AA001 / Shenzhen Zhiyuan Biomedical - LARVOL DELTA

Leuconostoc mesenteroides AA001: A High-Efficiency Nitrite Degrader Facilitating Controlled and Safe Traditional Vegetable Fermentation. (PubMed, Microorganisms) - "Microbial community profiling throughout fermentation revealed that early dominance by this strain rapidly established a lactic acid-driven anaerobic environment, effectively suppressing nitrite-accumulating microorganisms and steering the process toward a stable, safe, and flavor-consistent trajectory. Thus, L. mesenteroides AA001 is a safe starter strain that combines potent nitrite-degrading capacity with fermentation-guiding functionality, effectively ensuring safety and process controllability in traditional vegetable fermentation."

Journal

A Phase Ib, Randomized, Double-blind, Placebo-controlled, Dose-escalation Clinical Trial Evaluating the Safety, Tolerability, and Preliminary Efficacy of AA001 Monoclonal Antibody in Chinese Patients with Mild Alzheimer's Disease and Alzheimer's Disease-Related Mild Cognitive Impairment. (ChiCTR) - P1 | N=36 | Not yet recruiting | Sponsor: Xuanwu Hospital, Capital Medical University; Xuanwu Hospital, Capital Medical University

New P1 trial • Alzheimer's Disease • CNS Disorders • Cognitive Disorders