albendazole / Generic mfg. - LARVOL DELTA

Delayed-Onset Loiasis: A Case of Loa loa Infection Diagnosed Six Years Post-exposure. (PubMed, Cureus) - "Initial treatment with albendazole led to inflammatory symptoms, highlighting the risk of post-treatment reactions. This case underscores the importance of recognizing loiasis in patients with remote travel history, the need for careful microfilarial burden assessment, and multidisciplinary management to optimize treatment outcomes."

Journal • Eosinophilia • Infectious Disease

Multi-venous thrombosis associated with a perforated hydatid cyst: A rare case report and comprehensive literature review. (PubMed, IDCases) - "The patient was successfully treated with albendazole for the cyst and anticoagulant therapy for the thrombosis, with no recurrence of symptoms during a three-year follow-up period. While multi-venous thrombosis associated with HCD is rare, documented cases highlight the need for increased awareness among physicians to effectively recognize and manage this complication."

Journal • Cardiovascular • Hematological Disorders • Pain • Thrombosis

A Case Report of Taenia saginata Infection and Literature Review. (PubMed, Infect Drug Resist) - "Treatment options included praziquantel, clonidine, albendazole, and traditional Chinese medicine, showing favorable efficacy. The patient responded well to appropriate medical treatment, including traditional Chinese medicine, with favorable outcomes. Surgical intervention was performed when necessary."

Journal • Infectious Disease • Pain

Individual-Level Analysis of the Efficacy of Albendazole and Albendazole-Ivermectin Fixed-Dose Coformulation (FDC) Against Trichuris trichiura and Hookworms. (PubMed, Acta Trop) - "S. stercoralis co-infection was linked to poorer response in the FDC arm, while no covariates influenced albendazole response.ERRi modeling demonstrated the superior efficacy of FDC over albendazole in T. trichiura treatment, with comparable efficacy for hookworms."

Journal • Infectious Disease

Different scenarios and management of complicated hepatic cystic echinococcosis: a case series. (PubMed, J Surg Case Rep) - "Among the cases, two presented with obstructive jaundice, three had exophytic lesions, one had a large, calcified lesion, one exerted a mass effect on the intrahepatic inferior vena cava (IVC), one showed subcapsular extension, and the sixth case involved a large cyst that regressed with albendazole. In conclusion, although surgery remains the primary treatment for complicated hepatic CE, PAIR is preferred for uncomplicated cases. However, surgical challenges may be greater after PAIR."

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First Report of the Anti-Parasitic Effect of a Cannabis sativa full-spectrum Extract on Echinococcus granulosus sensu stricto. (PubMed, Acta Parasitol) - "We demonstrated the in vitro and in vivo efficacy of a full-spectrum extract of C. sativa inflorescences against E. granulosus s.s."

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Cisternal Neurocysticercosis: A Systematic Review and Meta-Analysis of Therapeutic Efficacy, Safety, and Outcomes. (PubMed, J Neurol Surg Rep) - "Recent studies show potential benefits of albendazole in managing cisternal neurocysticercosis (NCC), which reduces parasitic burden...The observed heterogeneity and the variable impact on cyst resolution and seizures underscore the complexity of managing NCC. Further high-quality, large-scale RCTs are essential to solidify these findings and guide treatment protocols, emphasizing the need for multidisciplinary strategies in addressing this challenging condition."

Journal • Retrospective data • CNS Disorders • Epilepsy

Helminthic invasion of the gallbladder: A rare presentation of ascariasis-induced cholecystitis - A case report. (PubMed, Int J Surg Case Rep) - "Gallbladder ascariasis, though rare, should be included in the differential diagnosis of cholecystitis in endemic areas. Timely imaging and appropriate management-whether conservative or surgical-are essential to prevent complications and ensure recovery."

Journal • Eosinophilia • Gastroenterology • Hepatology • Pain • Pancreatitis

Spontaneous disseminated hydatidosis with uterine involvement in an 8-year-old child: a multidisciplinary approach. (PubMed, BMC Infect Dis) - "This case highlights the importance of recognizing hydatid disease in endemic regions and the role of imaging and surgery in achieving good outcomes. This case also underscores the need for further research to elucidate the mechanisms behind such atypical presentations."

Journal • Gastroenterology • Gynecology • Infectious Disease • Obstetrics • Pain • Pediatrics

Hepato-renal hydatid cyst: a case report of diagnosis and management of an uncommon disease presentation. (PubMed, Int J Surg Case Rep) - "This case highlights the necessity of individualized, multidisciplinary management for extensive hydatid disease. Combining medical therapy with tailored surgical approaches ensures optimal patient outcomes. The patient's recovery was uneventful, with no recurrence observed at the 12-month follow-up."

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Does Albendazole Play a Role in Preventing Lung Hydatidosis Relaps? (ERS 2025) - No abstract available

Pulmonary Disease • Respiratory Diseases

Pediatric hepatic hydatid cysts: recurrence risk factors following laparoscopic surgery-a 16-year cohort analysis. (PubMed, Surg Endosc) - "Key predictors of post-laparoscopy recurrence included extended surgical duration and cyst location. Although perioperative albendazole therapy was more frequent in the non-recurrence group, it did not reach statistical significance in reducing recurrence rates. These findings highlight the importance of tailored surgical approaches and careful postoperative monitoring to improve patient outcomes."

Journal • Pediatrics

Hydatid Cyst Rupture Due to Albendazole Treatment. (PubMed, Rev Soc Bras Med Trop) - No abstract available

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Rosmarinus Officinalis L. essential oil: in Silico molecular docking and in vivo nematocidal activity on intestinal and muscular trichinellosis. (PubMed, BMC Complement Med Ther) - "This study is the first to highlight the in silico molecular docking and in vivo anti-Trichinella activity of ROEO. Its potentiality in inducing multistage activity and mitigating the inflammation in both intestine and muscles was greatly indebted to suppressing targeted proteins and its high antioxidant activity."

Journal • Preclinical • Fibrosis • Inflammation • TYMS

ALBENDAZOLE-INDUCED HEPATITIS: A RARE CASE OF SEVERE DRUG-INDUCED LIVER INJURY (UEGW 2025) - No abstract available

Clinical • Hepatology • Inflammation • Liver Failure

First molecular confirmed patient of Alveolar Echinococcosis in India: Case report from a tertiary care hospital in North India. (PubMed, Indian J Med Microbiol) - "The patient underwent albendazole therapy and right hepatectomy, but her condition deteriorated due to post-hepatectomy liver failure, leading to multiorgan dysfunction and death. This case highlights AE's diagnostic complexity in non-endemic regions and underscores the critical role of molecular diagnostics."

Journal • Hepatology • Liver Failure • Oncology

Hepatic Hydatid Cyst Complicated by Biliary Obstruction: A Case Report. (PubMed, Cureus) - "The patient was treated with albendazole and underwent an ERCP (endoscopic retrograde cholangiopancreatography) for biliary involvement...Early diagnosis through imaging and serology is essential, while treatment often involves a combination of antiparasitic therapy and surgical or percutaneous procedures. Long-term monitoring is required to detect recurrence, which can occur years after treatment."

Journal • Pain

Therapeutic impact of Citrus paradisi peel extract on muscular trichinellosis: an in vivo study. (PubMed, J Helminthol) - "Moreover, the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) showed the highest expression reduction in the combination therapy group. These findings highlight the potential of C. paradisi as a complementary therapy to albendazole for treating trichinellosis through muscle larva reduction and mitigation of inflammation."

Journal • Preclinical • Infectious Disease • Inflammation

Assessing the Safety and Efficacy of a Combination Therapy for STH in PSAC in Bangladesh (clinicaltrials.gov) - P2 | N=110 | Not yet recruiting | Sponsor: International Centre for Diarrhoeal Disease Research, Bangladesh

New P2 trial • Infectious Disease

Rupture of Echinococcus granulosus leading to severe hypoxia: preoperative and postoperative management. (PubMed, BMJ Case Rep) - "Epinephrine and oxygen supplementation were administered in the local Paediatric Emergency Service. Albendazole was administered 5 days prior to the surgical intervention.Surgical intervention consisted of endocystectomy and capitonnage, conserving the parenchyma. Spillage during the rupture, which caused bronchial obstruction from degrading scolexes of the contralateral side, was managed through flexible bronchoscopy.The patient experienced a favourable outcome with full clinical and radiological resolution after a 6-month course with albendazole and supportive therapy."

Journal • Acute Respiratory Distress Syndrome • Pediatrics

Pseudocapillaria tomentosa (Nematoda: Capillariidae) in fish and its significance in comprehending host-parasite relationships: A review. (PubMed, Curr Res Parasitol Vector Borne Dis) - "Pseudocapillaria tomentosa can be effectively managed through anthelmintic treatments such as emamectin, fenbendazole, albendazole, and mebendazole as well as preventive measures including maintaining optimal water quality, reducing fish density, and implementing strict quarantine protocols. The gut microbiota plays a crucial role in susceptibility to parasitic infections in zebrafish and an imbalanced or dysbiotic gut microbiome can predispose fish to parasitic infections, while a healthy, balanced microbiome can enhance resistance. Furthermore, probiotic-based interventions are being explored as a way to boost mucosal immunity and modify the gut microbiome to prevent parasitic infections."

Journal • Review • Eosinophilia • Hematological Disorders • Infectious Disease • IFNG • TNFA

Neurocysticercosis in a Non-Endemic Region: A Retrospective Cohort Study at Sheikh Khalifa Medical City (SKMC), Abu Dhabi, UAE. (PubMed, Cureus) - "Diagnosis should follow standardized criteria such as Del Brutto's, and albendazole remains first-line therapy unless lesions are calcified. While NCC is not directly contagious, its transmission through ingestion of Taenia solium eggs underscores the importance of hand hygiene practices and preventive health education. This study highlights the need for greater clinical awareness and further research to support public health planning in non-endemic settings."

Journal • Retrospective data • CNS Disorders • Epilepsy • Pain • Psychiatry

Clinical image: multiple pulmonary, hepatic and Abdominal Wall hydatid cysts. (PubMed, Oxf Med Case Reports) - No abstract available

Journal

Eosinophilic myocarditis due to parasitic infection: A case-based minireview. (PubMed, World J Cardiol) - "The patient presented with severe chest pain and recovered fully after treatment with corticosteroids and albendazole. Drawing insights from this case and existing literature, we discuss the pathophysiology, diagnostic approaches, and therapeutic strategies for parasite-induced EM. Early diagnosis and tailored treatment are essential to improve clinical outcomes, especially in endemic parasitic areas."

Journal • Review • Allergy • Cardiovascular • Immunology • Infectious Disease • Inflammation • Pain

Preparation and Evaluation of an Oral Administration System of Albendazole-Metal-Organic Framework Based on Dual Response to pH and Enzymes. (PubMed, Pharmaceuticals (Basel)) - "Pharmacokinetic analysis revealed that the bioavailability of ABZ@UiO-66-NH2 and ABZ@MIL-125-NH2 was 10.3-fold and 1.8-fold higher, respectively, compared to ABZ. The ABZ@MOFs systems effectively improved ABZ dissolution and oral bioavailability, with ABZ@UiO-66-NH2 showing a dual response mechanism to pH and enzymes."

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