alburetin (SL200) / Senelix - LARVOL DELTA

Effects of 3'-Sialyllactose on Symptom Improvement in Patients with Knee Osteoarthritis: A Randomized Pilot Study. (PubMed, Nutrients) - " Sixty patients with knee OA with Kellgren and Lawrence grades (KL-grades) 1-4 and Korean Western Ontario and McMaster Universities Osteoarthritis Index (KWOMAC) scores ≥30 were randomly assigned to the placebo (n = 20), 3'-SL 200 mg (n = 20), and 3'-SL 600 mg (n = 20) groups...No severe adverse effects were observed over 12 weeks. 3'-SL reduced pain in patients with knee OA, improved daily life movements, and was safe, suggesting that 3'-SL might be an effective treatment for knee OA without severe side effects."

Clinical • Journal • Immunology • Osteoarthritis • Pain • Rheumatology

Dietary supplementation of Allium mongolicum modulates rumen-hindgut microbial community structure in Simmental calves. (PubMed, Front Microbiol) - "In hindgut, compared with SL0, supplementation of A. mongolicum (SL200, SL400, or SL800) decreased in the relative abundances of Ruminococcaceae_UCG-014 (p < 0.01), Ruminiclostridium_5 (p < 0.01), Eubacterium_coprostanoligenes_group (p < 0.05), and Alistipes (p < 0.05) in feces; Whereas, the relative abundances of Christensenellaceae_R-7_group (p < 0.05), and Prevotella_1 (p < 0.01) in SL800 were higher in feces, to maintain hindgut stability. This study provided evidence that A. mongolicum affects the gastrointestinal of calves, by influencing microbiota in their rumen and feces."

Journal • Gastrointestinal Disorder