enoxaparin sodium / Generic mfg. - LARVOL DELTA

Endovenous reconstruction of congenital iliocaval anomalies. (PubMed, J Vasc Surg Cases Innov Tech) - "The two patients who initially presented with DVT were discharged on therapeutic Lovenox and clopidogrel after stenting, whereas one patient who did not present with thrombosis was discharged on clopidogrel. All patients achieved resolution of lower extremity pain, swelling, and venous claudication. Through careful selection and understanding of the anatomy, etiology, and management strategies, patients can be successfully reconstructed with an endovascular approach."

Journal • Cardiovascular • Hematological Disorders • Pain • Thrombosis

Thromboprophylaxis in Patients Undergoing Orthopedic Surgeries; Using Propensity Score Matching (clinicaltrials.gov) - P=N/A | N=0 | Withdrawn | Sponsor: Hanoi Medical University | N=4000 ➔ 0 | Unknown status ➔ Withdrawn

Enrollment change • Trial withdrawal • Cardiovascular • Hematological Disorders • Orthopedics • Thrombosis • Venous Thromboembolism

A Silent Catastrophe: Aortoesophageal Fistula Presenting as Hemorrhagic Shock (ACG 2026) - "Case Description/ A 71 year-old male with a past medical history of esophageal adenocarcinoma with signet cell ring features status-post 10 cycles of palliative radiation and one cycle of chemotherapy with FOLFOX (folinic acid, fluorouracil and oxaliplatin) and immunotherapy with pembrolizumab presented with a chief complaint of vomiting blood. Of note, the patient had recently been diagnosed with a pulmonary embolism and was on therapeutic enoxaparin prior to arrival...However, our patient in this case was not a candidate for definitive repair due to his overall poor prognosis due to his metastatic disease. Figure: Axial View CT Abdomen/Pelvis demonstrating fistula between esophagus and proximal descending thoracic aorta."

Cardiovascular • Esophageal Adenocarcinoma • Esophageal Squamous Cell Carcinoma • Gastrointestinal Disorder • Pulmonary Embolism • Respiratory Diseases • Solid Tumor • Squamous Cell Carcinoma

Cerebral venous sinus thrombosis mimicking brain metastasis in EGFR-mutant lung cancer with small-cell transformation (EANO 2026) - "Following transformation to high-grade neuroendocrine carcinoma (small-cell carcinoma) while receiving osimertinib, she received two lines of systemic chemotherapy: cisplatin-etoposide and lurbinectedin...She underwent whole-brain radiotherapy (WBRT) with a total dose of 27.5 Gy in 10 fractions using intensity-modulated radiotherapy (IMRT) and was started on irinotecan-carboplatin chemotherapy regimen...Anticoagulation with enoxaparin followed by apixaban led to radiological resolution and full neurological recovery... CVST can closely mimic hemorrhagic brain metastasis on standard imaging. In this case, the prothrombotic state likely resulted from multifactorial mechanisms, including malignancy-induced tissue factor upregulation and radiation-induced endothelial activation. Integrating MRV and sequence-based MRI interpretation is essential to prevent unnecessary neurosurgical interventions and ensure timely anticoagulation in cancer patients with acute neurological..."

Endocrine Cancer • Lung Adenocarcinoma • Lung Cancer • Neuroendocrine Carcinoma • Non Small Cell Lung Cancer • Oncology • Solid Tumor • EGFR • TP53

Direct Oral Anticoagulants (DOAC) vs Enoxaparin: A Triple Center Propensity Matched Scoring of Post Discharge VTE Prophylaxis Outcomes (ACS-CLINCON 2026) - "Abstract is embargoed at this time."

Title: Real-World Comparative Outcomes of Apixaban Versus Enoxaparin in Cancer-Associated Thrombosis (ESMO 2026) - No abstract available

Clinical • Real-world • Real-world evidence • Oncology

Perioperative Management of Patients on Factor XI or Factor XIa Inhibitors. (PubMed, J Thromb Haemost) - "Periprocedural data from completed Phase 2 clinical trials demonstrate two observations: 1) for primary venous thromboprophylaxis of patients undergoing major orthopedic surgery who are at risk of major bleeding, strategies to inhibit FXI result in a lower risk of venous thromboembolism and lower clinically relevant bleeding compared to current recommended therapy such as enoxaparin; 2) for patients on long-term FXI inhibitors undergoing elective procedures, there is potential for simpler and potentially safer periprocedural paradigms without interruption of FXI inhibitors compared to the simplified and standardized approach with direct oral anticoagulants, at least for low and (some) moderate bleed risk procedures. Further work, including tailored perioperative prospective management studies, targeted FXI inhibitor reversal strategies, and assays to assess the anticoagulant effects of FXI inhibitors in perioperative settings are needed."

Journal • Review • Cardiovascular • Hematological Disorders • Hemophilia • Orthopedics • Venous Thromboembolism

Repurposing Low-Dose Enoxaparin in Chronic Plaque Psoriasis: A Prospective Study Demonstrating Clinical Improvement and IL-17 Modulation (EADV 2026) - No abstract available

Clinical • Dermatology • Immunology • Plaque Psoriasis • Psoriasis • IL17A

Enoxaparin in Recalcitrant Disseminated Lichen Planus: Complete and Sustained Clinical Response in a Patient with Contraindications to Standard Therapy (EADV 2026) - No abstract available

Clinical • Dermatology • Dermatopathology • Lichen Planus

ENOXAPARIN INDUCED BULLOUS HEMORRHAGIC DERMATOSIS: RARE BUT NOT TO BE FORGOTTEN ENTITY (EADV 2026) - No abstract available

Dermatology • Hematological Disorders

Enoxaparin Injection-Site- Triggered Pemphigoid Gestationis: A RareAtypical Presentation and Proposed Isomorphic Mechanism. (EADV 2026) - No abstract available

Immunology

136 hours of Long Term Normothermic Machine Perfusion of Human Kidneys (TTS 2026) - "Regular additives of tazocin, clexane, fluconazole and methylprednisolone were given... To date, this remains the longest period of normothermic machine perfusion of human kidneys globally. Our institute has developed an innovative model to potentially keep human kidney grafts viable for extended periods, creation a platform for experimentation and optimisation."

Chronic Kidney Disease • Nephrology

Exploratory Analysis of Thromboinflammatory and Hematological Changes Following Electrolytic Femoral Vein Injury in Wistar Rats. (PubMed, Cureus) - "Methods Twenty-four female Wistar rats (approximately 15 months old; age varied slightly in weeks between sequentially allocated groups) were allocated to a sham control group (n = 4), an untreated electrolytic injury control group (n = 4), and an electrolytic injury group treated with either enoxaparin or rivaroxaban (n = 8 each). MPO showed potential as a thromboinflammatory biomarker. However, given the limited detection of thrombus, these findings require validation in larger studies, using a more reliable thrombosis induction protocol."

Journal • Preclinical • Cardiovascular • Hematological Disorders • Inflammation • Thrombosis • MPO

Rivaroxaban vs Enoxaparin After Cesarean Section: Laboratory Thromboprophylaxis Outcomes (clinicaltrials.gov) - P=N/A | N=62 | Recruiting | Sponsor: Wolfson Medical Center

New trial • Cardiovascular • Venous Thromboembolism

Association Between Tolvaptan Exposure and Venous Thromboembolism Risk in ADPKD: A Real-World Propensity-Matched EHR Study. (PubMed, Nephrology (Carlton)) - "In this large propensity-matched real-world cohort, tolvaptan exposure was associated with lower risks of VTE and mortality among patients with ADPKD. Given the retrospective observational design and the possibility of residual confounding, these findings should be interpreted as associative and hypothesis-generating rather than causal. Further prospective studies incorporating imaging-based measures of disease severity are warranted."

Journal • Real-world evidence • Retrospective data • Autosomal Dominant Polycystic Kidney Disease • Cardiovascular • Genetic Disorders • Hematological Disorders • Nephrology • Polycystic Kidney Disease • Renal Disease • Respiratory Diseases • Venous Thromboembolism

Disseminated Melioidosis Complicated by Dural Venous Sinus Thrombosis: A Case Report. (PubMed, Cureus) - "The patient was initially treated with intravenous meropenem, followed by ceftazidime and oral trimethoprim-sulfamethoxazole as part of eradication therapy. Therapeutic anticoagulation with enoxaparin was also initiated. Follow-up imaging demonstrated significant resolution of the visceral abscesses and pulmonary lesions."

Journal • Back Pain • Cardiovascular • Diabetes • Hematological Disorders • Hypertension • Infectious Disease • Metabolic Disorders • Musculoskeletal Pain • Pain • Pneumonia • Pulmonary Disease • Pulmonary Embolism • Respiratory Diseases • Thrombosis

A Novel COMBinATorial Therapy With Albumin and Enoxaparin in Patients With Decompensated Cirrhosis at High-risk of Poor Outcome (COMBAT Trial). (clinicaltrials.gov) - P2 | N=90 | Recruiting | Sponsor: European Foundation for Study of Chronic Liver Failure | Trial completion date: Sep 2025 ➔ Oct 2026 | Trial primary completion date: Sep 2025 ➔ Oct 2026

Trial completion date • Trial primary completion date • Fibrosis • Gastroenterology • Hepatology • Immunology • Liver Cirrhosis • Liver Failure

Change associated with enoxaparin prophylactic anti-Xa levels during prolonged hospitalization in trauma patients. (PubMed, Injury) - "Approximately one-quarter of patients exhibited clinically significant change between the first anti-Xa level within prophylactic target range and repeat anti-Xa levels obtained at least 6 days later in this evaluation. Subsequent larger studies are necessary to validate these hypothesis generating findings."

Journal • Cardiovascular • Hematological Disorders • Thrombosis • Venous Thromboembolism

Randomized Assessor-Masked Trial of Moderate Graduated Compression Stockings for Popliteal Vein Dilation During Long-Haul Economy-Class Air Travel After Aesthetic Surgery (clinicaltrials.gov) - P=N/A | N=160 | Recruiting | Sponsor: Research Inc

New trial • Aesthetic Medicine

Anti-Xa Activity and Global Hemostatic Response After Prophylactic Enoxaparin in Term Pregnancy: A Prospective Matched-Cohort Study. (PubMed, Anesth Analg) - No abstract available

Journal

Undiagnosed von Willebrand Disease Presenting as Delayed Hematoma after Total Hip Arthroplasty: A Case Report. (PubMed, J Orthop Case Rep) - "He received post-operative thromboprophylaxis with enoxaparin 30 mg every 12 h for 4 days...Delayed or atypical hematoma after total hip arthroplasty should prompt evaluation for occult bleeding disorders, including von Willebrand disease. Early recognition and individualized hemostatic planning are essential to reduce morbidity in future procedures, and this report highlights the value of a structured perioperative bleeding assessment in medically complex arthroplasty candidates."

Journal • Cardiovascular • Chronic Kidney Disease • Chronic Obstructive Pulmonary Disease • Diabetes • Genetic Disorders • Hematological Disorders • Hemophilia • Immunology • Metabolic Disorders • Nephrology • Obesity • Orthopedics • Peripheral Arterial Disease • Pulmonary Disease • Renal Disease • Respiratory Diseases

Prevention of Thromboembolism Using Apixaban vs Enoxaparin Following Spinal Cord Injury (clinicaltrials.gov) - P=N/A | N=60 | Recruiting | Sponsor: Loewenstein Hospital | Trial completion date: Feb 2026 ➔ Feb 2028 | Trial primary completion date: Aug 2025 ➔ Aug 2027

Trial completion date • Trial primary completion date • Cardiovascular • CNS Disorders • Musculoskeletal Diseases • Orthopedics

Acute otitis media complicated by mastoiditis and otogenic transverse-sigmoid sinus thrombosis in an adult: a case report on infectious pathogenesis and multidisciplinary therapy. (PubMed, Front Med (Lausanne)) - "We report the case of a 32-year-old man with no relevant medical history who presented with a 3-week history of right-sided otorrhea and otalgia, with clinical worsening despite outpatient amoxicillin-clavulanic acid...The patient was managed using a stepwise multidisciplinary approach that included broad-spectrum intravenous antibiotics, anticoagulation with enoxaparin, myringotomy with ventilation tube placement, mastoidectomy, lateral sinus puncture, and drainage of a mastoid tip abscess...It also highlights the importance of early contrast-enhanced imaging, targeted venous assessment, antimicrobial escalation, surgical source control, individualized anticoagulation, and structured follow-up in adults with complicated otogenic infections. Because microbiological confirmation and postoperative vascular imaging were not available, the infectious and thrombotic interpretation should be considered clinically inferred rather than directly demonstrated."

Journal • Cardiovascular • Dermatology • Hematological Disorders • Infectious Disease • Otorhinolaryngology • Thrombosis

GI-Predominant IgA Vasculitis in a Geriatric Patient (ACG 2026) - "Case Description/ Our patient is an 82-year-old female with atrial fibrillation on rivaroxaban that presented with melena, abdominal pain, and 2 weeks of bilateral lower-extremity purpura...A trial of enoxaparin resulted in hematochezia requiring transfusion...These were also present in the second and fourth parts of the duodenum. The ileitis seen on colonoscopy had a similar appearance."

Clinical • Acute Kidney Injury • Atrial Fibrillation • Cardiovascular • Crohn's disease • Focal Segmental Glomerulosclerosis • Gastroenterology • Gastrointestinal Disorder • Geriatric Disorders • Glomerulonephritis • Immunology • Infectious Disease • Inflammation • Inflammatory Bowel Disease • Lupus Nephritis • Nephrology • Renal Disease • Vasculitis

The anticoagulation dilemma: A case report of pulmonary embolism in a gastric cancer patient with concurrent gastrointestinal bleeding and thrombocytopenia. (PubMed, Medicine (Baltimore)) - "This case underscores the importance of individualized anticoagulation strategies in patients with cancer and PE, particularly those at high risk of bleeding or heparin-induced thrombocytopenia. This highlights the need for further research and clinical guidelines to optimize the management of venous thromboembolism in this vulnerable population. However, owing to the lack of relevant laboratory testing resources at our medical institution, we were unable to confirm this through laboratory verification."

Journal • Cardiovascular • Gastric Cancer • Gastroenterology • Hematological Disorders • Oncology • Pulmonary Embolism • Respiratory Diseases • Solid Tumor • Thrombocytopenia • Venous Thromboembolism