ACP-044 / Acadia Pharma - LARVOL DELTA

Evaluate the Efficacy and Safety of ACP-044 in Subjects With Pain Associated With Osteoarthritis of the Knee (clinicaltrials.gov) - P2 | N=61 | Terminated | Sponsor: ACADIA Pharmaceuticals Inc. | Trial completion date: Jan 2023 ➔ Sep 2022 | Active, not recruiting ➔ Terminated | Trial primary completion date: Dec 2022 ➔ Aug 2022; Study was terminated for business reasons.

Trial completion date • Trial primary completion date • Trial termination • Immunology • Musculoskeletal Pain • Osteoarthritis • Pain • Rheumatology

Evaluate the Efficacy and Safety of ACP-044 in Subjects With Pain Associated With Osteoarthritis of the Knee (clinicaltrials.gov) - P2 | N=61 | Active, not recruiting | Sponsor: ACADIA Pharmaceuticals Inc. | N=240 ➔ 61

Enrollment change • Immunology • Musculoskeletal Pain • Osteoarthritis • Pain • Rheumatology

Evaluate the Efficacy and Safety of ACP-044 in Subjects With Pain Associated With Osteoarthritis of the Knee (clinicaltrials.gov) - P2 | N=240 | Active, not recruiting | Sponsor: ACADIA Pharmaceuticals Inc. | Recruiting ➔ Active, not recruiting

Enrollment closed • Immunology • Musculoskeletal Pain • Osteoarthritis • Pain • Rheumatology

Evaluate the Efficacy and Safety of ACP-044 for the Treatment of Acute Postoperative Pain Following Bunionectomy (clinicaltrials.gov) - P2 | N=239 | Completed | Sponsor: ACADIA Pharmaceuticals Inc. | Active, not recruiting ➔ Completed

Trial completion • Orthopedics • Pain

Evaluate the Efficacy and Safety of ACP-044 for the Treatment of Acute Postoperative Pain Following Bunionectomy (clinicaltrials.gov) - P2 | N=240 | Active, not recruiting | Sponsor: ACADIA Pharmaceuticals Inc. | Recruiting ➔ Active, not recruiting | Trial completion date: Nov 2021 ➔ Apr 2022 | Trial primary completion date: Oct 2021 ➔ Feb 2022

Enrollment closed • Trial completion date • Trial primary completion date • Orthopedics • Pain

Evaluate the Efficacy and Safety of ACP-044 in Subjects With Pain Associated With Osteoarthritis of the Knee (clinicaltrials.gov) - P2; N=240; Recruiting; Sponsor: ACADIA Pharmaceuticals Inc.

Clinical • New P2 trial • Immunology • Musculoskeletal Pain • Osteoarthritis • Pain • Rheumatology

Acadia Pharmaceuticals Reports First Quarter 2021 Financial Results (Businesswire) - "A Phase 2 study evaluating ACP-044 for the treatment of pain associated with osteoarthritis is expected to commence in the second quarter of 2021."

New P2 trial • CNS Disorders • Osteoarthritis • Pain

Evaluate the Efficacy and Safety of ACP-044 for the Treatment of Acute Postoperative Pain Following Bunionectomy (clinicaltrials.gov) - P2; N=240; Recruiting; Sponsor: ACADIA Pharmaceuticals Inc.

New P2 trial • Orthopedics • Pain

Double-blind, Placebo-control, Study to Evaluate the Safety and Pharmacokinetics of CT-044 HCl, in Healthy Volunteers (clinicaltrials.gov) - P1; N=21; Active, not recruiting; Sponsor: Lotus Clinical Research, LLC; Recruiting ➔ Active, not recruiting; Trial completion date: Jun 2020 ➔ Sep 2020; Trial primary completion date: Apr 2020 ➔ Aug 2020

Clinical • Enrollment closed • Trial completion date • Trial primary completion date • Gene Therapies • Pain

Open-label, Crossover, Food Effect Study to Evaluate CT-044 in Healthy Human Volunteers (clinicaltrials.gov) - P1; N=10; Completed; Sponsor: Lotus Clinical Research, LLC; Active, not recruiting ➔ Completed

Clinical • Trial completion • Gene Therapies • Pain

Open-label, Crossover, Food Effect Study to Evaluate CT-044 in Healthy Human Volunteers (clinicaltrials.gov) - P1; N=10; Active, not recruiting; Sponsor: Lotus Clinical Research, LLC; Recruiting ➔ Active, not recruiting

Clinical • Enrollment closed

Open-label, Crossover, Food Effect Study to Evaluate CT-044 in Healthy Human Volunteers (clinicaltrials.gov) - P1; N=12; Recruiting; Sponsor: Lotus Clinical Research, LLC; Not yet recruiting ➔ Recruiting

Clinical • Enrollment open

Open-label, Crossover, Food Effect Study to Evaluate CT-044 in Healthy Human Volunteers (clinicaltrials.gov) - P1; N=12; Not yet recruiting; Sponsor: Lotus Clinical Research, LLC

Clinical • New P1 trial

Double-blind, Placebo-control, Study to Evaluate the Safety and Pharmacokinetics of CT-044 HCl, in Healthy Volunteers (clinicaltrials.gov) - P1; N=24; Recruiting; Sponsor: Lotus Clinical Research, LLC; Not yet recruiting ➔ Recruiting

Clinical • Enrollment open