allogeneic BM-MSCs / Mayo Clinic - LARVOL DELTA

Cellkine: Allogeneic BM-MSCs in Patients with Lumbar Facet Arthropathy (clinicaltrials.gov) - P1 | N=10 | Completed | Sponsor: Mayo Clinic | Active, not recruiting ➔ Completed | Trial completion date: Oct 2024 ➔ Mar 2024 | Trial primary completion date: Oct 2024 ➔ Mar 2024

Trial completion • Trial completion date • Trial primary completion date • Back Pain • Lumbar Back Pain • Musculoskeletal Pain • Pain • Rheumatology

CellKine clinical trial: first report from a phase 1 trial of allogeneic bone marrow-derived mesenchymal stem cells in subjects with painful lumbar facet joint arthropathy. (PubMed, Pain Rep) - "This patient also reported improvements in mental and social health, along with a notable improvement in the grade of facet synovitis observed at the one-year follow-up MRI evaluation. This case report suggests the safety and feasibility of administering intra-articular allogeneic BM-MSCs, offering therapeutic benefits for pain management and functional activities."

Journal • P1 data • Back Pain • Lumbar Back Pain • Musculoskeletal Diseases • Musculoskeletal Pain • Pain • Rheumatology

Cellkine: Allogeneic BM-MSCs in Patients With Lumbar Facet Arthropathy (clinicaltrials.gov) - P1 | N=10 | Active, not recruiting | Sponsor: Mayo Clinic | Trial completion date: Apr 2024 ➔ Aug 2024 | Trial primary completion date: Apr 2024 ➔ Aug 2024

Trial completion date • Trial primary completion date • Back Pain • Lumbar Back Pain • Musculoskeletal Pain • Pain • Rheumatology

Cellkine: Allogeneic BM-MSCs in Patients With Lumbar Facet Arthropathy (clinicaltrials.gov) - P1 | N=10 | Active, not recruiting | Sponsor: Mayo Clinic | Recruiting ➔ Active, not recruiting | Trial completion date: Apr 2022 ➔ Apr 2024 | Trial primary completion date: Apr 2022 ➔ Apr 2024

Enrollment closed • Trial completion date • Trial primary completion date • Back Pain • Lumbar Back Pain • Musculoskeletal Pain • Pain • Rheumatology • CRP

Cellkine: Allogeneic BM-MSCs in Patients With Lumbar Facet Arthropathy (clinicaltrials.gov) - P1; N=10; Recruiting; Sponsor: Mayo Clinic; Trial completion date: Jul 2021 ➔ Apr 2022; Trial primary completion date: Jul 2021 ➔ Apr 2022

Clinical • Trial completion date • Trial primary completion date • Back Pain • Lumbar Back Pain • Musculoskeletal Pain • Pain • Rheumatology • CRP • MRI

Cellkine: Allogeneic BM-MSCs in Patients With Lumbar Facet Arthropathy (clinicaltrials.gov) - P1; N=10; Recruiting; Sponsor: Mayo Clinic; Trial completion date: Dec 2020 ➔ Jul 2021; Trial primary completion date: Dec 2020 ➔ Jul 2021

Clinical • Trial completion date • Trial primary completion date • Back Pain • Lumbar Back Pain • Musculoskeletal Pain • Pain • Rheumatology • CRP • MRI

Cellkine: Allogeneic BM-MSCs in Patients With Lumbar Facet Arthropathy (clinicaltrials.gov) - P1; N=10; Recruiting; Sponsor: Mayo Clinic; Active, not recruiting ➔ Recruiting

Clinical • Enrollment open • Back Pain • Lumbar Back Pain • Musculoskeletal Pain • Pain • Rheumatology • CRP