EVT-401 / Evotec, Conba - LARVOL DELTA

Identification and characterization of related substances in EVT-401 by hyphenated LC-MS techniques. (PubMed, J Pharm Anal) - "Fourteen RSs including six process-related substances and eight degradation products were detected and identified in EVT-401 with positive ESI high-resolution TOF-MS analysis of their parent ions and the corresponding product mass spectra elucidation, and some of them were further verified by chemical synthesis and NMR spectroscopy. The specific LC-MS method developed for separation, identification and characterization of RSs is valuable for EVT-401 manufacturing process optimization and quality control."

Journal • Biosimilar • Multiple Sclerosis

Evotec H1 2012: Building innovation on the back of profitable growth (Globenewswire) - Evotec partnered in China with Conba especially for inflammation and endometriosis pain in April 2012 for EVT 401 a P2X7 antagonist

Licensing / partnership • Pain