methylprednisolone sodium succinate liposomal (LC-200) / LipoCure - LARVOL DELTA

Derivatization increases mosquito larvicidal activity of the sesquiterpene lactone parthenin isolated from the invasive weed Parthenium hysterophorus. (PubMed, Pest Manag Sci) - "Structural modification of parthenin (1) through addition of hydroxyl groups increases its larvicidal effects. These findings advance the use of structural modification approach in the development of lead chemical molecules for potential exploitation in larval source management."

Journal • Infectious Disease • Malaria

Healthcare includes remdesivir in the list of essential drugs against Covid-19 [Google translation] (ElNacional.cat) - "The Official State Gazette (BOE) has published...updated the list of drugs considered essential in the management of the health crisis caused by Covid-19....Specifically, bemiparin sodium (3,500 IU) 0.2 ml pre-filled syringes....dexamethasone 20 mg tablets; dexamethasone 40 mg tablets; methylprednisolone 20 mg injectable; norepinephrine (norepinephrine) 1 mg / ml; norepinephrine (norepinephrine) 2 mg / ml; remdesivir 100 mg powder for solution for infusion; remdesivir 100 mg solution for infusion 20 ml; and siltuximab 100 mg powder for solution for infusion. Instead, ipratropium bromide 0.3 mg / ml nasal use and cyclosporine 1 mg / ml eye drops disappear."

Clinical • Infectious Disease • Novel Coronavirus Disease

[VIRTUAL] CD200 EXPRESSION, THE ADVERSE PROGNOSTIC FACTOR IN ACUTE MYELOID LEUKEMIA AND OTHER HEMATOLOGIC MALIGNANCIES: A SYSTEMATIC REVIEW AND META-ANALYSIS (EHA 2020) - "The eligible criteria for an included study were as follows: i) observational studies with the same management protocol across the study, ii) untreated human participants with any hematologic cancer, iii) having CD200 expression analysis, and iv) hazard ratios (HRs) or Kapan-Meier curves for overall survival (OS) comparing CD200 positive (CD200+) with CD200 negative (CD200-) and high CD200 expression (hCD200) with low CD200 expression (lCD200) being available...The subgroup meta-analysis also found that both CD200+ (lnHR = 0.41, 95% CI 0.21–0.61) and hCD200 (lnHR = 0.72, 95% CI 0.34–1.11) was a negative predictor of the overall survival rate of acute myeloid leukemia. Conclusion CD200 is a negative prognostic factor of hematologic malignancies, especially acute myeloid leukemia."

Biomarker • Retrospective data • Review • Acute Myelogenous Leukemia • Hematological Disorders • Hematological Malignancies • Immune Modulation • Inflammation • Leukemia • Oncology

Stimulant drugs are associated with violent and penetrating trauma. (PubMed, Am J Emerg Med) - "Many drugs are present in trauma patients that are not routinely detected on urine drug of abuse tests. Both stimulant drugs and cigarette smoking are indicators of multidimensional hazardous behaviors, which were associated with more violent and penetrating trauma."

Journal