AC1Q3QWB
/ Tianjin Medical University General Hospital
- LARVOL DELTA
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October 23, 2023
Compound AC1Q3QWB upregulates CDKN1A and SOX17 by interrupting the HOTAIR-EZH2 interaction and enhances the efficacy of tazemetostat in endometrial cancer.
(PubMed, Cancer Lett)
- "Our results advocate AQB, a recently discovered small-molecule inhibitor, as a promising agent against EC cells. When combined with TAZ, it offers a novel therapeutic strategy for EC treatment."
Journal • Endometrial Cancer • Gynecologic Cancers • Oncology • Solid Tumor • CDKN1A • HOTAIR • SOX17
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