AUP-55
/ Aurealis Therap
- LARVOL DELTA
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April 27, 2023
Effect of multi-targeting bacterial gene therapy on tumour regression and survival in mouse models of ovarian and intraperitoneal cancer.
(ASCO 2023)
- "When compared to the available data from the CRO, the survival advantage was superior to, for example anti-PD1 and cisplatin treatments in the same model. Cytokine armed Lactococcus cremoris AUP-55 enables multimodal action. Treatment with AUP-55 suggests anti-tumor activity as a single therapeutic entity for the treatment of ovarian cancer and peritoneal carcinomatosis."
Gene therapy • Preclinical • Gene Therapies • Melanoma • Oncology • Ovarian Cancer • Peritoneal Cancer • CSF2 • IL12A • IL18
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