ONG41008 / OsteoNeuroGen - LARVOL DELTA

A Small Molecule That Promotes Cellular Senescence Prevents Fibrogenesis and Tumorigenesis. (PubMed, Int J Mol Sci) - "ONG41008 exhibited a comparable senogenic potential to that of dasatinib. Taken together, this is the first study to demonstrate that a small molecule can arrest uncontrolled proliferation during fibrogenesis or tumorigenesis via both senogenic and senolytic potential. ONG41008 could be a potential drug for a broad range of fibrotic or tumorigenic diseases."

Journal • Fibrosis • Immunology • Lung Cancer • Oncology • Pancreatic Cancer • Solid Tumor • CASP3 • CASP7 • TP53