Adrenalin (epinephrine) / Endo - LARVOL DELTA

Endo Launches ADRENALIN Ready-to-Use Premixed Bag, the First and Only FDA-Approved, Manufacturer-Prepared Epinephrine Premixed IV Bag (PRNewswire) - "Endo, Inc...announced today the launch of its ADRENALIN (epinephrine in 0.9% sodium chloride injection) ready-to-use premixed bag, the first and only FDA-approved, manufacturer-prepared epinephrine premixed intravenous (IV) bag."

Launch • Allergy • Immunology

Secondary diabetes mellitus in pheochromocytomas and paragangliomas. (PubMed, Endocrine) - "PPGLs represent hypermetabolic states, in which adrenaline and noradrenaline induce insulin resistance in target tissues characterized by aerobic glycolysis, excessive lipolysis, altered adipokine expression, subclinical inflammation, as well as enhanced gluconeogenesis and glucogenolysis. DM management in PPGLs is scarcely studied. The efficacy and safety of newer anti-diabetic medications, such as glucagon-like peptide 1 receptor agonists and sodium glucose cotransporter 2 inhibitors (SGLT2is), as well as potential disease-modifying roles of metformin and SGLT2is warrant further investigation in future studies."

Journal • Review • CNS Tumor • Diabetes • Endocrine Cancer • Metabolic Disorders • Oncology • Solid Tumor