AngioCal (40 kDA PEGylated anticalin)
/ Palvella Therapeutics
- LARVOL DELTA
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March 15, 2022
EFFECTS OF THE ANEURYSM TREATMENT METHOD ON COIL PACKING DENSITY AND ITS RELATIONSHIP WITH THE OSTIUM AREA.
(PubMed, J Vasc Interv Radiol)
- "In cerebral aneurysms treated with balloon- or stent-assisted coiling, the CPD value does not differ from that in aneurysms treated with simple coiling."
Journal • Cardiovascular • Immunology • Vascular Neurology
May 16, 2017
"What's the silent @Roche $PIRS project aimed &I/O just as Avastin comes off patent $AMGN attacking? Antiangio now required? Ramp PRS-050 up?"
Biosimilar
February 28, 2011
Nonclinical pharmacokinetics and safety of Angiocal, the first VEGF-A-specific alternative scaffold protein entering clinical development for cancer
(AACR 2011)
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Effects on inflammatory cytokines or complement factors was not reported; Exaggerated pharmacodynamic effects consistent with potent VEGF neutralization were seen
Pharmacokinetic data • Oncology
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