amlodipine/valsartan/hydrochlorothiazide / Generic mfg. - LARVOL DELTA

OPTION TREAT: Candesartan Cilexetil + Chlorthalidone + Amlodipine Versus Exforge HCT®️ for Systemic Arterial Hypertension (clinicaltrials.gov) - P3 | N=702 | Completed | Sponsor: Hospital Israelita Albert Einstein | Recruiting ➔ Completed | Trial completion date: Jul 2024 ➔ May 2025 | Trial primary completion date: Dec 2023 ➔ Mar 2025

Trial completion • Trial completion date • Trial primary completion date • Cardiovascular • Hypertension • Pulmonary Arterial Hypertension

DINAMICS OF ARTERIAL STIFFNESS USING CAVI INDEX DEPENDS ON ADDED STATIN TO FIXED COMBINATION ANTIHYPERTENSIVE THERAPY IN PATIENTS WITH ARTERIAL HYPERTENSION. (PubMed, J Hypertens) - "The added of statin to fixed combination antihypertensive therapy prevented the progression of arterial stiffness in patients with arterial hypertension."

Journal • Cardiovascular • Diabetes • Hypertension • Metabolic Disorders • Pulmonary Arterial Hypertension

[VIRTUAL] Single pill regimen improves persistence and leads lo better clinical outcome compared to identical multi pill combination. Results of START, a German claims data analysis (ESC 2020) - "Each group included 10,801 patients with valsartan/amlodipine, 1,026 with candesartan/amlodipine, 1,823 with amlodipine/valsartan/hydrochlorothiazide (HCT), and 15,349 with ramipril/amlodipine as SP or identical LC. Conclusion A SP regimen improves persistence to medication, reduces cardiovascular events and total mortality compared to identical LC. The results of the START study strongly support the use of a SP concept in the AH medication treatment as recommended by the current ESH/ESC-Guidelines for the treatment of AH."

Clinical • Clinical data • Cardiovascular • Congestive Heart Failure • Coronary Artery Disease • Heart Failure • Hypertension • Myocardial Infarction

Efficacy and safety of amlodipine/valsartan/hydrochlorothiazide single pill combination in Egyptian patients with hypertension uncontrolled on any dual therapy: an observational study. (PubMed, Curr Med Res Opin) - "Aml/Val/HCT SPC significantly reduced BP and was well tolerated in Egyptian patients with hypertension not controlled on any previous dual therapy."

Clinical • Journal • Observational data