AU2-94 / Aucentra - LARVOL DELTA

AU2-94: A CDK4-specific inhibitor with the marked anti-tumor efficacy (AACR 2024) - "This selectivity can be a reason for the better safety of AU2-94 compared to the clinical CDK4/6 inhibitors. The high oral bioavailability, robust antitumor efficacy and excellent safety profiles make AU2-94 a highly attractive candidate for clinical development."

Clinical • IO biomarker • Brain Cancer • Breast Cancer • CNS Tumor • Colorectal Cancer • Gastrointestinal Cancer • Glioblastoma • HER2 Breast Cancer • Hormone Receptor Breast Cancer • Oncology • Solid Tumor • Triple Negative Breast Cancer • BCL2 • CCNA2 • CCNB1 • CCNE2 • CDK2 • CDKN2A • CDKN2B • FOXM1 • KRAS