ATx08-001 / Astellas, Alanza - LARVOL DELTA

Evolution of tet(A) Variant Mediating Tigecycline Resistance in KPC-2-Producing Klebsiella pneumoniae during Tigecycline Treatment. (PubMed, J Glob Antimicrob Resist) - "This is a report on K. pneumoniae carrying both tet(A) mutation and bla, which led to increased tigecycline resistance in K. pneumoniae during tigecycline treatment. This is the first report describing tigecycline resistance of K. pneumoniae first increasing and subsequently decreasing in vivo."

Journal • Infectious Disease • Pneumonia