abaloparatide transdermal patch (BA-058-TD) / Radius - LARVOL DELTA

Efficacy and safety of transdermal abaloparatide in postmenopausal women with osteoporosis: a randomized study. (PubMed, J Bone Miner Res) - P3 | "Few new clinical fractures occurred in either group. Noninferiority of abaloparatide-sMTS to abaloparatide-SC for percentage change in spine BMD at 12 months was not demonstrated; however, clinically meaningful increases from baseline in lumbar spine and total hip BMD were observed in both treatment groups."

Journal • Dermatology • Musculoskeletal Diseases • Orthopedics • Osteoporosis • Rheumatology

"$RDUS Radius Health Update on Abaloparatide Transdermal System https://t.co/3Sert3ZsL5" (@stock_titan)

Efficacy & Safety of Abaloparatide-Solid Microstructured Transdermal System in Postmenopausal Women With Osteoporosis (clinicaltrials.gov) - P3; N=474; Completed; Sponsor: Radius Health, Inc.; Active, not recruiting ➔ Completed

Clinical • Head-to-Head • Trial completion • Osteoporosis • Rheumatology

Study to Evaluate and Compare the PK Profiles of Abaloparatide-SC and Abaloparatide-sMTS in a Cohort of Healthy Men and Healthy Women. (clinicaltrials.gov) - P1; N=52; Completed; Sponsor: Radius Health, Inc.; Active, not recruiting ➔ Completed; Trial completion date: Jun 2021 ➔ Nov 2021

Clinical • Trial completion • Trial completion date

Study to Evaluate and Compare the Bioequivalence of Two Abaloparatide-sMTS Treatments in Healthy Women. (clinicaltrials.gov) - P1; N=36; Completed; Sponsor: Radius Health, Inc.; Trial completion date: Feb 2021 ➔ Aug 2021

Clinical • Trial completion date • Osteoporosis • Rheumatology

Study to Evaluate and Compare the Bioequivalence of Two Abaloparatide-sMTS Treatments in Healthy Women. (clinicaltrials.gov) - P1; N=36; Completed; Sponsor: Radius Health, Inc.

Clinical • New P1 trial • Osteoporosis • Rheumatology

Study to Evaluate and Compare the PK Profiles of Abaloparatide-SC and Abaloparatide-sMTS in a Cohort of Healthy Men and Healthy Women. (clinicaltrials.gov) - P1; N=52; Active, not recruiting; Sponsor: Radius Health, Inc.; Recruiting ➔ Active, not recruiting

Enrollment closed

Phase 1b Evaluation of Abaloparatide Solid Microstructured Transdermal System (Abaloparatide-sMTS) in Postmenopausal Women with Low Bone Mineral Density. (PubMed, Clin Drug Investig) - P1 | "Subjects successfully self-administered abaloparatide-sMTS, which provided a consistent pharmacokinetic profile over 29 days and produced s-PINP increases from baseline similar to that observed in the pivotal trial with abaloparatide-SC. Observed patient experience along with the clinical data support continued clinical development of abaloparatide-sMTS."

Clinical • Journal • Dermatology • Musculoskeletal Diseases • Orthopedics • Osteoporosis • Pain • Rheumatology

Efficacy & Safety of Abaloparatide-Solid Microstructured Transdermal System in Postmenopausal Women With Osteoporosis (clinicaltrials.gov) - P3; N=474; Active, not recruiting; Sponsor: Radius Health, Inc.; Recruiting ➔ Active, not recruiting

Clinical • Enrollment closed • Head-to-Head • Osteoporosis • Rheumatology

BA058 Transdermal Phase 3 Study in Women with Osteoporosis (clinicaltrialsregister.eu) - P3; N=474; Ongoing; Sponsor: Radius Health Inc.

Clinical • Head-to-Head • New P3 trial • Metabolic Disorders • Musculoskeletal Diseases • Orthopedics • Osteoporosis