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May 04, 2021
Oral Nanoparticle-Encapsulated Bryostatin-1 Found Effective for Treating Cognitive Deficits in an Alzheimer’s disease Mouse Model
(Businesswire)
- "Aphios Corporation announced today its research demonstrated that orally-administered nanoparticle-encapsulated Bryostatin-1 activates α-secretase and PKC isoforms in vitro, and facilitates acquisition and retention of spatial learning in vivo in an Alzheimer's disease mouse model....'This data indicates that nanoparticle encapsulated formulations of Bryostatin-1 can be administered orally and is quite effective in treating cognitive deficits associated with AD.'"
Preclinical • Alzheimer's Disease • CNS Disorders
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