ASP2246
/ Astellas
- LARVOL DELTA
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January 31, 2026
A Novel Therapeutic Approach to Improve Motor Dysfunction in a Non-Human Primate Chronic Ischemic Stroke Model Using mRNA-Lipid Nanoparticles Treatment
(ISC 2026)
- "ASP2246, a novel mRNA-LNP drug, was able to convert astrocytes into neurons in a cell culture model and improved motor dysfunction in a chronic ischemic stroke cynomolgus monkey model. There were no ASP2246-related adverse findings."
Lipid Nanoparticle • Astrocytoma • Brain Cancer • Cardiovascular • Ischemic stroke • Solid Tumor • EDN1 • NEUROD1
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