focused on the identification, synthesis, and characterization of the unknown impurity by employing several sophisticated analytical techniques. Such as High-resolution mass spectroscopy (HRMS), One dimensional (1D) and two dimensional (2D) nuclear magnetic resonance spectroscopy."

Journal • Cerebral Hemorrhage • Dermatology • Infectious Disease • Nephrology • Otorhinolaryngology • Pulmonary Disease • Respiratory Diseases

Outpatient Antibiotic Use in Orthopaedic Surgery Practice is Increasing: A Review of Medicare Part D Claims from 2013 to 2021 (AAOS 2025) - "The use of amoxicillin, amoxicillin/clavulanic acid, penicillin V, cephalexin, cefadroxil, mupirocin, clindamycin, sulfamethoxazole / trimethoprim, and doxycycline significantly increased with time while the use of ciprofloxacin, levofloxacin, azithromycin, and vancomycin significantly decreased (Table 2). Outpatient antibiotic prescriptions by orthopaedic surgery providers increased between 2013 and 2021 with greatest increases in the use of cefadroxil, doxycycline, amoxicillin, and clindamycin. Considering national-level guidelines advocating for increased antibiotic stewardship and growing antibiotic resistance, this is of notable concern. Further study is needed to identify if these practice patterns represent rising use of prophylactic versus therapeutic antibiotics in orthopaedic surgery practice."

Clinical • Medicare • Reimbursement • Review • Surgery • US reimbursement • Orthopedics